1,720,967 research outputs found
Case for diagnosis: 4-month-old infant with increasing cough, hemoptysis, and anemia
No full textAbstract: A 4-month-old caucasian infant presented non-productive cough, fever associated with hemoptysis, and increasing anemia. He had mild tachypnoea; routine lab tests were normal. The thoracic HRCT scan showed a very large mass in the right lung adherent to the thorax wall, well defined and limiting the medium and upper lobe; the mass was well vascularized, and with central hypodensic areas. Fiberoptic bronchoscopy and bronchoalveolar lavage (BAL) cytology were normal. The definitive histology of the mass showed the presence of inflammatory cells admixed with fibroblasts and rare Touton giant cells in the lesion suggestive of a juvenile xanthogranulorna (JXG)of the lung
Further experience with OK-432 for lymphangiomas
No full textAbstract: This study includes all the children treated with OK-432 for lymphangioma at our institute. Twenty-nine children treated between 1999 and 2003 are reported for the first time: twelve cases regressed completely, eight cases regressed more than 50% and seven remained unchanged; two cases were lost at follow-up. The outcome was related to the size of the cysts, the larger ones having a better prognosis. The adverse reactions are discussed and the methods of treatment are described in detail. Fifteen children, treated before 1999 and already reported, are reviewed after a long-term follow-up. Four had a recurrence: one regressed spontaneously and three needed further treatment. The other 11 had no complaints. Even considering the risk of recurrence, OK-432 therapy remains our first line therapy for lymphangiomas, avoiding surgery in most cases
Central venous access in pediatric patients
No full textOcclusion of traditional sites for central venous cannulation is a challenging problem in patients that require a permanent central venous line for chronic administration of nutrients or drugs. In rare cases, extensive central venous thrombosis of the superior and inferior vena cava may preclude catheterization, and uncommon routes should be used. We describe our approach for placement of chronic central venous lines in two pediatric patients with short bowel syndrome and extensive caval occlusio
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Two-dimensional atrial systolic strain imaging predicts the onset of atrial fibrillation at 4-year follow-up in patients with asymptomatic mitral stenosis
No full textSurgical management of adnexal torsion in children and adolescents: update and review of the literature.
Full text linkThis article aims to systematically illustrate the most relevant approach to follow in cases of suspected adnexal torsion in adolescents. We based our evaluation of the role of clinical features, laboratory tests and imaging on recent literature (2013-2015), till we consider the most appropriate surgical treatment which has been reached during our experience. Particularly, this study proves– through the literature review and the evaluation of a record of cases- that conservative treatment is to date the most highly recommended surgical approach for AT. To assess the state of ovarian tissue and proceed with the most adequate surgical approach, an intraoperative frozen section analysis may be helpful in selected cases. Recent experimental studies have focused on the consequences of detorsion, which may cause ischemia-reperfusion damage and have speculated about the role of different drugs for its avoidance
Multidisciplinary Surgical Approach to a Surviving Infant With Sirenomelia
No full textSirenomelia is an extremely complex and rare malformation with different degrees of lower-extremities fusion
associated with gastrointestinal, musculoskeletal, vascular, cardiopulmonary, and central nervous system malformations.
In the English literature, there are only 5 reports of infants surviving with this condition. In our case, a 2540-g
female infant was born with normal vital signs, no facial dysmorphism, and a complete soft tissue fusion of the lower
limbs, from perineum to ankles. Radiologic examinations revealed an intestinal atresia and a single pelvic kidney,
with a unique ureter, 2 femurs, 2 tibias, 2 fibulas, and 2 feet (simpus dipus). At 7 months of age, a multidisciplinary
surgical team achieved complete separation of the lower limbs, with independent vascular and nerve supplies. At the
time of this writing, the infant was 28 months old and had a regular growth curve. Many future reconstructive
surgeries have been planned to achieve an acceptable quality of life for this infant
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