1,720,971 research outputs found
Superoxide dismutase, catalase and cell dimorphism in Candida albicans cells exposed to methanol and different temperatures.
No full textThe combined effects of methanol and different temperatures on Candida albicans were studied. Growth curve, cell morphology, superoxide dismutase (SOD) and catalase activity levels have been determined. Cell growth in each medium was comparable to 28 degrees C and 37 degrees C. The growth rate was not affected by methanol, in the presence of glucose, while it was much lower in the absence of sugar. Cell dimorphism appeared after thermic stress and it was also dependent on the medium composition. In all media, both SOD and catalase levels were much higher at 37 degrees C. The presence of methanol per se did not affect the enzymatic levels, while the absence of glucose gave higher SOD levels
Periodontitis and platelet count: A new potential link with cardiovascular and other systemic inflammatory diseases
No full textAim: As an infection-driven inflammatory disease, periodontitis could lead to a reactive increase in platelet count. This mechanism could partially mediate the well-documented association between periodontitis and atherosclerotic cardiovascular disease. The aim of this cross-sectional study was to test the presence of an association between periodontitis and platelet count in a representative sample of the South Korea population. Materials and methods: A total of 5,197 subjects representative of 34.9 million of adults were examined. Multivariate regression analyses were applied controlling for age, gender, smoking status, educational level, body mass index, alcoholism, diabetes and hypertension status, vitamin D serum levels and total cholesterol, triglycerides, HDL and LDL blood levels. Results: Compared to the non-severe periodontitis group, subjects with severe periodontitis (CPI = 4) displayed 13,048.93 more platelets for μl of blood (95% CI: 3,296.26–22,801.61, p = 0.009) in the fully-adjusted model. The association between severe periodontitis and platelet count has shown to be highlighted in subjects aged more than 60 years, females, non-smokers and with normal HDL blood levels. A systemic inflammatory biomarker (white blood cell count) explained the 19.25% of this association. Conclusions: Within the limitations of this study, periodontitis—especially severe—is independently associated with a considerable increase in platelet count which is explained, at least in part, by an increase in the systemic inflammation
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Are periodontitis and dental caries associated? A systematic review with meta-analyses
Full text linkAim: The epidemiological relationship between periodontitis and caries remains controversial, and evidence synthesis is currently lacking. Therefore, this systematic review was designed to answer the following PECO question: ‘In human adults (P), do subjects suffering from periodontitis (E) have higher presence/number of untreated carious lesions and caries experience (O) than subjects not suffering from periodontitis (C)?’. Materials and Methods: Observational studies that met specific inclusion criteria established to answer to the PECO question were included. Two review authors independently searched for eligible studies, screened the titles and abstracts, carried out the full text analysis, extracted the data and performed the risk of bias assessment. In case of disagreement, a third review author took the final decision during ad hoc consensus meetings. Data synthesis was carried out through random-effects meta-analyses. Results: A total of 18 studies on 21 cohorts, involving 135,018 participants, were included. Meta-analyses showed a significant association between periodontitis and the presence of at least one tooth with either untreated carious lesions (odds ratio [OR] = 1.63; 95% confidence interval [CI]: 1.32–2.01; p <.00; I2 = 83.0%) or caries experience (decayed and filled teeth ≥ 1) (OR = 1.27; 95% CI: 1.01–1.59; p =.038; I2 = 90.0%). Moreover, subjects with periodontitis exhibited a higher number of surfaces (difference in means [MD] = 0.86; 95% CI: 0.46–1.27; p <.001; I2 = 0.0%) and teeth (MD = 0.35; 95% CI: 0.28–0.42; p <.001; I2 = 69.6%) with untreated carious lesions, as well as a higher number of teeth with caries experience (standardized difference in means [SMD] = 1.46; 95% CI: 0.15–2.78; p =.029; I2 = 98.9%) compared with those without periodontitis. Sensitivity analyses focusing on severe periodontitis as exposure mostly showed consistent results. Estimates for caries experience were only slightly attenuated in adjusted models compared with crude models. Subgroup analyses by caries location also indicated that periodontitis was associated only with root caries, while it was not with caries affecting the anatomical crown. Conclusions: Periodontitis was found to be associated with the presence and number of treated/untreated root carious lesions. Therefore, caries-specific preventive measures (e.g., fluorides) should be considered for individuals with periodontitis
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
SOD and catalase induction on Saccharomyces cerevisiae strains by heavy metals and methanol
No full textAppropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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