1,046 research outputs found

    Needle-like instruments for steering through solid organs: A review of the scientific and patent literature

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    High accuracy and precision in reaching target locations inside the human body is necessary for the success of percutaneous procedures, such as tissue sample removal (biopsy), brachytherapy, and localized drug delivery. Flexible steerable needles may allow the surgeon to reach targets deep inside solid organs while avoiding sensitive structures (e.g. blood vessels). This article provides a systematic classification of possible mechanical solutions for three-dimensional steering through solid organs. A scientific and patent literature search of steerable instrument designs was conducted using Scopus and Web of Science Derwent Innovations Index patent database, respectively. First, we distinguished between mechanisms in which deflection is induced by the pre-defined shape of the instrument versus mechanisms in which an actuator changes the deflection angle of the instrument on demand. Second, we distinguished between mechanisms deflecting in one versus two planes. The combination of deflection method and number of deflection planes led to eight logically derived mechanical solutions for three-dimensional steering, of which one was dismissed because it was considered meaningless. Next, we classified the instrument designs retrieved from the scientific and patent literature into the identified solutions. We found papers and patents describing instrument designs for six of the seven solutions. We did not find papers or patents describing instruments that steer in one-plane on-demand via an actuator and in a perpendicular plane with a pre-defined deflection angle via a bevel tip or a pre-curved configuration.Accepted Author ManuscriptMedical Instruments & Bio-Inspired Technolog

    Design and preliminary evaluation of a bio-inspired steerable needle

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    Abstract 07.03 - Session Medical RoboticsMedical Instruments & Bio-Inspired Technolog

    Ovipositor-inspired steerable needle: design and preliminary experimental evaluation

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    Flexible steerable needles have the potential to allow surgeons to reach deep targets inside the human body with higher accuracy than rigid needles do. Furthermore, by maneuvering around critical anatomical structures, steerable needles could limit the risk of tissue damage. However, the design of a thin needle (e.g., diameter under 2 mm) with a multi-direction steering mechanism is challenging. The goal of this paper is to outline the design and experimental evaluation of a biologically inspired needle with a diameter under 2 mm that advances through straight and curved trajectories in a soft substrate without being pushed, without buckling, and without the need of axial rotation. The needle design, inspired by the ovipositor of parasitoid wasps, consisted of seven Nickel Titanium wires and had a total diameter of 1.2 mm. The motion of the needle was tested in gelatin phantoms. Forward motion of the needle was evaluated based on the lag between the actual and the desired insertion depth of the needle. Steering was evaluated based on the radius of curvature of a circle fitted to the needle centerline and on the ratio of the needle deflection from the straight path to the insertion depth. The needle moved forward inside the gelatin with a lag of 0.21 (single wire actuation) and 0.34 (double wire actuation) and achieved a maximum curvature of 0.0184 cm-1and a deflection-to-insertion ratio of 0.0778. The proposed biologically inspired needle design is a relevant step towards the development of thin needles for percutaneous interventions.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Medical Instruments & Bio-Inspired Technolog

    A funeral handkerchief [electronic resource] : in two parts : I. Part, containing arguments to comfort us at death of friends, II. Part, containing several uses which we ought to make of such losses : to which is added, Three sermons preached at Coventry /

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    The 2nd part has special t.p., continuous paging, and imprint: London : Printed for the author, 1691.Errata: prelim. p. [15].Imperfect: t.p. to the "Three sermons preached at Coventry" lacking.Includes bibliographical references.Reproduction of original in Huntington Library.WingElectronic reproduction

    Voice Compression and Communications: Principles and Applications for Fixes and Wireless Channels

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    Up-to-date, expert coverage of topics in wireless voice communications Voice communication is the most important facet of mobile radio service. Even when the predicted surge of wireless data and Internet services becomes a reality, voice will remain the most natural means of human communication. Voice Compression and Communications details issues in wireless voice communications and treats compression, channel coding, and wireless transmission as a joint subject. Part I covers background material, whereas Part II provides detailed information on both proprietary and standardized analysis-by-synthesis codecs, including the speech codecs of virtually all existing wireline-based and wireless systems. Parts III and IV discuss mainly research-based wideband, audio, as well as very low-rate schemes likely to find their way into future standards. Voice Compression and Communications describes fundamental concepts in a non-mathematical way early in the book for those with only a background knowledge of signal processing and communications. More advanced readers will find detailed discussions of theoretical principles, future concepts, and solutions to various specific wireless voice communications problems

    Book Review: Khlynina T.P., Krinko E.F. History, Politics and Nation Building in the North Caucasus: Monograph. – Rostov-on-Don, Izd-vo YuNTs RAN, 2014. – 434 p.

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    The author of the review reveals the research approach of the monograph’s authors – T.P. Khlynina and E.F. Krinko to the analysis of the interconnection of historical memory, politics and nation building in the North Caucasus. The author also reveals the argumentation of authors’ evaluations of Soviet nation building in the region, interactions of state power with ethnopolitical movements, methods of historical memory institutionalization in the North Caucasus

    Remarks upon the occasional paper, number VIII [electronic resource] : in a letter to the author.

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    Caption title.Place and date of publicatin suggested by Wing."The 'author' is Richard Willis"--NUC pre-1956 imprints.Imperfect: t.p. stained with loss of print.Reproduction of original in the Huntington Library.WingElectronic reproduction

    Love is in the stomach, not the heart /

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    Advertisements for other works by author: [3] p. at end.On verso of t.p.: Vincent Dill, Electrotyper, N.Y.In verse and prose.Mode of access: Internet

    Satan chained : a poem /

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    On t.p.: "Published by subscription, and for the benefit of the author."On verso of t.p.: S.F. Phelps, printer ..., N.Y.Mode of access: Internet

    The czar : a tale of the time of the first Napoleon /

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    Added t.p., illustrated.Mode of access: Internet
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