1,721,057 research outputs found
Allergic Contact Dermatitis to Nickel: From Clinical Aspects to Therapeutic Measures
Full text linkNickel is the major cause of allergic contact dermatitis. It is a widely spread metal, being therefore very difficult to avoid. Nickel cutaneous allergy can occur in occupa-tional and non-occupational contexts and can result from direct cutaneous contact, systemic as well as airborne exposure. Such allergy can manifest with typical lesions of allergic con-tact dermatitis or with peculiar features such as follicular erythemato-micropapular-vescicular lesions. Diagnosis of allergic contact dermatitis to nickel is based on patch test-ing, employing nickel sulfate 5% in petroleum jelly. Reactions to patch test have to be assessed at 48-72 hours, and up to 6 days. Nickel contact dermatitis can be managed with the traditional therapeutic approach used in allergic contact dermatitis. As of today, hyposensitization therapy with oral nickel represents to be the only treatment acting on the pathogenetic mechanisms of nickel allergy
Topical dermocosmetics and acne vulgaris
No full textAcne is a highly common skin disease especially among teenagers. Modern acne treatments are based also on the use of moisturizers, cleansers and sunscreens. In choosing the right cleanser, it is important to consider some aspects: the interaction between skin type and the cleanser, the optimal time and method of cleaning and the cosmetic perception of the patient. The aim of our review is to highlight the importance of choosing the most suitable topical dermocosmetics for the different skin types, as well as the most effective timing and method to combine dermocosmetics with the standard acne treatment. A search in literature for selected key words was performed using PubMed. Additional papers were identified based on author expertise. Treatment of acne patients should include education for proper daily skin hygiene, including protection from environmental damage. However, given the low number of clinical studies on cleansers, it is difficult to make reliable recommendations. The correct choice and use of topical dermocosmetics are fundamental in the management of acne patients. Daily use of moisturizers, cleansers and sunscreens can reduce both inflammatory and non-inflammatory acne lesion counts and may be helpful for acne treatment if combined with specific drugs
Allergic contact dermatitis caused by panthenyl ethyl ether in a patient with psoriasis
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Cold-induced anaphylaxis: the case of a 9-year-old child and review of the literature
No full textBackground and Objective: The present review investigated cold-induced anaphylaxis, a potentially life-threatening condition that occurs after exposure to cold stimuli and is characterized by respiratory distress and/or hypotension. Anaphylaxis is rarely associated to cold-induced urticarial (CU), a particular form of physical urticaria that is difficult to diagnose and manage. The incidence of cold-induced urticaria has been estimated at about 0.05%, higher in colder regions and in women; its pathological mechanisms are still unknown. Methods: The literature was searched via the Medline/PubMed database (http://www.ncbi.nlm.gov/ pubmed). Results and Conclusion: Patients affected by CU should be well-informed about the risk of anaphylaxis and preventive measures. The prevention of CU is based on the avoidance of cold exposure. The most effective treatment is antihistamines symptomatic therapy. Anyway, patients should also carry with them an emergency kit containing corticosteroids, antihistamines and an epinephrine injector. Future studies are necessary to determine the CU pathophysiology so to establish a more targeted management of this important and potentially life-threatening condition
Angioedema-like airborne contact dermatitis caused by Dittrichia viscosa (L.) Greuter in a hunter
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Contact urticaria caused by silk bed quilt in a young atopic female
No full textImmediate allergic reactions to silk, including both anaphylaxis and respiratory disease, are well known 1. Rarely, silk can also induce contact urticaria (CU), which is probably caused by sericin, a water‐soluble glycoprotein, or other antigens from insects of the genus Anthrenus contained in silk material
Allergic contact dermatitis caused by resorcinol and sodium dehydroacetate in a patient with leg ulcers
No full textResorcinol, also known as resorcin (1,3-dihydroxybenzene;
CAS no. 108-46-3), is an important ingredient
of Castellani’s paint solution, an antifungal preparation
that is commonly used in daily dermatological clinical
practice. Apart from its use in hair dyes, resorcinol is
also used in several other topical preparations, because
of its antipruritic, keratolytic and antimycotic properties.
Sodium dehydroacetate (CAS no. 4418-26-2) is a preservative
used in several topical products, in particular for
the treatment of ulcers, and has already been reported
to be sensitizing. We describe a case of allergic
contact dermatitis caused by resorcinol and sodium
dehydroacetate in a patient affected by leg ulcers
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