881 research outputs found
(l to r:) Pfc\u27s Bruce Paulock, Jimmy Hetzer, Mickey Rooney, Unidentified, Germany, 1945
No full text(l to r:) Pfc Bruce Paulock, Pfc Jimmy Hetzer, Pfc. Mickey Rooney, unidentified, Germany, 1945, b&w. Back reads: Left to right: Pfc Bruce Paulock, Pft Jimmy Hetzer, Pfc Mickey Rooney Pilot of plane that flew them back to join their units in various parts of Germany. Taken at Bad Wildingen Germany June 11, 1945.https://mds.marshall.edu/bliss_enslow_add/1089/thumbnail.jp
Detection of Gender Differences in Incomplete Revascularization after Coronary Artery Bypass Surgery Varies with Classification Technique
No full textOertelt-Prigione S, Kendel F, Kaltenbach M, Hetzer R, Regitz-Zagrosek V, Baretti R. Detection of Gender Differences in Incomplete Revascularization after Coronary Artery Bypass Surgery Varies with Classification Technique. BioMed Research International. 2013;2013: 108475
Impact of gender and age on risk factor distribution and health perception: evaluation in a prospective population with heart disease
No full textOertelt-Prigione S, Kendel F, Lehmkuhl E, Hetzer R, Regitz-Zagrosek V. Impact of gender and age on risk factor distribution and health perception: evaluation in a prospective population with heart disease. Journal of Public Health. 2014;22(3):219-226
Weaning from mechanical support after complete recovery in patients with ideopathic dilated cardiomyopathy
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Long-term mechanical circulatory support: The Berlin experience IN CHILDREN - TOWARDS MYOCARDIAL RECOVERY - PERMANENT
No full textLong-term mechanical circulatory support: The Berlin experience IN CHILDREN - TOWARDS MYOCARDIAL RECOVERY - PERMANENT
No full textThe Development of laminated wood constructions considering particulary the inventions by Otto Hetzer - a contributions to the history of building technique
No full textZiel der Arbeit ist die Ermittlung des Einflußes Otto Hetzers auf die Entwicklung des Holzleimbaus. Dabei werden vor allem die ersten Holzleim-Bauwerke in der Zeit bis 1918 umfassend dargestellt. Die Recherchen stützen sich hauptsächlich auf die damaligen Veröffentlichungen, wobei die noch bestehenden Gebäude vom Verfasser vor Ort untersucht und dokumentiert wurden. Karl Friedrich Otto Hetzer entwickelte den Holzleimbau unter Verwendung von Kaseinleim zu industrieller Reife. Nach der Entwicklung von Dachkonsruktionen und Typenhallen gelang auf der Weltausstellung 1910 in Brüssel der technische Durchbruch mit der Ausstellungshalle der Deutschen Reichsbahn, welche mit 43 Meter Spannweite Maßstäbe setze. Nachfolgende Bogenbinderhallen vergrößerten immer mehr die Spannweiten bis über 100m. Als Weiterentwicklung sind vor allem die zeltartigen Konstruktionen zu nennen, die eine ideale Tragwirkung als zugbeanspruchte Konstruktion ermöglichen.The aim of the projekt is to determine the influence of Otto Hetzer of the development of laminated wood constructions. The first buildings with laminated wood constructions in the time until 1918 are presented comprehesively. The research is based mainly on contemporary publications and still existing buildings having been investigated in situ and dokumnented by the author. Karl Frierich Otto Hetzer brought laminated wood constructions to their industrial height by using casein glue. After the development of roofconstructions and type buildings he made the technical breakthrough 1910 at the world exhibition in Brussls. With the exhibitions Hall of the Deutsche Reichsbahn presenting a span of 43 meters, he set a new standard. With foowing arched halls it became possible to extend the spans to more than 100 meters. Especially the development of domed halls with three dimensional multi component systems and tetrahedron constructions should be mentioned. These constructions enable an ideal structure system mainly under tension
Six1 is down-regulated in end-stage human dilated cardiomyopathy independently of Ezh2
No full textackground Recently, it was shown that a knock-out (KO) of the polycomb histone methyltransferase Ezh2 leads to cardiac hypertrophy in mice, which was driven by the homeodom ain transcription factor Six1. Here, we analyzed the expression of Six1 and its regulating factor Ezh2 in cardiac tissue of pa- tients with end-stage dilative cardiomyopathy (DCM). Methods Tissue samples of patients with end-stage DCM (n = 35) were com- pared with control s (n = 12) for the protein expression of Ezh1, Ezh2, Six1, and a marker of protein expression p70S6K. Results Contrary to the Ezh2-KO mouse model, we found a down-regulation of Six1 (26%) and an up-regulation of Ezh2 (76%) in DCM hearts, (both P < 0.05). Expression of Ezh2 and Six1 did not correlate in human tissue (DCM: r 2 : 0.03, P = 0.31 and donor: r 2 : 0.05, P = 0.45). Expression of Six1 weakly correlated with left ventricula r end-systolic diameter and fractional shortening. In DCM, Six1 also showed a positive correlation to the expression of the ribosomal protein p70S6K (r: 0.39, P = 0.02 9), which is involved in pro- tein synthesis. This correlation was not seen in donor tissue, whic h showed a trend for a negative correlation (r: 0.49, P = 0.08 ). Conclusion Our data indicate that the Ezh2/Six1 axis might be involved in human DCM. However, Six1 expression may be regulated by factors other t han Ezh2, and more research is needed to determine the precise role of Ezh2/Six1 in human DCM
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