1,721,035 research outputs found
Il ruolo del sistema nazionale di allerta precoce nella tutela della salute pubblica: strategie istituzionali e contributo tossicologico-forense per il contrasto alla diffusione delle nuove sostanze psicoattive
Lo scopo della presente tesi è di esporre il ruolo e le attività svolte dal Sistema Nazionale di Allerta Precoce (SNAP), istituito nel 2009 dal Dipartimento per le Politiche Antidroga (DPA) e coordinato dal punto di vista operativo e scientifico, a partire da giugno 2016, dall’Istituto Superiore di Sanità (ISS).
Si descrive l’organizzazione del flusso di informazioni e i dati epidemiologici relativi alla diffusione delle nuove sostanze psicoattive (NSP) sul territorio europeo e nazionale, attraverso le segnalazioni precoci della loro comparsa sul mercato clandestino e la tempestiva comunicazione di eventuali stati di allerta relativi a fenomeni potenzialmente pericolosi per la salute pubblica strettamente correlati al consumo di questi composti.
Obiettivo della tesi è anche l’illustrazione delle strategie messe in atto per far fronte alla rapida diffusione delle NSP nella Unione Europea e sul territorio italiano, presentando il supporto biotossicologico fornito dalla Unità Operativa di Tossicologia Forense dell’Università Sapienza di Roma (UO di Biotossicologia), nell’ambito delle attività del Sistema di Allerta.
A tale proposito verrà descritto il ruolo della UO di Biotossicologia nella revisione delle Comunicazioni provenienti dall’Osservatorio Europeo sulle Droghe e sulle Tossicodipendenze e la preparazione delle Informative relative ai sequestri operati dalle forze dell’ordine su territorio nazionale. Verrà inoltre esposto il contributo tecnico analitico offerto dalla suddetta Unità Operativa nei casi di accertamenti tossicologici effettuati su materiale non biologico oggetto di sequestro. Infine verranno presentate le revisioni sistematiche della letteratura internazionale, realizzate dall’Unità Operativa di Tossicologia Forense in merito alle NSP di maggiore diffusione e pericolosità sul territorio nazionale, sulla base dell’esperienza tecnico scientifica maturata durante la collaborazione con lo SNAP.
Capitolo 1: viene illustrata l’organizzazione del Sistema Nazionale di Allerta Precoce (SNAP) ed il ruolo cruciale che tale piattaforma riveste nella tutela della salute pubblica, coordinando lo scambio rapido di informazioni tra l’Osservatorio Europeo sulle droghe e sulle tossicodipendenze, le Forze dell’Ordine che operano i sequestri su territorio nazionale ed i Centri Collaborativi (ospedali, dipartimenti di emergenza, Ser.D.), al fine di facilitare la precoce individuazione di nuove sostanze psicoattive sul mercato clandestino e supportare le attività medico-sanitarie nel trattamento in emergenza di soggetti in stati di intossicazione acuta da NSP.
Capitolo 2: si introduce il concetto di nuova sostanza psicoattiva, effettuando una disamina della struttura chimica delle principali classi di appartenenza di questi composti ed approfondendo la delicata problematica dello stato di emergenza socio-sanitaria connesso al loro consumo.
Capitolo 3: viene descritto il supporto biotossicologico e tecnico analitico che l’Unità Operativa di Tossicologia Forense offre all’interno dello SNAP nella supervisione della documentazione e degli eventi che sono oggetto di attività del Sistema, sia a livello europeo che nazionale. Vengono, inoltre, presentate le revisioni sistematiche della letteratura internazionale realizzate dall’UO, in merito alle NSP maggiormente diffuse nel nostro Paese e che rappresentano ad oggi un grave rischio per la salute pubblica.
Capitolo 4: è dedicato alle conclusioni del lavoro di tesi, alle criticità del complesso sistema dedicato alla prevenzione ed alla lotta alla diffusione delle NSP ed agli obiettivi futuri, prevalentemente focalizzati sulla messa a punto di nuovi strumenti scientifici e legislativi sempre più efficaci per affrontare e combattere l’emergenza sociale e medico-sanitaria causata dalla indiscriminata espansione di queste nuove sostanze
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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