1,721,113 research outputs found
Synthesis of D- and L-2-Amino-2-deoxyarabinose and 1,4-Dideoxy-1,4-iminolyxitol by (C2 + C3)-Nitroaldol Addition with 2-O-Benzylglyceraldehyde — Cyclization of N-Protected 1-Amino-4-pentene-2,3-diols to lyxo-Configurated Deoxyimino Sugars (cis-Dihydroxypyrrolidines); Synthesis of Potential Glycosidases Inhibitors — Diastereoselective Conjugate Addition of Ammonia in the Synthesis of Chiral Pyrrolidines.
C-Arylation at the Anomeric Centre of Sugars by Bromomagnesium Phenolates: Synthesis of 1,1- and 5,5-Bis-(2-Hydroxyaryl)-C-Glycosyl Derivatives.
Synthesis of 1-(2-Hydroxyaryl)-1,2,3-propanetriol and 1-(2-Hydroxyaryl)-2-amino-1,3-propanediol Derivatives of either threo or erythro Configuration.
Vinylogous aldol reaction of heterocyclic silyloxy dienes. Application in synthesis
A versatile, readily accessible triad of 2-enoxy silane synthons derived from furan, pyrrole, and thiophene is presented. These heterocycles, in reacting with carbonyl and carbonyl-related acceptors, act as vinylogous nucleophile modules, giving rise to diverse, functionality-rich, γ-substituted α,β-unsaturated carbonyl constructs. These, in turn, are invaluable platforms onto which further functional elements and chirality may be introduced. A couple of appealing applications-the variable construction of a repertoire of carbasugars and a library of annonaceous acetogenin segments-have been chosen to illustrate the viability of this vinylogous aldol approach
Use of Dihydroxyacetone Phosphate Dependent Aldolases in the Synthesis of Deoxyazasugars.
Furan-, Pyrrole-, and Thiophene-Based Siloxydienes en route to Carbohydrate Mimics and Alkaloids
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