1,404 research outputs found

    Peer Interview Script, Danielle Mitchell, Spring 2020

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    Danielle Mitchell is a rising senior from Compton, California majoring in anthropology and sociology. She is a gifted writer who conducted very special interviews in SIS Seminar

    In the Garden, Danielle Mitchell, Spring 2020

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    Danielle Mitchell is a rising senior from Compton, California majoring in anthropology and sociology. She is a gifted writer who conducted very special interviews in SIS Seminar

    Hall Street, Danielle Mitchell, Spring 2020

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    Danielle Mitchell is a rising senior from Compton, California majoring in anthropology and sociology. She is a gifted writer who conducted very special interviews in SIS Seminar

    Excerpts of Interviews with Peers, Danielle Mitchell, Spring 2020

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    Danielle Mitchell is a rising senior from Compton, California majoring in anthropology and sociology. She is a gifted writer who conducted very special interviews in SIS Seminar

    How to write a novel - four fiction writers on Danielle Steel's insane working day

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    First paragraph: She might be the world’s most famous romance writer, nay the highest selling living author bar none, but there’s little room for flowers and chocolates in Danielle Steel’s writing regime. In a recent interview she laughed at the idea of young people insisting on a work-life balance, and has claimed she regularly writes for 20 to 22 hours a day, and sometimes 24. The result: 179 books in under 50 years, selling about 800m copies.https://theconversation.com/how-to-write-a-novel-four-fiction-writers-on-danielle-steels-insane-working-day-11715

    Conversations with Danielle Cronin, Philip Howard and Julian Thomas

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    This chapter focuses on the expanding civic role and challenges for investigative journalists using digital and social media. The chapter includes conversations with Danielle Cronin (national deputy editor of the Australian Broadcasting Corporation), as well as Professor Philip Howard (director of the Oxford Internet Institute), along with Distinguished Professor Julian Thomas (director of the ARC Centre of Excellence at RMIT University). They share their insights into setting an agenda of priorities for research and practice about public interest journalism. This chapter is an edited transcription of their conversations with the author, Dr Caryn Coatney, for a panel session sponsored by the Australian and New Zealand Communication Association. - This chapter provides new material about the impact of social media, online audiences and automation on investigative journalism

    Adding Spice to the Slog: Humanities in Medical Training.

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    Writing from personal experience, physician and author Danielle Ofri asks what evidence is needed to justify trying to humanize medical training via the power of literature

    2009 Open Access Week: Copyright and Author Rights

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    A talk about copyright by Danielle M. Conway

    Grounded imaginaries: Transforming how we live in climate-changed futures

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    Danielle Celermajer (Sydney), author of Summertime and owner of the bushfire-surviving Jimmy the Pig, ponders futures made possible by transforming the stories we tell.Griffith ReviewNo Full Tex

    Role of LINC01614 in Papillary Thyroid Cancer

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    Papillary thyroid cancer (PTC) accounts for the majority of thyroid cancer cases (~80%), with a significantly higher prevalence in females, but much more aggressive and with poorer outcomes in males. Despite a high survival rate, disease recurrence and metastasis remain significant issues. The elucidation and identification of molecular markers associated with PTC remains a prominent unmet need. Identification of these markers could aid in identifying early- stage disease, as well as patient prognosis, therapeutic approaches, and patient outcomes. Long intergenic non-coding RNA (lincRNA) molecules comprise the largest subclass of RNA molecules within the human genome, yet the majority of their functions are yet to be identified. Evidence supports that these non-coding RNA molecules play a role in the regulation of gene expression, and have recently been identified as major players in cancer development and progression when aberrantly expressed. This deems lincRNAs as potential biomarkers and/or therapeutic targets, making them important for further study. Data from our lab identified LINC01614 as being significantly upregulated (~12-fold increase) in PTC, when compared to normal thyroid tissue. There was also ~30- fold increase in LINC01614 in male PTC when compared to females, highlighting potential sex-related correlation for study. Thus, this thesis focuses on the beginning study of LINC01614 as a potential biomarker for diagnosis and prognosis, as well as a target for therapeutic intervention. To develop our cellular model, LINC01614 was found to be upregulated in thyroid cancer cell line TPC1 (~5-fold) compared to the “normal”, immortalized thyroid cancer cell line (Nthy-ori-3-1). To decipher a phenotype for LINC01614 upregulation in PTC, we utilized the CRISPRi technique to decrease its expression in TPC1. The knockdown of LINC01614 resulted in a reduction in proliferation, migration, clonogenicity, and cell viability in TPC1 cells. Exploring the role that lincRNAs have in cancer phenotypes can lead to a plethora of different molecular markers for therapeutic intervention. The mechanisms by which these non-coding molecules regulate the expression of genes and other elements of the cellular milieu can serve as an open avenue for understanding how they impact PTC development and progression
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