1,721,208 research outputs found
Scalp expansion: Surgical considerations and possible future directions
No full textIntroduction: Repairing large scalp defects has always been a difficult task for plastic surgeons. This is because the requirements of such procedures are two-fold: sufficient soft-tissue coverage is required, and to obtain a satisfactory aesthetic outcome, a sufficient number of covering hairs should be ideally provided. Materials and Methods: Based on the author's experience in this repair technique over a 20-year period, this article presents some technical details of scalp expansion, surgical refinements and possible directions for further technical advancement. Results: Data and details on relevant scalp anatomy, expander choice, expander placement, subgaleal undermining, galeotomies and acute scalp expansion are provided. Conclusions: The author hopes that the above-mentioned details may be of some utility in the complex field of scalp expansion
A small new idea for the training of plastic surgery residents
No full textBACKGROUND: Today, learning the craft of surgery is threatened by several factors, including the scarce availability of cadaver and animal models. METHODS: We propose the use of human limbs and tissues removed during commonly performed surgical procedures (e.g., lower limb amputations and abdominoplasties) as training models for plastic surgery residents. Lower limbs could be used for learning to design and harvest the majority of flap types in this region, while cutaneous lozenges from abdominoplasties could be used for training on most types of local skin flaps. RESULTS: The above-described models are routinely used by trainees in our residency program with enthusiasm and proficiency. Professors have found these models ideal for improving surgical education efficiency. CONCLUSIONS: In our opinion, the described models are valid adjuncts to currently adopted training tools in the field of surgery. They can help minimize costs as well as ethical and organizational problems, and offer training quite close to real operative situations
Frontal Endoscopic Myotomies for Chronic Headache.
No full textRecent insights into the pathogenesis of migraine headache
substantiate a neuronal hyperexcitability and inflammation
involving compressed peripheral craniofacial nerves, and these
trigger points can be eliminated by surgery. The aim of this study
was to describe a modified, innovative, minimally invasive endoscopic
technique to perform selective myotomies of corrugator
supercilii, depressor supercilii, and procerus muscles, which turned out to be an effective therapy for migraine and tension-type
headaches.
Forty-three patients (18–75 years) who experienced 15 or more
frontal migraine headaches without aura, tension-type headaches, or
new daily persistent headaches each month were enrolled in the
study between 2011 and 2013. Of 43 patients, 15 were followed for
2 years. Fourteen patients (93.3%) reported a positive response to
the surgery: 5 (33.3%) observed complete elimination, 9 (60%)
experienced significant improvement (at least 50% reduction in
intensity or frequency), and 1 patient (6.6%) did not notice any
change in their headaches. A statistically significant difference was
found between our protocol compared with currently performed,
more invasive technique (odds ratio, 1.9; 95% confidence interval,
1.151–3.13).
According to our data, the modified endoscopic procedure leads
to better results, compared to previous techniques, together with
eliminating the need for general anesthesia, reducing the invasiveness
of the procedure and the number of postoperative scars
Analysis of the European legal regulation on advanced therapy products: A guide to possible clinical applications of ASCS
No full textMesenchymal stem cells derived from adipose tissue are cells with high differentiation capacity, high bioavailability and very low morbidity of the collection site, making these cells ideal for regenerative medicine therapies. The high interest of recent years towards this promising resource has made European legislative adjustment indispensable. Such products must be subject to specific legal rules on their production, distribution and use with the primary purpose of protecting public health. The purpose of this study was to describe and analyze existing European legislation to provide guidance on the correct definitions and isolation or manipulation techniques allowed for all practitioners involved in regenerative medicine
Scalp Surgery: Quantitative Analysis of Follicular Unit Growth
No full textBackground: Over the years, different kinds of hair transplantation have
been compared in an attempt to overcome male pattern alopecia and, at
the same time, maximize both the survival and growth rate of grafted hair.
In this study, we have assessed the survival and growth rate of follicular
units (FU) in an in vitro model, as compared with that of conventional hair
micrografts, to experimentally evaluate and elaborate on the differences
between these 2 approaches in hair transplantation procedures.
Methods: Group A (control; n = 100 follicles) was composed of hair micrografts,
whereas FUs were assigned to Group B (experimental; n = 100
follicles, n = 35 FUs). Each group was cultured for a period of 10 days; the
total stretch of follicles was measured soon after the harvest and 10 days
later. The Kruskal-Wallis one-way analysis of variance on ranks test was used
to perform statistical analysis.
Results: The growth rate of follicles from Group A (mean 10-day shaft
growth rate = 0.30 mm) proved to be statistically different compared with
that of Group B (mean 10-day shaft growth rate = 0.23 mm). Conversely,
our data did not show any significant difference between the survival rate
of hair grafts from these 2 groups.
Conclusions: Our data highlighted a reduced FU shaft growth compared
with that of hair micrografts, corroborating, to a certain extent, the
hypothesis that a significant amount of adipose tissue surrounding the
follicle
included in the graft may result in an inadequate nourishment
supply to follicular cells
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