1,206 research outputs found
D02. NCNPR Activities at Coy Waller Complex
No full textCorresponding author (NCNPR, School of Pharmacy): Mohamed M. Radwan, [email protected]://egrove.olemiss.edu/pharm_annual_posters/1024/thumbnail.jp
Draft legislation guidelines for the establishment of a specialized Capital Market Court in Poland
No full textNa zlecenie Giełdy Papierów Wartościowych S.A. w Warszawie Instytut Zaawansowanych Studiów Prawnych im. Profesora Maurycego Allerhanda z siedzibą w Krakowie, powszechnie znany jako Instytut Allerhanda, opracował w 2018 r. koncepcję wydzielenia w polskim wymiarze sprawiedliwości specjalistycznego sądu dla spółek publicznych.
Założenia do tzw. „ustawy o Sądzie Rynku Kapitałowego” przygotował adw. dr. hab. Arkadiusza Radwan, we współpracy z r. pr. Michałem Bobrzyńskim, LLM (Harvard), r. pr. Kamilem Nowakiem oraz dr. Krzysztofem Grabowskim – współpracownikami naukowymi Instytutu Allerhanda.
Prezentujemy dokument w oryginalnej formie przekazanej Zarządowi GPW 5 grudnia 2018 r.In 2018 the Warsaw Stock Exchange commissioned the Allerhand Institute, to draw up assumptions for a legislation introducing into the Polish judicial system a separate specialized Capital Market Court competent in corporate law disputes of listed companies as well as disputes between investors and issuers of financial instruments. Moreover the jurisdiction of new court would extend to embrace judicial review of decisions issued by the Polish Financial Supervision Authority (KNF). The document was prepared by Professor Arkadiusz Radwan, in cooperation with Michał Bobrzyński (Attorney-at-Law, LL.M. Harvard), legal advisor Kamil Nowak (Attorney-at-Law) and Dr. Krzysztof Grabowski – all research associates affiliated with the Allerhand Institute. This is to present an original document submitted to the Board of the Warsaw Stock Exchange on 5 December 2018
Założenia do ustawy o Sądzie Rynku Kapitałowego
No full textNa zlecenie Giełdy Papierów Wartościowych S.A. w Warszawie Instytut Zaawansowanych Studiów Prawnych im. Profesora Maurycego Allerhanda z siedzibą w Krakowie, powszechnie znany jako Instytut Allerhanda, opracował w 2018 r. koncepcję wydzielenia w polskim wymiarze sprawiedliwości specjalistycznego sądu dla spółek publicznych.
Założenia do tzw. „ustawy o Sądzie Rynku Kapitałowego” przygotował adw. dr. hab. Arkadiusza Radwan, we współpracy z r. pr. Michałem Bobrzyńskim, LLM (Harvard), r. pr. Kamilem Nowakiem oraz dr. Krzysztofem Grabowskim – współpracownikami naukowymi Instytutu Allerhanda.
Prezentujemy dokument w oryginalnej formie przekazanej Zarządowi GPW 5 grudnia 2018 r.Teisės fakultetas / Faculty of LawVytauto Didžiojo universitetas / Vytautas Magnus Universit
Poetry ars divina: Musaeus’ Prophetic Oration in the Epic Poem Radivilias by Jan Radwan
No full textHeroic epic poem entitled Radivilias sive de vita et moribus praeclarissime gestis immortalis memoriae illustrissimi principis Nicolai Radivili … libri quattuor, by Jan Radwan, was published in Vilnius in 1592.
The historical narration about the chief events connected with the Livonian War (1558-1582) when Poland and the Great Duchy of Lithuania were struggling against Ivan, the Terrible serves as a setting for a panegyric portrait of the main hero of the poem, Mikołaj Radziwiłł, the Red and his heroic deeds.
The author of Radivilias takes Radziwiłł to Helicon, place sacred to a succession of poetic memories, where he meets Musaeus. This part of the poem resembles Cicero’s Dream of Scipio, but we can see an essential difference between these two texts (Cicero - dream, dead ancestors, rational justification, Radwan - mythological motif, legendary poet Musaeus and poetry as a source of wisdom). Radwan is very realistic. He does not dream about return of the Golden Age, but emphasises the fragility of earthly glory and concentrates his attention upon the only true life - the life after death.
This article aims at discussing Radwan’s conception of the function of the Musaeus’ prophecy in the whole context of the poem. The attention is being given also to a prohetic significance of poetry
Alternative Lime Based Grouts Used in Re-pointing of Deteriorated Ancient Mortars and their Structural Effects on Composite Unreinforced Masonry Walls of Mekaad Radwan, Ottoman Cairo, Egypt (Case Study)
No full textAbstractMortars and plasters of Mekaad Radwan are badly affected by decay hazards, therefore; they were studied by means of XRD and polarized microscope to detect their chemical composition, physical and petrographic properties, in addition to identify their characteristics. The analyses revealed gypsum mixed with lime as dominant component with some aggregates of sand particles, sodium chloride was detected in all the studied samples. Standardized alternative mortars were prepared, exposed to artificial aging and tested in order to select the most suitable type to replace the old mortars and plasters at Mekaad Radwan
Intracranial haemorrhage associated with cerebral infections: A review
No full textWe present a review of the different viral, bacterial, parasitic and fungal infections that are associated with intracranial haemorrhages. We summarize the clinical presentation of the infection and its cerebral complication. We elucidate the pathology and pathophysiology of the haemorrhage as being spontaneous or secondary to vasculitis, thrombosis, embolization or aneurysmal formation. © 2011 Informa Healthcare.AKE JA, 2006, CLIN INFECT DIS, V43, P46; ARGYRIOU A, 2006, SCAND J INFECT DIS, V1, P63; Boudewijns M, 2003, CLIN MICROBIOL INFEC, V9, P222, DOI 10.1046-j.1469-0691.2003.00503.x; BURKE JM, 1985, NEUROLOGY, V35, P1368; Chan KH, 2005, CEREBROVASC DIS, V19, P391, DOI 10.1159-000085568; Chehrenama M, 1997, NEUROLOGY, V48, P520; Chukwudelunzu FE, 2002, EUR J NEUROL, V9, P423, DOI 10.1046-j.1468-1331.2002.00432.x; Cole JW, 2004, STROKE, V35, P51, DOI 10.1161-01.STR.0000105393.57853.11; Connor MD, 2000, STROKE, V31, P2117; DASTUR DK, 1995, RADIOL CLIN N AM, V33, P733; Dubrovsky T, 1998, NEUROLOGY, V51, P560; ELKIND M, 2010, ARCH NEUROL-CHICAGO, V67, pE1; Endo T, 2002, NEUROSURGERY, V50, P1147, DOI 10.1097-00006123-200205000-00039; Erly WK, 1999, AM J NEURORADIOL, V20, P1605; Flint AC, 2005, NEUROLOGY, V64, P391; Gall C, 1999, NEW ENGL J MED, V341, P611, DOI 10.1056-NEJM199908193410814; Gautschi O, 2003, RESPIRATION, V70, P419, DOI 10.1159-000072908; Gkrania-Klotsas Effrossyni, 2008, J Med Case Rep, V2, P387, DOI 10.1186-1752-1947-2-387; Grau AJ, 2005, STROKE, V36, P1501, DOI 10.1161-01.STR.0000170674.45136.80; Heiro M, 2000, ARCH INTERN MED, V160, P2781, DOI 10.1001-archinte.160.18.2781; Hofer M, 2005, ACTA NEUROPATHOL, V109, P226, DOI 10.1007-s00401-004-0930-3; Jacobi C, 2006, EUR J NEUROL, V13, P536, DOI 10.1111-j.1468-1331.2006.01335.x; Jain R, 2003, AM J NEURORADIOL, V24, P971; Kannoth S, 2009, NEUROCRIT CARE, V11, P120, DOI 10.1007-s12028-009-9208-x; KAYA S, 2008, NEUROSURG REV, V1, P337; KIKUTA H, 1993, BLOOD, V82, P3259; KURE K, 1989, Pediatric Pathology, V9, P655; Lim KK, 2009, J CLIN NEUROSCI, V16, P140, DOI 10.1016-j.jocn.2008.02.017; Maniker AH, 1996, SURG NEUROL, V46, P49, DOI 10.1016-0090-3019(96)00030-4; MCGUIRE D, 1999, AIDS KNOWLEDGE BASE, P445; Miyamoto S, 2006, NEUROL MED-CHIR, V46, P348, DOI 10.2176-nmc.46.348; Mochan A, 2003, STROKE, V34, P10, DOI 10.1161-01.STR.0000043821.35051.FA; Modi G, 2008, J NEUROL NEUROSUR PS, V79, P44, DOI 10.1136-jnnp.2006.108878; MUHPATRA AK, 1988, J ASSOC PHYSICIAN I, V36, P237; MURUGAVEL K, 1989, POSTGRAD MED J, V65, P236; Nigro G, 2002, PRENATAL DIAG, V22, P558, DOI 10.1002-pd.366; Ortiz JU, 2004, ULTRASOUND OBST GYN, V23, P402, DOI 10.1002-uog.1021; Pinto AN, 1996, STROKE, V27, P538; Piovesan EJ, 1997, ARQ NEURO-PSIQUIAT, V55, P126; Rich AR, 1933, B JOHNS HOPKINS HOSP, V52, P5; Scheid R, 2003, EUR J NEUROL, V10, P99, DOI 10.1046-j.1468-1331.2003.00541.x; SCULLY RE, 1996, NEW ENGL J MED, V335, P1587; SNIDER WD, 1983, ANN NEUROL, V14, P403, DOI 10.1002-ana.410140404; Sundaram C, 2007, J CLIN NEUROSCI, V14, P882, DOI 10.1016-j.jocn.2006.05.014; Takeda H, 2002, NEUROL MED-CHIR, V42, P361, DOI 10.2176-nmc.42.361; Uesugi T, 2006, INTERNAL MED, V45, P1193, DOI 10.2169-internalmedicine.45.6116; Vejjajiva A, 1978, Clin Exp Neurol, V15, P92; WIJDICKS EFM, 1991, ANN NEUROL, V29, P683, DOI 10.1002-ana.410290620; Yanagihara C, 2003, INTERNAL MED, V42, P1244, DOI 10.2169-internalmedicine.42.1244; Yeh STY, 2003, J EMERG MED, V25, P265, DOI 10.1016-S0736-4679(03)00200-2; Yoneda H, 2005, CEREBROVASC DIS, V19, P209, DOI 10.1159-00008388422
Geognostic Investigation on Damage and Deterioration Evolution of Soil and Architectural Materials of Mekaad Radwan, Ottoman Cairo, Egypt (Case Study)
No full textAbstractThis study determines which factors play roles of deterioration in Mekaad Radwan. The study also makes it possible to know the real response of the masonry structure to the deformation imposed at the base of the foundation condition. The used methodology included the identification of the seismicity situation and the possible damage effects of the Cairo (1992) earthquake through discussion of situation before and after earthquake as well as the controlling factors, in addition to the analysis and determination of the types, geometry of the types, deformation and other deterioration patterns, using the direct observation and primitive monitoring evaluation
Marian Radwan, Ecclesiastica w Rosyjskim Państwowym Archiwum Historycznym w Sankt Petersburgu : recenzija
No full textRecenzuojama knyga skirta ne plačiajai skaitytojų auditorijai, bet neabejotinai verta Lietuvos istorikų, tyrinėjančių Lietuvos Bažnyčios istorijos bei XIX–XX a. religinio gyvenimo peripetijas, dėmesio. Rusijos valstybiniame istorijos archyve (RVIA) Sankt Peterburge didelį darbą atlikusio lenkų profesoriaus Mariano Radwano veiklą vainikuoja naujas žinynas, kuriame pristatomi RVIA esantys vadinamieji bažnytiniai fondai. Žinyne apsiribojama katalikų ir unitų Bažnyčių istoriją atskleidžiančiais archyviniais šaltiniais. Įvadiniame straipsnyje autorius trumpai aptaria katalikų ir unitų istorijai svarbius RVIA fondus, pateikia apie juos glaustus duomenis ir pagrindinius skaičius, pristato žinyno sudarymo principus. Dėmesį sutelkęs ties dviem Bažnyčiomis – katalikų ir unitų, autorius žinyne pagrįstai išskiria du stambius skyrius: Romos katalikų Bažnyčios archyvai ir Graikų katalikų Bažnyčios archyvai, kiekviename jų pateikdamas atskirus teminius blokus pagal fondus. Daugiausia teminių blokų autorius išskyrė Kitatikių dvasinių reikalų departamento fonde. Pavadinimai įvardija dokumentų turinį, o išdėstymas pagal abėcėlę palengvina paiešką. Tarp baigiamųjų įvadinio straipsnio eilučių galima įskaityti, kad RVIA vadovybės palaikymo žinyno autorius neturėjo. Turint tai omenyje, žinynas įgauna dar ir kitą vertę, tapdamas vaizdžiu dabartinės katalikų Bažnyčios situacijos sparčiai sekuliarėjančiam pasauly istorijos faktu. Reikšminiai žodžiai: Ekleziastika; Ekleziologija; Katalikų ir unitų Bažnyčios dokumentai; M. Radwan; RVIA; Sankt Peterburgo valstybinis istorinis archyvas; Documents Catholic and Uniate Churches; Ecclesiastica; Ecclesiology; M. Radwan; Russian state archive; State Historical Archives of St. PetersburgThe reviewed book is not targeted at a wide audience, but is definitely worth the attention of Lithuanian historians who investigate the peripaetia of the history of the Lithuanian Church and the religious life in the 19th–20th c. The activities of Polish Professor Marian Radwan, who did a huge work in the Russian State Historical Archive (RSHA) in Saint Petersburg, have been crowned by a new directory which presents the church stocks kept at the RSHA. The directory is limited to the archival sources revealing the history of the Catholic and Uniate Churches. The introductory article briefly discusses the RSHA stocks relevant to the history of Catholics and Uniates, gives concise data and key figures and presents the principles of the structure of the directory. Focusing on two Churches – Catholic and Uniate – the author reasonably distinguishes two large chapters: the archives of the Roman Catholic Church and the archives of the Greek Catholic Church. Each chapter contains thematic units according to the stocks. The stocks of the Department for Spiritual Affairs of Foreign Confessions have the biggest number of thematic units. The titles name the content of documents and the alphabetical order facilitates the search. The final lines of the introductory article inform that the author of the directory received no support from the RSHA management. With this in mind, the directory acquires additional value by becoming an ostensive historical fact of the current Catholic Church situation in the rapidly secularising world
Bounds for increasing multi-state linear <i>k</i>-within-(<i>r</i>,<i>s</i>)-of-(<i>m</i>,<i>n</i>):<i>F</i> lattice system
No full text
Purpose
A multi-state linear k-within-(r, s)-of-(m, n): F lattice system consists of m×n components arranged in m rows and n columns. The possible states of the system and its components are: 0, 1, 2, …, H. According to k values, the system can be categorized into three special cases: decreasing, increasing and constant. The system reliability of decreasing and constant cases exists. The purpose of this paper is to evaluate the system reliability in increasing case with i.i.d components, where there is no any algorithm for evaluating the system reliability in this case.
Design/methodology/approach
The Boole-Bonferroni bounds were applied for evaluating the reliability of many systems. In this paper, the author reformulated the second-order Boole-Bonferroni bounds to be suitable for the evaluation of the multi-state system reliability. And the author applied these bounds for deriving the lower bound and upper bound of increasing multi-state linear k-within-(r, s)-of-(m, n): F lattice system.
Findings
An illustrated example of the proposed bounds and many numerical examples are given. The author tested these examples and concluded the cases that make the new bounds are sharper.
Practical implications
In this paper, the author considered an important and complex system, the multi-state linear k-within-(r, s)-of-(m, n): F lattice system; it is a model for many applications, for example, telecommunication, radar detection, oil pipeline, mobile communications, inspection procedures and series of microwave towers systems.
Originality/value
This paper suggests a method for the computation of the bounds of increasing multi-state linear k-within-(r,s)-of-(m,n): F lattice system. Furthermore, the author concluded that the cases that make these bounds are sharper.
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Hyaluronic-Coated Albumin Nanoparticles for the Non-Invasive Delivery of Apatinib in Diabetic Retinopathy
No full textSalma El-Sayed Radwan,1 Amal El-Kamel,1 Eiman I Zaki,2 Susi Burgalassi,3 Erica Zucchetti,3 Riham M El-Moslemany1 1Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt; 2Department of Histology and Cell Biology, Faculty of Medicine, Alexandria University, Alexandria, Egypt; 3Department of Pharmacy, University of Pisa, Pisa, ItalyCorrespondence: Riham M El-Moslemany 1, Khartoum Square, Azarita, Alexandria, EgyptTel +11 201006020405Email [email protected]: Apatinib (Apa) is a novel anti-vascular endothelial growth factor with the potential to treat diabetic retinopathy (DR); a serious condition leading to visual impairment and blindness. DR treatment relies on invasive techniques associated with various complications. Investigating topical routes for Apa delivery to the posterior eye segment is thus promising but also challenging due to ocular barriers. Hence, the study objective was to develop Apa-loaded bovine serum albumin nanoparticles (Apa-BSA-NPs) coated with hyaluronic acid (HA); a natural polymer possessing unique mucoadhesive and viscoelastic features with the capacity to actively target CD44 positive retinal cells, for topical administration in DR.Methods: Apa-BSA-NPs were prepared by desolvation using glutaraldehyde for cross-linking. HA-coated BSA-NPs were also prepared and HA: NPs ratio optimized. Nanoparticles were characterized for colloidal properties, entrapment efficiency (EE%), in vitro drug release and mucoadhesive potential. In vitro cytotoxicity on rabbit corneal epithelial cells (RCE) was assessed using MTT assay, while efficacy was evaluated in vivo in a diabetic rat model by histopathological examination of the retina by light and transmission electron microscopy. Retinal accumulation of fluorescently labeled BSA-NP and HA-BSA-NP was assessed using confocal microscope scanning.Results: Apa-HA-BSA-NPs prepared under optimal conditions showed size, PdI and zeta potential: 222.2± 3.56 nm, 0.221± 0.02 and − 37.3± 1.8 mV, respectively. High EE% (69± 1%), biphasic sustained release profile with an initial burst effect and mucoadhesion was attained. No evidence of cytotoxicity was observed on RCE cells. In vivo histopathological studies on DR rat model revealed alleviated retinal micro- and ultrastructural changes in the topical HA-Apa-BSA-NP treated eyes with normal basement membrane and retinal thickness comparable to normal control and intravitreally injected nanoparticles. Improved retinal accumulation for HA-BSA-NP was also observed by confocal microscopy.Conclusion: Findings present HA-Apa-BSA-NPs as a platform for enhanced topical therapy of DR overcoming the devastating ocular complications of the intravitreal route.Keywords: retinopathy, apatinib, bovine serum albumin, hyaluronic, mucopenetration, active targetin
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