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The IAAF’s hyperandrogenism regulations suspended
No full textOn 27 July, the Court of Arbitration for Sport (‘CAS’) delivered a landmark ruling on the regulation of gender in sport. The decision explores how the categorisation of sport on the basis of sex can be best reconciled with the “biological reality” that human sex cannot necessarily be divided so clearly. Dr. Seema Patel, Senior Lecturer at Nottingham Trent University, Deputy Director of the Centre for Sports Law and author of ‘Inclusion and Exclusion in Competitive Sport: Socio-Legal and Regulatory Perspectives,’ reviews the case and suggests that sport regulation must be cautious of traditional criteria to determine eligibility in sports
Author interview: Q and A with Dr Ian Sanjay Patel on we’re here because you were there: immigration and the end of empire
No full textIn this author interview, we speak to Dr Ian Sanjay Patel about his new book, We’re Here Because You Were There: Immigration and the End of Empire, which explores post-war immigration laws, the afterlives of British imperial citizenship and related attempts to reimagine and rejuvenate British imperialism after 1945. Contributing to transnational histories of decolonisation, the book also explores the interconnections between human rights, post-war migration and international diplomacy. Author Interview with Dr Ian Sanjay Patel, author of We’re Here Because You Were There: Immigration and the End of Empire. Verso. 2021
Gold nanoparticles explore cells: cellular uptake and their use as intracellular probes
No full textUnderstanding uptake of nanomaterials by cells and their use for intracellular sensing is important for studying their interaction and toxicology as well as for obtaining new biological insight. Here, we investigate cellular uptake and intracellular dynamics of gold nanoparticles and demonstrate their use in reporting chemical information from the endocytotic pathway and cytoplasm. The intracellular gold nanoparticles serve as probes for surface-enhanced Raman spectroscopy (SERS) allowing for biochemical characterisation of their local environment. In particular, in this work we compare intracellular SERS using non-functionalised and functionalised nanoparticles in their ability to segregate different but closely related cell phenotypes. The results indicate that functionalised gold nanoparticles are more efficient in distinguishing between different types of cells. Our studies pave the way for understanding the uptake of gold nanoparticles and their utilisation for SERS to give rise to a greater biochemical understanding in cell-based therapies
Raman Spectroscopy of pure and (Nb+In) co-doped TiO2 single crystals
No full textThis research project focused on the study of pure TiO2 rutile crystals and rutile crystals that were 2% co doped with Niobium and Indium TiO2 (2-NITO). There has been a growing interest in co-doped TiO2 due to recent papers published on its “colossal permittivity” in the lower frequency range of 10^2 to 10^6 Hz. The goal of this study was to analyze the impact of co-doping on the Raman modes by using Raman spectroscopy. To determine the Raman shift and Half width at half max from the raman data, the Lorentz fit analysis was applied
The further assessment of a handheld Raman spectroscopy probe for the intraoperative diagnosis of axillary lymph nodes in breast cancer
No full textAxillary sentinel lymph node biopsy plays an important role in breast cancer management
in determining further surgical and medical treatment options. Intraoperative assessment of
the sentinel lymph node might allow immediate axillary surgery, which would incur
benefits to both the patient and healthcare trusts. A handheld Raman spectroscopy probe
has already been shown to be a comparable option for intraoperative assessment through
previous published and unpublished studies, delivering a sensitivity of up to 92% and
specificity of up to 99%.
This research aims to define further the role of the hand-held Raman spectroscopy probe as
an accurate, rapid and non-destructive technique for intra-operative axillary node
assessment, making it a strong competitor in the clinical market. It also looks to improve
the sensitivity of the probe by altering the methodology used in previous studies.
122 lymph node halves were collected intraoperatively from 37 patients diagnosed with
breast cancer and spectra measured using a commercially available handheld Raman
spectroscopy probe. Spectra were then fed into a specialist software programme and
analysed using principal component fed linear discriminant analysis trained by
histopathology results.
A “2 group” training model defining the probe‟s ability to distinguish between benign and
malignant tissue produced an overall performance of 86.4%, with a sensitivity of 71% and
specificity of 91%.
The results were not as impressive as previous studies. This was possibly due to a broken
probe, leading to four different phases of measurements (original probe/failing
probe/temporary replacement/mended probe). Secondly a smaller, less balanced data set, in
terms of spectra per pathology group, was collected and there appeared to be more
fluorescence in some of the data which may have originated from varying blue dye
injection protocols. However, that said further research using a robust, high specification
system may help establish its role as a reliable assessment tool intraoperatively as well as
a non-invasive means of assessing lymph nodes in the initial assessment clinic
A chirped, pulsed laser system and magneto-optical trap for rubidium
No full textThis thesis covers the construction and characterisation of a magneto-optical trap (MOT) for 85Rb from the very beginning. It details both the optical and mechanical aspects from laser diode assembly, tuning and stabilisation to the preparation and assembly of the vacuum system. The MOT construction forms the first goal of the project, the second was to develop a laser system capable of producing custom programmable, amplitude modulated and frequency chirped pulses (on the tens of microseconds timescale) from a continuous wavesource. This involved developing software and computer control for several arbitrary signal generators linked to drivers for acousto-optic and electro-optic modulators. This chirped, pulsed laser system will be used to perform state manipulations on the 85Rb MOT cloud using two-photon Raman transitions in an adiabatic rapid passage regime. The chirped pulse system was initially tested with a rubidium vapour cell in an attempt to perform atomic interferometry that would produce spatial interference fringes along the length of the cell. However, due to the beam power requirements, the beam diameter together with the large Doppler shift at room temperature meant these fringes were not seen and so the vapour cell was replaced with the cold atom cloud in the MOT. Two-photon experiments were attempted with the MOT cloud using the chirped pulse system, however despite greatly improved laser power and detection efficiency, the signal indicating ground state population transfer via a two-photon interaction was not seen. The results indicate that the hyperfine-ground state splitting frequency has been shifted due to the proximity of the ion pump magnet to the vacuum system. Presently, efforts are being directed towards searching for the correct frequency
Intelligent transportation systems (ITS) operational support contracts implementation plan / submitted by Raman K. Patel.
No full textEmbedded in the Body: the Poetry, History and Politics of Migritude with Shailja Patel (2021-02-25)
No full textOnline discussion, reading and Q&A; Thursday, February 25 at 4:00PM CST; Shailja Patel is the bestselling author of Migritude, taught in over 100 colleges and universities worldwide. Patel's poems have been translated into 17 languages, and been featured in the Smithsonian. The Nobel Women's Initiative honored her with a Global Feminist Spotlight. She is currently a Research Associate at Five College Women's Studies Research Center.Women, Gender & Sexuality Studies program; Alworth Institute for International Studies; Department of Anthropology, Sociology & Criminology; English program; Writing Studies programPatel, Shailja. (2021). Embedded in the Body: the Poetry, History and Politics of Migritude with Shailja Patel (2021-02-25). Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/220654
Aphelocheirus Westwood 1833
No full textSubgenus Aphelocheirus Westwood, 1833 Type species. Naucoris aestivalis Fabricius, 1794; by original designation.Published as part of PATEL, RAMAN, RANA, RAJENDRA SINGH, NEL, ANDRÉ & ALI, ASHIF, 2023, The oldest aquatic aphelocheirid bug (Heteroptera, Nepomorpha) from the lower Eocene of India, pp. 250-254 in Palaeoentomology 6 (3) on page 251, DOI: 10.11646/palaeoentomology.6.3.7, http://zenodo.org/record/807306
Thermal Stability of m-Xylene-formaldehyde Resin and its Derivative
No full textDepartment of Chemistry, Sardar Patel University, Vallabh Vidyanagar-388 120
Manuscript received 23 June 1983, accepted 27 October 1983
Thermal Stability of m-Xylene-formaldehyde Resin and its Derivativ
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