1,721,047 research outputs found
The Monumental Temple Terrace at Urkesh and its Setting
Full text linkBuccellati, F. 2010. “The Monumental Temple Terrace at Urkesh and its Setting.” In Kulturlandschaft Syrien: Zentrum und Peripherie Festschrift für Jan-Waalke Meyer, edited by J. Becker, R. Hempelmann, and E. Rehm, 71–86. AOAT 371. Münster: Ugarit
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Magnetic nanoparticles for protein-protein interaction studies
No full textThe analysis of protein complexes and of protein interaction networks is a significant endeavor as nearly all biological processes involve regulated cooperation between multiple protein species in both time and space. Magnetic nanoparticles (NPs) may be used for studies in this field, resorting to a two-step process that involves the tagging or labeling of the desired biological entity with the particle, and the following separation of these tagged entities via mild fluid-based magnetic separation. This work aims at demonstrating the potential of magnetic NPs coated with specific “bait” proteins for addressing a number of reversible molecular interactions, such as protein-protein, antigen-antibody, and enzyme reactions.
Nano-sized probes were prepared by conjugating analytical-grade trypsin to conveniently activated magnetic NPs, and used to capture Kunitz-type trypsin inhibitor (KSTI) from a pure protein solution. After isolation of the interacting bait/prey couples (linked to the NPs), the resulting complexes were dissociated and the prey protein was identified by mass spectrometry, giving evidence of the peculiar binding between trypsin and its specific interactor.
Anti-gliadin immunoglobulins were also conjugated to NPs and used to recover gliadins according to the same approach. Immunoprecipitation experiments, followed by SDS-PAGE analysis revealed that gliadins specifically interacted with their antibodies.
These data indicate that our conjugation procedure does not impair the structure of proteins and the interactions with their appropriate biological systems. Moreover, pending investigation on more complex systems where the specific protein may eventually be present in traces, this exploratory study paves the way to use of these conjugates as nano-sized probes to separate biological entities from their native environment for their identification, quantitation, and further characterization
Conjugates between food proteins and magnetic nanoparticles : production and properties.
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