651 research outputs found
Production and characterization of a monoclonal antibody that recognizes 6,4,4'-trimethylangelicin-DNA photoadducts
No full textExperimental T cells immunotherapy by tumor-loaded ECP-generated dendritic antigen presenting cells
No full textReal line bundles on spheres
No full textIn a recent paper the author proved a classification theorem for Atiyah-real vector bundles on spaces with free involutions. This result is now applied to the group of Atiyah-real line (i.e., one-dimensional) bundles on spheres, denoted
L
R
(
S
n
)
{L_R}({S^n})
. It is proved that such bundles are classified by maps into a complex quadric
Q
C
n
Q{C^n}
. Using this classification it is proved that
L
R
(
S
1
)
=
0
{L_R}({S^1}) = 0
and that for
n
≧
3
n \geqq 3
the groups are all isomorphic.</p
Characterization of monoclonal antibody specificity using oligonucleotides containing a single 8-MOP crosslink.
No full textMotion detection technology as a tool for cardiopulmonary resuscitation (CPR) quality improvement
No full textThe most popular method of training in basic life support and AED remains instructor-led training courses. Recent reviews provide good evidence to support alternative methods of training including lay instructors, self-directed learning (web, video, poster) and CPR feedback/prompt devices
A simultaneous XMM-Newton and BeppoSAX observation of the archetypal broad line Seyfert 1 galaxy NGC 5548
No full textWe report the spectral analysis of a long XMM-Newton observation of the well-studied, moderate luminosity broad line Seyfert 1 galaxy NGC 5548. The source was at an historically average brightness and we find the hard (3-10 keV) spectrum can be well fitted by a power law of photon index Gammasimilar to1.75, together with reflection. The only feature in the hard X-ray spectrum is a narrow emission line near 6.4 keV, with an equivalent width of similar to60 eV. The energy and strength of this line are consistent with fluorescence from 'neutral' iron distant from the central continuum source. We find no evidence for a broad Fe K line, with an upper limit well below previous reports, suggesting the inner accretion disc is now absent or highly ionized. The addition of simultaneous BeppoSAX data allows the analysis to be extended to 200 keV, yielding important constraints on the total reflection. Extrapolation of the hard X-ray power law down to 0.3 keV shows a clear 'soft excess' below similar to0.7 keV. After due allowance for the effects of a complex warm absorber, measured with the XMM-Newton RGS, we find that the soft excess is better described as a smooth upward curvature in the continuum flux below similar to2 keV. The soft excess can be modelled either by Comptonized thermal emission or by enhanced reflection from the surface of a highly ionized disc
Correlated X-ray/ultraviolet/optical variability in the very low mass AGN NGC 4395
No full textWe report the results of a 1-yr Swift X-ray/ultraviolet (UV)/optical programme monitoring the dwarf Seyfert nucleus in NGC4395 in 2008-2009. The UV/optical flux from the nucleus was found to vary dramatically over the monitoring period, with a similar pattern of variation in each of the observed UV/optical bands (spanning 1900-5500 Å). In particular, the luminosity of NGC4395 in the 1900 Å band changed by more than a factor of 8 over the monitoring period. The fractional variability was smaller in the UV/optical bands than that seen in the X-rays, with the X-ray/optical ratio increasing with increasing flux. Pseudo-instantaneous flux measurements in the X-ray and each UV/optical band were well correlated, with cross-correlation coefficients of ≥0.7, significant at 99.9per cent confidence. Archival Swift observations from 2006 sample the intra-day X-ray/optical variability on NGC4395. These archival data show a very strong correlation between the X-ray and b bands, with a cross-correlation coefficient of 0.84 (significant at >99per cent confidence). The peak in the cross-correlation function is marginally resolved and asymmetric, suggesting that X-rays lead the b band, but by ≤1h. In response to recent (2011 August) very high X-ray flux levels from NGC4395 we triggered Swift target of opportunity observations, which sample the intra-hour X-ray/UV variability. These observations indicate, albeit with large uncertainties, a lag of the 1900 Å band behind the X-ray flux of ∼400s. The tight correlation between the X-ray and UV/optical lightcurves, together with the constraints we place on the lag time-scale, is consistent with the UV/optical variability of NGC4395 being primarily due to reprocessing of X-ray photons by the accretion disc
Developing Epistemological Values in Students using Microsoft Excel(R) as a Software-Based Support Tool
No full textThis thesis project addresses student epistemological values through technology and independent laboratories. The literature provides evidence that students show greater learning when they are prompted to reflect and develop these epistemological values (Davis, 2003 Demetriadis et al., 2011; Edelson & Kyza, 2005; Reiser & Sandoval, 2004). Furthermore, in conjunctions with research that supports prompting, other research advocates for the development and use of more modern technologies (Edelson & Kyza, 2005; Keengwe et al., 2008; Kuhn, 2001; Maddux, 1998). As such, my culmination project consists of two virtual “lab notebooks.” These notebooks are made using Microsoft Excel® and consist of several quasi-intelligent macros that not only provide instant feedback, but also help guide students through the experimental process in a way akin to inquiry. While a completed series of these notebooks would show more scaffolding as the year progressed, the two I have created represent a student’s first and last experience with these notebooks
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