607 research outputs found
Le chant du gondolier : barcarolle pour piano : op. 57 / par J. G. Daddi ; [orn. par] Æ
Titre uniforme : Daddi, J. G. (18..-19.. ; compositeur). Compositeur. [Le chant du gondolier. Piano. Op. 57]Piano, Musique de -- +* 1800......- 1899......+:19e siècle:Barcarolles (piano) -- +* 1800......- 1899......+:19e siècle
[Surgical treatment of well differentiated neuroendocrine tumours of the lung].
The bronchial tree represents the most frequent site of origin of carcinoids (around 25% of the total). The spectrum of differentiation of lung neuroendocrine tumors ranges from low-malignancy (carcinoids) to highly aggressive forms (small cell lung carcinoma) Diagnostic and therapeutic strategies therefore vary greatly. In well differentiated tumors (carcinoids) signs and symptoms are related to the airways obstruction in central forms, while peripheral forms are mostly discovered accidentally if asymptomatic. Clinical or subclinical paraneoplastic syndromes are associated in a minority of cases. Diagnostic work-up includes CT multislice, bronchial endoscopy and Octreoscan with chest Single Photon Emission Computed Tomography (SPECT). Further contribute may be added by the (68), Ga-DOTA-D-Phe(1)-Tyr(3)-ocreotide (DOTATOC) and 5-hydroxytryptophan (5-HTP) PET-CT, at present available only in a few centres, and by endobronchial ultrasound (EBUS), fluorescence bronchoscopy and virtual bronchoscopy. Surgery is the treatment of choice, while medical therapy is useful to treat the hypersecretion in paraneoplastic syndromes and to control tumor proliferation in metastatic or/and inoperable disease
Uterine Leiomyoma Metastatic to the Lung
Introduction: Uterine leiomyomas belong to a heterogeneous family of tumors with peculiar biological behaviour. Pulmonary metastases may originate from frankly malignant leiomyomas (sarcomas) as well as from so called benign metastasizing leiomyomas. Latency between hysterectomy and metastatic disease may vary from few months to several years. We report two cases with an exceptionally long latent period.
Methods: Two cases of apparently primary giant lung tumor were observed. Both presenting clinical history of fever and malaise. Chest x-ray showed in both cases a left pulmonary opacity. Preoperative work-up yielded the diagnosis respectively of epithelial and mesenchymal tumor without extrapulmonary localization (CT and PET-CT).
Results: Case N 1: 68 year-old (Z.A.), the giant lobulated tumor, invading the hilar structures, required a left pneumonectomy. Histology revealed a metastatic uterine leiomyoma. She had under- gone hysterectomy for multiple leiomyomas 21 years previously. Case N 2: 66 year-old (M.M), was submitted to left pneumonectomy for a giant tumor extended to both lobes. Also in this case metastasis from uterine leiomyoma was diagnosed and confirmed by comparison with histology from hysterectomy (performed 16 years previously). There was no peri-operative mortality. Both the patients are alive without evidence of disease 6 and 3 months after surgery.
Discussion: These cases suggest that the diagnosis of primary pulmonary sarcoma needs careful pathological assessment and follow-up of the patients submitted to hysterectomy for leiomyoma should be protracted
Long-term safety and tolerance of silicone and self-expandable airway stents: an experimental study.
Long-term safety and tolerance of silicone and self-expandable airway stents: an experimental study
BACKGROUND:
A variety of respiratory stents are currently available, but the ideal airway prosthesis seems far from being recognized. The objective of this study was to verify safety and long-term effect on the bronchial wall of three different types of airway stents.
METHODS:
Twelve healthy adult sheep were divided in three groups, scheduled to receive: (1) bare self-expandable metallic stents (Gianturco); (2) silicone stents (Dumon); and (3) covered self-expandable synthetic stents (Polyflex). Insertions were performed through a rigid bronchoscope under general anesthesia. Chest roentgenogram was performed 1 and 6 months after surgery, and flexible bronchoscopy after 6 months. Twelve months postoperatively, the animals were killed and a postmortem examination was carried out.
RESULTS:
All Polyflex stents migrated during the observation period; one late migration was observed in the Dumon group. Microscopic study showed: (1) Gianturco stents: full-thickness perforation of the bronchial wall covered by a thick layer of a chronic inflammatory infiltrate. Infection by Candida at the bottom of some ulcerations; (2) Dumon stents: mild bronchial inflammation (squamous metaplasia, submucosal inflammatory infiltrates; granuloma-like infiltrates). In case of displacement, no significant changes of the previously stented bronchus occurred; and (3) Polyflex stents: no changes of the previously stented bronchi.
CONCLUSIONS:
Gianturco stents proved unsafe in the long term, owing to the risk of severe airway wall damage. The Polyflex stent is well tolerated but presents a high migration rate. Silicone stents show several limitations but appear to be well tolerated by the host mucosa
Narrare gli eventi bellici:cronaca e storia di alcuni conflitti eccellenti nella rappresentazione visiva della Mesopotamia e della Siria perclassiche
Surgical Treatment of Non Malignant Tracheal Lesions: A Single Center Experience
Introduction: Different etiologies are responsible for a wide spectrum of tracheal injuries. Some of these, such as cicatricial laryngo-tracheal stenosis and tracheoesophageal fistula (T-E) not rarely represent a challenge in tracheal surgery. Aim of this study is to retrospectively review the pattern of post-intubation lesions, extension of surgery and long term results in 49 patients.
Methods: From December 1987 to February 2007, 49 patients (23 males and 26 females), mean age 50 (range 15–78), were submit- ted to surgical treatment: cicatricial tracheal stenosis (Group A), T-E fistula (Group B), and tracheal tear (Group C). All patients were symptomatic.
Results: No post-operative deaths. In Group A (n = 34) the stricture was considered moderate (residual lumen:30–50%) in 27 patients, and severe (<30%) in 7. Tracheal resection and reconstruc- tion (RR) was performed in 24 cases, laryngo-tracheal RR in 10. Two major complications were observed (partial dehiscence of the suture). In group B (n = 10): all patients underwent tracheal RR and direct closure of the T-E fistula. One patient died 10 days postop; 1 with minimal recurrence of the T-E fistula was treated by a temporary T- tube. In group C (n = 5): 3 patients (tear of the membranous wall) were submitted to immediate tracheal suture (right thoracotomy) protected with an intercostal-muscle flap. A trans-tracheal approach trough cervico-sternotomy was adopted in one case. One patient (small sub-cricoid tear) was treated in a conservative way.
Discussion: Good surgical results in the treatment of non- neoplastic tracheal lesions are based on: (1) patient selection; (2) tim- ing of surgery; (3) preoperative therapy; (4) meticulous surgical technique
The spatial clustering of X-ray selected AGN and galaxies in the Chandra Deep Field South and North
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