5,124 research outputs found
Dynamics of Nanodroplets on Vibrating Surfaces
No full textThis data folder contains the output data from all molecular dynamics simulations carried out in this paper: Pillai, R, Borg, M & Reese, J 2018, 'Dynamics of nanodroplets on vibrating surfaces' Langmuir. DOI: 10.1021/acs.langmuir.8b02066 .This data folder contains the output data from all molecular dynamics simulations carried out in this paper
Stringa architettonica e stringa urbana. Un progetto possibile
No full textPubblicazione del progetto teorico-sperimentale “La ‘stringa urbana’, 2004”, presentato da Rosalba Pillai.
Compare anche “Pensare architettonico” (2003), aggiornato con la teorizzazione della nozione di “stringa urbana” (2004). Elaborato scritto-grafico costruito attraverso la ricognizione, in forma criptata, di alcuni frammenti di teoria personale, tra cui le nozioni di “stringa architettonica” (1971) e di “stringa urbana” (2004)
Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections.
No full textBACKGROUND: Monitoring resistance phenotypes for Plasmodium falciparum, using in vitro growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resistance to artemisinins.
METHODS: Plasmodium falciparum isolates cultured from 28 returning travellers diagnosed with malaria were assessed for sensitivity to artemisinin, artemether, dihydroartemisinin and artesunate and findings related to mutations in pfatp6 and pfmdr1.
RESULTS: Resistance to artemether in vitro was significantly associated with a pfatp6 haplotype encoding two amino acid substitutions (pfatp6 A623E and S769N; (mean IC50 (95% CI) values of 8.2 (5.7 - 10.7) for A623/S769 versus 623E/769 N 13.5 (9.8 - 17.3) nM with a mean increase of 65%; p = 0.012). Increased copy number of pfmdr1 was not itself associated with increased IC50 values for artemether, but when interactions between the pfatp6 haplotype and increased copy number of pfmdr1 were examined together, a highly significant association was noted with IC50 values for artemether (mean IC50 (95% CI) values of 8.7 (5.9 - 11.6) versus 16.3 (10.7 - 21.8) nM with a mean increase of 87%; p = 0.0068). Previously described SNPs in pfmdr1 are also associated with differences in sensitivity to some artemisinins.
CONCLUSIONS: These findings were further explored in molecular modelling experiments that suggest mutations in pfatp6 are unlikely to affect differential binding of artemisinins at their proposed site, whereas there may be differences in such binding associated with mutations in pfmdr1. Implications for a hypothesis that artemisinin resistance may be exacerbated by interactions between PfATP6 and PfMDR1 and for epidemiological studies to monitor emerging resistance are discussed
Pseudirona laeopsi Pillai 1964
No full textPseudirona laeopsi Pillai, 1964 Pseudirona laeopsi Pillai, 1964: 222–223, fig. 6.— Trilles, Ravichandran & Rameshkumar, 2011: 453. Type and type locality. Pillai (1964) collected specimens from the gill chamber of Laeops macrophthalmus (Alcock, 1889) from Anchuthengu, Trivandrum, Kerala Coast, Arabian Sea. The author reported that the holotype female is deposited in the Indian Museum but the detail of the accession number is not available in the original description. The present museum inquiries, at the Indian museum, failed to recover any material for P. laeopsi and it seems that the types were either not submitted or it was lost. Remarks. Pseudirona laeopsi was not reported since its original description by Pillai (1964). Pseudirona laeopsi can be distinguished from other cymothoid species by the extremely spiny and setose appendages. Until now the identification of this species is based only on Pillai’s original description and it needs an accurate redescription. Distribution. Trivandrum, Kerala Coast, India (type locality) (Pillai 1964). Host. Known only from type host Laeops macrophthalmus (Alcock, 1889) (Pillai 1964).Published as part of Ravichandran, S., Vigneshwaran, P. & Rameshkumar, G., 2019, A taxonomic review of the fish parasitic isopod family Cymothoidae Leach, 1818 (Crustacea: Isopoda: Cymothooidea) of India, pp. 1-99 in Zootaxa 4622 (1) on page 72, DOI: 10.11646/zootaxa.4622.1.1, http://zenodo.org/record/337989
Acropora stoddarti Pillai & Scheer 1976
No full textAcropora stoddarti Pillai & Scheer, 1976 Acropora stoddarti Pillai & Scheer, 1976: 27, pls 5–6. Type locality. Addu Atoll, Maldives (holotype HSMD). MTQ Holdings. Maldives: topotypes G46421–23 Addu Atoll, Maldives. Species group: divaricata. Description. Colony outline: determinate, predominantly arborescent table. Branches: tertiary branching order absent; length: 25–50 mm; diameter: 10.0–19.9 mm, 50/50 axial/ radial; tapering; radial crowding: some touching; axial/radial ratio:>1:10. Axial corallites: three synapticular rings; not porous; outer diameter 1.9–2.5 mm; inner diameter 0.7–1.3 mm; primary septa to ½ R. Radial corallites: medium; three synapticular rings; one size or graded; inner wall developed; shape: nariform; round openings; primary septa to 1/3 R. Coenosteum: same on and between radials: reticulate to reticulocostate, spinule shape: single point or forked. Taxonomic note. These specimens at the type locality (Gan I. lagoon, Addu Atoll, Maldives). We have taken A. stoddarti out of the synonymy with A. divaricata (as given in Wallace 1999): however its precise identity remains elusive. While all specimens share similarities with A. divaricata, there is a high degree of variability, amongst the three specimens at hand, in the width of branches, which range from broad and strap-like to slender and tapering. The colony illustrated bears the greatest similarity to syntype X2:31-24 of Pillai and Scheer (1976). Further literature: Veron (2000) (some of the illustrated specimens may not be A. stoddarti).Published as part of Wallace, Carden C., Done, Barbara J. & Muir, Paul R., 2012, Revision and catalogue of worldwide staghorn corals Acropora and Isopora (Scleractinia: Acroporidae) in the Museum of Tropical Queensland, pp. 1-258 in Memoirs of the Queensland Museu Nature 57 on page 198, DOI: 10.5281/zenodo.216351
Acropora eibli Pillai & Scheer 1976
No full textAcropora eibli Pillai & Scheer, 1976 Acropora eibli Pillai & Scheer, 1976: 33, pl. 10. Type locality. Rasdu Atoll, Maldives (holotype HSMD). MTQ Holdings. Maldives: G60011–14 topotypes from Rasdoo Atoll, Maldives. Species group: not determined. Description. Colony outline: determinate, predominantly plate. Branches: tertiary branching order absent; length: 25–50 mm; diameter: 5.0–9.9 mm, 50/50 axial/radial, tapering; radial crowding: not touching; axial/radial ratio:>1:10. Axial corallites: three synapticular rings; not porous; outer diameter 1.4–1.6 mm; inner diameter 0.6–0.7 mm; primary septa to ½ R. Radial corallites: medium; three synapticular rings; one size or graded; inner wall developed; shape: nariform; openings: round to oval; primary septa to ¾ R. Coenosteum: same on and between radials: reticulate, spinule shape: forked. Taxonomic note. This species is taken out of the synonymy of A. tenella, following examination of topotypic specimens.Published as part of Wallace, Carden C., Done, Barbara J. & Muir, Paul R., 2012, Revision and catalogue of worldwide staghorn corals Acropora and Isopora (Scleractinia: Acroporidae) in the Museum of Tropical Queensland, pp. 1-258 in Memoirs of the Queensland Museu Nature 57 on page 62, DOI: 10.5281/zenodo.216351
Acoustothermal atomization of water nanofilms
No full textThis data folder contains the output data from all molecular dynamics simulations carried
out in this paper: Pillai et al. https://doi.org/10.1103/PhysRevLett.121.104502
A Specialized Role for the Pacific Herring Egg Chorion in Sperm Motility Initiation
No full textProceedings of the International Congress on the Biology of Fishes are not peer-reviewed or edited and should not be cited in the same manner as original, peer-reviewed publications.The micropyle region of the eggs of Pacific herring (Clupea pallasi) has been shown to play an active role in the activation of herring sperm (Yanagimachi and Kanoh, 1953; Yanagimachi, 1957; Yanagimachi et al., 1992; Pillai, et al., 1993; Griffin et al., 1996. Unlike the sperm of most organisms, herring sperm are virtually immotile at the time of spawning, however, contact with the micropyle region of the herring egg initiates sperm motility. Our laboratory has focused on the basic mechanisms of the above phenomenon during herring gamete interaction, as well as the role of environmental factors in modulating fertilization
Rudiments of materials science
No full textWriting a comprehensive book on Materials Science for the benefit of undergraduate courses in Science and Engineering was a day dream of the first author, Dr. S.O. Pillai for a long period. However, the dream became true after a lapse of couple of years. Lucid and logical exposition of the subject matter is the special feature of this book
Vayala Vasudevan Pillai: A Playwright Par Excellence
No full textVasudevan Pillai is an eminent theatre personality who made significant contributions to the development of indigenous theatre concepts particularly to Malayalam theatre. His spirit of inquiry and quest for knowledge in performing arts were so high that he travelled far and wide and interacted with world renowned dramatists like Antonin Artaud, Jerzy Grotowski, Richard Schechner and Bertolt Brecht which gave him new insights into the world of theatre. Though he had acquired the technical skills of different theatres he never tried to imitate those into the native theatre. Following the footsteps of his mentor G. Sankara Pillai, who set a direction to his dramatic genius Vasudevan Pillai attempted to explore the latent indigenous theatre tradition of Kerala. However, Western theatrical techniques had an influence in shaping his dramatic concepts. Though he has a deep knowledge of the philosophy and techniques of both Eastern and Western theatres, he has not tried to deliberately fit them into his composition and presentation. He preached and penned what he thought proper. Thus he became the voice and expression of truth and humanity in Malayalam theatre
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