93,880 research outputs found
Leveraging Psychology of Virtual Body for Health and Wellness
No full textInformation and communication technologies are becoming more present in people’s daily lives. But what is the final purpose of the mass proliferation of digital devices? Are they helpful in fostering personal growth and individual integration in the sociocultural environment, by promoting satisfaction, opportunities for action and self-expression?
Recently Riva and colleagues underlined that one of the fundamental objectives for our field - cyberpsychology—in the coming decade will be to create technologies that contribute to enhancement of happiness and psychological well-being (Botella et al., 2012; Riva, Banos, Botella, Wiederhold, & Gaggioli, 2012; Wiederhold & Riva, 2012). In particular, these authors suggested that it is possible to use technology to manipulate the quality of personal experience, with the goal of increasing wellness, and generating strengths and resilience in individuals, organizations, and society
Guglielmo Riva (1627-1677) and the end of Hepatocentrism : a 17th-Century Painting
No full textDuring the seventeenth century, the description of the lymphatic system provided a decisive contribution to resolving the misconceptions of Galenic physiology concerning the production of blood in the liver. The transition from a liver-centered (hepatocentrism) to a heart-centered model (cardiocentrism) was fundamental in the history of medicine, since it allowed the role of the liver and of the heart in the bodily processes to be more correctly identified. The modification of the medical knowledge on the liver and its functions during that period is well represented in a 17th-century painting,"ll Fegato" ("The Liver"), probably belonging to the "anatomical museum" of the Roman surgeon Giovanni Guglielmo Riva (1627-1677). In particular, this Italian physician significantly contributed to the discovery of the lymphatic system and to the study of the hematopoiesis. Thus, this painting as well as the figure of Guglielmo Riva would deserve a major consideration in the history of medicine and of hepatology in particular
Advisory Editor profile: Carla Riva-Rossi
No full textDr. Carla Riva-Rossi has over 25 years’ experience studying the evolutionary ecology of anadromous fishes. She received an MS in biological sciences from the Facultad de Ciencias Naturales, Universidad Nacional de la Patagonia in Argentina and a PhD in biology from the Universidad Nacional del Comahue. She carried out postdoctoral research in salmonid population genetics at the Centro Nacional Patagónico, CONICET, and she is now an Adjunct Researcher at the Instituto de Diversidad y Ecología Austral (IDEAus-CONICET). There, she leads the research group of Ecology, Evolution, and Habitat of Migratory Fish in Patagonia, mentoring postgraduate students and young researchers in fish taxonomy, systematics, population genetics, and ecology. She also holds the position of Vice Director of IDEAus...Fil: Docker, Margaret F.. University of Manitoba; CanadáFil: Riva Rossi, Carla Marcela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto de Diversidad y Evolución Austral; Argentin
Epistolario: Fabián - Guzmán Vol. 2
No full text1389 p. ; 22 cm.El volumen 1, del tomo XVI de Obras Completas de José de la Riva-Agüero y Osma, nos presenta el epistolario de Riva-Agüero correspondiente a las cartas de los corresponsales cuyos apellidos comienzan con las letras «F», entre los apellidos Fabián - Funeg
Epistolario: Fabián - Guzmán Vol. 1
No full text828 p. ; 22 cm.El volumen 1, del tomo XVI de Obras Completas de José de la Riva-Agüero y Osma, nos presenta el epistolario de Riva-Agüero correspondiente a las cartas de los corresponsales cuyos apellidos comienzan con las letras «F», entre los apellidos Fabián - Funeg
54esima Biennale di Venezia - Padiglione della Repubblica di San Marino
No full textTitolo del progetto: "Luce In-azione"
Artisti: Dorothee Albrecht, Marco Bravura, Cristian Ceccaroni, Daniela Comani, Ottavio Fabbri, Verdiano Manzi, Patrizia Merendi, Omar Paolucci, Cristina Rotondaro, Lars Teichmann, Thea Tini, Daniela Tonelli, Paola Turroni
Commissario: Leo Marino Morganti.
Curatore: Valerio Pradal
Comitato scientifico e di selezione delle opere:
A. Bassi
F. Cavallari
M. Comoglio
L. Guerrini
M. G. Riva
R. Stih
C. Tartarin
Gli adolescenti transculturali digital natives : l'esperienza soggettiva tra pratiche e appartenenze
No full textNuove pratiche di comunicazione e processi psico-sociali di costruzione dell'identità negli adolescenti transculturali
No full textIndice analitico
No full textIndice analitico e ragionato del lessico etico filosofico di Lévinas in Etica e Infinito in rapporto con altre opere
EFFECTS OF A PSORIATIC INFLAMMATORY MICROENVIRONMENT ON KERATINOCYTE MORPHOLOGY IN 3D AND 2D BIOLOGICAL EXPERIMENTAL MODELS OF NORMAL HUMAN SKIN
No full textThe interplay between proinflammatory circulating cytokines and keratinocytes is a crucial event in the development and progression of psoriatic lesions. However, the early phases of the pathogenesis of psoriasis are still to be elucidated, in particular regarding the epidermal barrier. A pivotal role is played by tight junctions (TJs), i.e. claudin-mediated intercellular attachment structures, localized in the upper granular layer. A barrier impairment associated to an alteration in TJ proteins is described in psoriasis as a response to a proinflammatory microenvironment. We investigated by immunofluorescence analysis the modulation of the expression of claudin 1 (CLDN-1), a transmembrane integral TJ protein, and of Zonula Occludens 1 (ZO-1), a scaffold plaque protein, after the incubation with MIX, a combination of interleukin (IL)-17, IL-22, IL-23, tumor necrosis factor (TNF)-alpha, for 24 (T24) and 48 (T48) hours. We considered as experimental models the standardized 3D organotypic cultures of normal human skin (n=7) and in vitro cultures of primary normal human keratinocytes (n=3) in basal or differentiating cell growth conditions. On skin bioptic samples, ultrastructural analysis by transmission electron microscopy (TEM) was performed. In control skin samples, CLDN-1 immunopositivity increased from the basal layer upwards, but its expression was early reduced in the basal and suprabasal layers starting from T24 in MIX-incubated group. At this time point, ZO-1 expression in control samples increased gradually, starting from the basal layers towards the epidermal surface and the incubation with MIX induced its immunopositivity in the basal and suprabasal layers. At T24, CLDN-1 expression was unaffected by MIX in undifferentiated and also calcium- differentiated keratinocytes. Unexpectedly, undifferentiated cells relocated ZO-1 at cell-cell contact points after the incubation with MIX, and in calcium-differentiated keratinocytes, ZO-1 synthesis was stimulated, too. By TEM, after MIX incubation, the overall architecture of the epidermal compartment was maintained, but apoptosis and enlargement of intercellular spaces were evident.
The present results strongly suggest that the i) broadening of ZO-1 expression and ii) the downregulation of CLDN-1, typical features of psoriasis, can be induced as early as 24 hours in both models, suggesting that they represent a valid experimental approach.
To complete this study, the effect of this microenvironment on keratinocyte proliferation and differentiation will be investigated, obtaining further insights into the early processes leading to the formation/progression of psoriatic plaques.
Donetti E, Cornaghi L, Gualerzi A, Baruffaldi Preis FW, Prignano F. An innovative three-dimensional model of normal human skin to study the proinflammatory psoriatic effects of tumor necrosis factor-alpha and interleukin-17. Cytokine; 2014; 68:1-8.
Donetti E, Cornaghi L, Arnaboldi F, Ricceri F, Pescitelli L, Maiocchi M, Carriero F, Baruffaldi Preis FW, Prignano F. Epidermal barrier reaction to an in vitro psoriatic microenvironment. Exp Cell Res; 2017; 15:180-188.
Donetti E, Lombardo G, Baruffaldi Preis FW, Cornaghi L, Pescitelli L, Prignano F. 3D skin model to investigate the early epidermal morphological psoriatic features. J Transl Sci; 2019; doi: 10.15761/JTS.1000361
Riva F, Casasco A, Nespoli E, Cornaglia AI, Casasco M, Faga A, Scevola S, Mazzini G, Calligaro A Generation of human epidermal constructs on a collagen layer alone. Tissue Eng; 2007; 13: 2769-79.
Riva F, Casasco A, Casasco M, Calligaro A, Cornaglia AI. Growth and stratification of epithelial cells in minimal culture conditions. Methods Mol Biol; 2010; 585:25-43
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