1,720,994 research outputs found
Interactions between N–acetylcysteine and sodium selenite in modulating the clastogenicity of urethane and 2–acetylaminofluorene in mice
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Modulation of light–induced skin tumors by N–acetylcysteine and/or ascorbic acid in hairless mice
No full text[Research on adducts of benzo(a)pyrene and DNA in different cells using synchronous fluorescence spectrophotometry].
No full textThe levels of benzo(a)pyrene diolepoxide(BPDE)-DNA adducts were measured in rat and human cells by synchronous fluorescence spectrophotometry. BPDE-DNA adducts detected in human pulmonary alveolar macrophages were related to current smoking habits, in contrast to the adducts found in peripheral blood leukocytes. BP administration to rats produced BPDE-DNA adducts in both liver and lungs. Although small yet repeatable signals were also detected in lung DNA from rats treated for 3 days with tobacco smoke. None of the samples obtained from untreated animals was positive. The detection of BPDE-DNA adducts may be used in biomonitoring and experimental studies for determining of exposure to BP even when applied as a constituent of complex mixtures
Applicazione di tecniche di biologia molecolare all'epidemiologia e prevenzione delle malattie cronico-degenerative ed all'igiene ambientale
No full textPrevention of cigarette smoke-induced lung tumors in mice by budesonide, phenethyl isothiocyanate, and N-acetylcysteine.
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dose-related cytogenetic damage in pulmonary alveolar macrophages from mice exposed to cigarette smoke early in life.
No full textBirth-related genomic and transcripional changes in mouse lung. Modulation by transplacental N-acetylcysteine.
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