1,721,917 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Supplemental Material - Using combination of albumin to fibrinogen ratio and prognostic nutritional index model for predicting disease activity in patients with systemic lupus erythematosus
No full textSupplemental Material for What Do We Know About people’s Politics? Testing a New Framework for Understanding Different Conceptions of Politics by Hongshuai Zhao, Zikun Huang, Shiqian Wang, Peng Fu, Biqi Fu, Yang Guo, Junming Li, and Qing Luo in Lupus</p
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Single-cell analysis on specification of mammalian germline and its role in health and diseases
No full textGerm cell specification is the first step for developing reproductive cells. The specification requires formative pluripotent stem cells as precursors. Previous attempts to capture formative pluripotency used opposite manipulation of Wnt signaling, activating or inhibiting, and achieved two distinctive states that indicated two ends of the formative pluripotency spectrum. Study I explored the role of Wnt signaling in the formative pluripotency spectrum. We produced a new form of formative pluripotency in epiblast-like stem cells (EpiLSCs) with activation of Wnt. We developed a computational single-cell method for transcriptionally aligning various cell lines within the formative pluripotency spectrum. Our analysis highlighted that EpiLSCs filled the gap in the pluripotency spectrum between previously published cell lines. Additionally, we revealed context-dependent roles of Wnt signaling in sustaining pluripotency and facilitating differentiation at the two ends of the formative pluripotency spectrum.Female germ cell specification in humans generally exhibits lower efficiencies than males in vitro. Human X chromosome inactivation has a large extent of incompleteness, resulting in escapees. Whether the female lower efficiencies are related to X-linked escapees is unknown. Study II investigated the influence of Xlinked escapees on germ cell specification in females and individuals with Klinefelter syndrome (KS), a condition typically characterized by an extra copy of the X chromosome and infertility. Through RNA sequencing and functional assays, we identified critical X-linked escapees, CHRDL1, IGSF1, and USP9X, inhibiting germ cell specification in females and KS. We found that USP9X elevated SOX2 to repress oxidative phosphorylation, promote mitochondria fusion and clustering, and perturb SOX17's regulation, exerting a profound reduction in germ cell specification.Germ cells carry both genetic and epigenetic information. Sperm's small RNA composition is shaped by the soma-to-germline communication pathway and, therefore, is responsive to environmental exposure. Polycystic ovary syndrome (PCOS) is an epigenetically heritable disorder affecting female offspring. The possibility of PCOS equivalent in males has prompted questions about the potential impact on male offspring and whether sperm small RNA plays a role in it. In study III, using a Swedish registered cohort, a Chile longitudinal cohort, and a mouse model, we found that women with PCOS transgenerationally transmitted reproductive and metabolic dysfunction into their male offspring. Using small RNA sequencing, we identified transgenerationally altered sperm small RNA in the mice, which overlapped with changes in the sons of women with PCOS, suggesting potential mechanistic parallels of inheritance between mice and humans.In this thesis, we uncover critical insights into the Wnt's context-dependent roles in the formative pluripotency spectrum, the repression of XCI escapees on germ cell development, and sperm small RNAs' transgenerational transmission. Additionally, this research paves the way for further exploration into germ cell development for individuals with KS and the inheritance of PCOS in male offspring, offering potential avenues for therapeutic interventions.List of scientific papersI. QING LUO, Han-Pin Pui, Jiayu Chen, Leqian Yu, Paulo R Jannig, Yu Pei, Linxuan Zhao, Xingqi Chen, Sophie Petropoulos, Jorge L Ruas, Jun Wu, Qiaolin Deng. Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence. Cell Reports. 2023 Jan 31;42(1):112021. (QL and HP contributed equally to this work.) https://doi.org/10.1016/j.celrep.2023.112021 II. Wenteng He, QING LUO, Jian Zhao, Allan Zhao, Luohua Feng, Ahmed Reda, Eva Lindgren, Jan-Bernd Strukenborg, Qiaolin Deng. SOX2 upregulation as downstream of X-linked gene dosage affects the specification of human primordial germ cell-like cells. (WH and QL contributed equally to this work.) [Manuscript]III. Sanjiv Risal , Congru Li, QING LUO, Romina Fornes, Haojiang Lu, Gustaw Eriksson, Maria Manti, Claes Ohlsson, Eva Lindgren, Nicolas Crisosto, Manuel Maliqueo, Barbara Echiburú, Sergio Recabarren, Teresa Sir Petermann, Anna Benrick, Nele Brusselaers, Jie Qiao, Qiaolin Deng, Elisabet Stener-Victorin. Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome. Cell Reports Medicine. 2023 May 16;4(5):101035. (SR, CL, QL and RF contributed equally to this work.) https://doi.org/10.1016/j.xcrm.2023.101035 </p
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Supplemental Material - Prognostic Value of Different Versions of the Model for End-Stage Liver Disease Score in Patients Undergoing Percutaneous Coronary Intervention
No full textSupplemental Material for Prognostic Value of Different Versions of the Model for End-Stage Liver Disease Score in Patients Undergoing Percutaneous Coronary Intervention by Hao-ming He, Chen He, Zhe-bin You, Si-cheng Zhang, Xue-qin Lin, Man-qing Luo, Mao-qing Lin, Li-wei Zhang, Kai-yang Lin, and Yan-song Guo in Angiology</p
- …
