1,722,482 research outputs found
Le variazioni artificiali del livello idrico primaverile-estivo dell'Adda Morta di Pizzighettone e loro ripercussioni sugli Odonati e sugli Uccelli nidificanti.
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: role of GITR and GILZ, two dexamethasone-induced genes
No full textLaboratory study on asphalt mixture modified by polyacronitrile fibres and reclaimed asphalt planings
No full textn this laboratory study, combined effects of polyacronitrile fibres and reclaimed asphalt planings on performance properties of asphalt mixtures were investigated. Performance properties of six asphalt mixtures in total were comparatively analyzed, always considering a standard mix design concept for asphalt binder courses. Three asphalt mixtures were prepared with fresh materials only: two asphalt mixtures were produced without incorporating fibres, one using unmodified plain binder of the type 50/70 Pen Grade (in the following used as reference mixture and therefore identified as Ref.), the other one using polymer modified binder of the type 40/100-65 Pen Grade (identified as PmB). The third one was a fibre reinforced asphalt mixture (FRAM), composed of 50/70 Pen Grade binder, and 0.15% by total weight of the asphalt mixture of polyacronitrile fibres added directly in the drum to the aggregates. In addition, three more asphalt mixtures were prepared similarly, but 50% of the total mass was replaced by recycled material originating from reclaimed asphalt planings (RAP). These three mixtures containing RAP were identified as Ref.+RAP, PmB+RAP, and FRAM+RAP. All six asphalt mixtures were subjected to performance tests: wheel tracking tests were conducted in the high temperature range to study permanent deformation resistance, indirect tensile tests were conducted at intermediate temperatures to study fatigue resistance, and thermal stress restrained specimen tests were conducted at low temperatures to study resistance to thermal cracking. Test results indicate that asphalt mixture modification by polyacronitrile fibres and reclaimed asphalt planings results in acceptable performance properties, and potentially improves high and intermediate temperature properties
Low-Temperature Properties across the Different Phases: From the Binder to the Mixture
No full textIn this study, a method that can be used to replicate the fine aggregate matrix (FAM) in the field condition as accurately as possible was experimentally validated, and the low temperature performance was measured and evaluated. First, an AC 22 TS mixture is selected as the reference material. The method based on a shift of the grading curve by a mathematic adaptation to the boundary sieve (DFAIB) is used to generate the grading curves of the FAM. Next, small sample beams of asphalt binder, mastic, FAM, and mixture are tested with the bending beam rheometer to evaluate the material's response at low temperatures across the different phases. The results of the BBR study show that the FAM phase has a higher stiffness than binder and mastic with a close behavior to the mixture. The results suggest that the FAM could be potentially adapted for discriminating among different mixtures
Experimental study on the performance properties of bio-based polymer modified binder
No full textIn the present work Tall Oil Pitch (TOP) and SBS were added to a plain binder 30/45 to meet the penetration and softening temperature of a reference polymer modified binder 25/55-55. Performance tests using the Dynamic Shear Rheometer (DSR) and the Bending Beam Rheometer (BBR) were carried out to see if the Bio polymer modified binder can reach similar performances in the high, intermediate and low temperature range to the reference polymer modified binder. The results showed that the chosen formulation can achieve similar rutting and thermal cracking performances, but not similar fatigue performances to the reference binder. Moreover, the effect of adding 50% of RAP binder to the Bio polymer modified binder were investigated. The results indicate better rutting performance and worst fatigue and thermal cracking resistance in comparison to the Bio polymer modified binder
GILZ as a Regulator of Cell Fate and Inflammation.
No full textOne of the human body’s initial responses to stress is the adrenal response, involving the release of mediators that include adrenaline and glucocorticoids (GC). GC are involved in controlling the inflammatory and immune response mechanisms. Of these, the molecular mechanisms that contribute to anti-inflammatory effects warrant more investigation. Previously, we found that GC induced GILZ (glucocorticoid-induced leucine zipper) quickly and widely in thymocytes, T lymphocytes, and other leukocytes. GILZ regulates the activation of cells and is an essential mediator of endogenous GC and the majority of GC anti-inflammatory effects. Further research in this regard could lead to the development of an anti-inflammatory treatment that yields the therapeutic outcomes of GC but without their characteristic adverse effects. Here, we examine the mechanisms of GILZ in the context of GC. Specifically, we review its role in the proliferation and differentiation of cells and in apoptosis. We also examine its involvement in immune cells (macrophages, neutrophils, dendritic cells, T and B lymphocytes), and in non-immune cells, including cancer cells. In conclusion, GILZ is an anti-inflammatory molecule that could mediate the immunomodulatory activities of GC, with less adverse effects, and could be a target molecule for designing new therapies to treat inflammatory diseases
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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