1,721,115 research outputs found
Application of a stochastic model to intermodal units operations in rail – maritime terminals
No full textThe authors are developing an original model based on the queuing theory allowing the calculation of the transit time through railway freight terminals (TTR). The paper focuses on sea – rail interchanges in ports and describes the model customisation to ports applications and the results obtained in some case studies. Particular aspects described in this paper are linked to the quantification of the effects of relevant parameters affecting the quality of the model results: 1. different typologies and sizes of intermodal units; 2. additional unit movements due to co-existence of empty and full unit flows
La quantificazione dei parametri operativi chiave nei terminali intermodali merci: prestazioni ed applicazioni di un metodo
No full textGli argomenti esposti nel presente articolo fanno parte di una ricerca sullo sviluppo di un modello analitico basato su applicazioni della teoria delle code in grado di calcolare il valore del tempo di transito (TTR) della singola unità di carico (ITU) all’interno dei terminali intermodali merci in modo sintetico, ma nel contempo generalizzabile ad un ampia gamma tipologica di terminali. Il TTR è considerato un importante parametro di valutazione delle prestazioni operative e una componente fondamentale
del costo generalizzato del trasporto merci; per questo motivo l’analisi quantitativa di tale parametro risulta essere un’attività strategica per la pianificazione operativa del terminale sia in fase di progettazione che di esercizio. L’articolo mostra l’applicazione del modello e i risultati ottenuti per due casi studio (interscambio
mare-ferrovia nei terminali marittimi Terminal Darsena Toscana – Porto di Livorno e TIV – Porto di Venezia)
Un modello probabilistico per la quantificazione delle prestazioni e l’ottimizzazione operativa dei terminali intermodali merci.
No full textI terminali merci intermodali svolgono un ruolo fondamentale all’interno della catena logistica plurimodale.
Il tempo di transito (TTR) della singola unità di carico (UC) all’interno di questi terminali rappresenta uno dei più importanti parametri di valutazione prestazionale e, allo stesso tempo, una componente fondamentale del costo generalizzato del trasporto merci; per questo motivo l’analisi quantitativa di tale parametro risulta essere una attività strategica sia per la pianificazione operativa del terminale, sia per l’organizzazione della stessa catena logistica.
La presente ricerca si occupa dello studio di un modello basato su applicazioni della teoria delle code in grado di calcolare il valore del TTR in modo sintetico, ma nel contempo generalizzabile ad un ampia gamma tipologica di terminali
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mechanical noxious stimuli cause bilateral activation of parietal operculum in callosotomized subjects.
No full textThe patterns of cortical activation evoked by tactile and mechanical painful stimulation in six normal subjects and three patients with complete resection of the corpus callosum are described and compared, with emphasis on the parietal operculum. Stimulus-related cortical activation was investigated by functional magnetic resonance imaging. In both groups, painful stimulation activated the first somatosensory, insular and cingulate cortices in the contralateral hemisphere, and the parietal opercular cortex in both hemispheres. Comparison between the two patterns of cortical activation demonstrated that ipsilateral activation by unilateral painful stimulation is at least partially independent of the corpus callosum and suggests a different organization of the pain and touch systems
From pathogenesis to personalized treatments of neuropathies in hematological malignancies
No full textThe peripheral nervous system may be involved at any stage in the course of several hematological diseases, the most common being monoclonal gammopathies (of undetermined significance or malignant) or lymphomas. The underlying pathogenic mechanisms are different and therapies aim at targeting the dangerous either B-cell or plasma cell clones. Recently, high-throughput technologies, and next-generation sequencing have increased our knowledge of hematological diseases pathogenesis by the identification of somatic mutation affecting pivotal signaling pathways. Accordingly, new target therapies are used that may also be borrowed for treatment of neuropathies in hematological diseases
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