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Measure of body composition by MOC DEXA, in children and teenagers with eating disorders
No full textIntroduction
Feeding has various characteristics and parameters including preferences of certain foods and eating habits, meal profile, regulation of the sense of hunger and satiety. In nutrition disorders (DCA) we find a constant alteration in the relationship between food and the individual with tendencies to hyper nutrition or as opposed to hypo nutrition. This can lead to the medium and long term compromising physical health and / or social psychic relationships. Therefore eating disorders are of primary importance in both the psychic and nutritional spheres and must be addressed in a multidisciplinary manner.
Aim
The aim of the study was to retrospectively examine a group of patients with DCA in order to analyze and characterize patients regarding their body composition, evaluated by MOC-DEXA, anthropometric parameters and hematochemical parameters
Materials and methods
The study included 28 patients (26 females and 2 males) of mean age of 13.6 years. These patients were characterized by the evaluation of clinical records and the collection of informed consent. The following parameters were analyzed for each patient:
date of birth, origin, age at diagnosis, anthropometric parameters (weight, height, BMI), amenorrhea, quantification of physical activity, dose of 25 (OH) vitamin D, moc total body, left femoral muscle moc, spine moc and therapeutic pathway.
Data was processed using excell programs and statistical analysis was performed using SPSS 15.0 for windows.
Results
The sample examined shows that the starting age in about 50% of cases is between 13 and 14 years.
The average height of patients was 156.1 cm, weight 43.8 kg and BMI of 17.8 kg / m2. Physical activity averaged 4.64 hours / week.
Dosage of 25 (OH) vitamin D was 25.4 ng / ml, while the therapeutic route consisted in the integration of dietary-nutritional, psychotherapeutic and pharmacological treatments.
MOC showed the following mean results: BMC (Bone Mineral Content): 1560.5 g (s.d. ± 340.4) Total mass: 41280.2 g (s.d. ± 10946.8) Lean Mass: 31073.5 g (s.d. ± 5465.8)
Fat Mass: 10056.2 g (s.d. = 4157.8) Fat mass%: 23.5 (s.d. ± 7.6).
A comparison was also made between the group of patients with amenorrhea (n ° 18) and the menstrual patient group (n ° 8). The statistical analysis provided the following results:
• Amenorrhea and weight: Amenorrhea patients had lower weight (p = 0.021)
In our study we found a cut-off of weight corresponding to 43 Kg below which patients had amenorrhea
• Amenorrhea and BMI: Amenorrhea patients have lower BMI values: 16.6 versus 19.6 (p = 0.034)
• Amenorrhea and fat mass: Amenorrhea patients had lower fat mass: 8.2 g versus 13.9 g (p = 0.008)
• Amenorrhea and fat%: patients with amenorrhea showed fat less than menstruating patients:
20.6% versus 30.8% (p = 0.004)
• Amenorrhea and total mass: patients with amenorrhea had lower total mass than menstruating patients: 37078.9 g versus 46826.2 (p = 0.023)
Discussion and Conclusions
The results of our study show that the severity of the disease correlates well with early onset: earlier is the age of onset , more severe is the impairment in weight and body composition resulting in a reduction in lean mass and of bone mineral density but not in Fat mass amount. Our study shows that there are no menstruating patients with a weight below 43 kg, regardless of age and height. The weight t of 43 kg seems to be a true indicator to discriminate if there is or not amenorrhea. Amenorrhea remains an unfavorable prognostic factor that correlates with the severity of the disease, in fact, patients with amenorrhea have impaired body composition worse than patients with menstruation, with reduced bone mineral density of total mass and lean mass.
A further study with more patients is therefore necessary to confirm the data which, however, already well correlates with the clinical status of the patients
Sutton's nevus and growth hormone therapy.
No full textGrowth hormone (GH) has been suggested to increase the growth of melanocytic nevi and the risk for melanoma in short children treated with substitutive therapy. On the contrary, in GH deficient patients the influence of GH treatment on the appearance and the long-term evolution of Sutton's nevus, a pigmented melanocytic lesion surrounded by a ring (halo) of depigmentation, that usually and progressively involves the nevus, is debated. The aim of this study was to investigate whether GH therapy causes an accelerated growth of Sutton's nevus. In our study, we evaluated 3 children with GH deficiency sharing Sutton's nevus to investigate the relationship between these melanocytic lesions and growth hormone. In case 1 the appearance of the nevus could be induced by hGH therapy. However, the lesion did not change in shape, colour and size even if he entered puberty during substitutive treatment. Moreover, Sutton's nevus is present in case 2, who is prepuberal and not yet treated with hGH. In case 3 Sutton's nevi occurred during GH treatment and after the onset of puberty, but didn't show any long-term change in both the number and size. No clear influence of both GH therapy and sexual steroids on Sutton's nevi was observed
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Resting energy expenditure in patients affected by glicogen storage disease type I and III
No full textThree patients with the severe form of propionic acidaemia were treated with living-donor liver transplantation (LDLT). The procedure was successful for all patients and the incidence of metabolic decompensation was reduced dramatically even without protein restriction. Biochemically, however, the improvement was not significant and the patients continued to excrete large amounts of propionic acid metabolites. One of the patients experienced a severe acidaemic episode 3 years after transplantation. LDLT has a beneficial effect on the care of severely affected patients since it reduces the risk of metabolic decompensation and improves the quality of life with less strict dietary control. Adequate protein restriction and medication need to be maintained even after successful transplantation
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