131,445 research outputs found

    Acute anaphylaxis following exercise stress testing

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    The definitive version is available at www.blackwell-synergy.comP. J. Psaltis, B. K. Dundon, D. P. Leon

    Second-harmonic radiating imaging probes and harmonic holography

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    Compared with other imaging probes such as fluorescent dyes and quantum dots, second-harmonic radiating imaging probes (SHRIMPs) provide a unique ultrafast, coherent optical contrast that is free of photobleaching and emission intermittency. Using the second-harmonic signal emitted from SHRIMPs, harmonic holography achieves three-dimensional holographic imaging with a color contrast similar to fluorescence microscopy where the uninterested background scattering is efficiently suppressed by an optical filter. The coherent contrast provided by SHRIMPs also enables imaging through turbid media via digital phase conjugation. Here we review the developments and applications of SHRIMPs and harmonic holography.L

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    "Closing the R&D Gap, Evaluating the Sources of R&D Spending"

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    Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.

    Digital reverse propagation in focusing Kerr media

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    Lenses allow the formation of clear images in homogeneous linear media. Holography is an alternative imaging method, but its use is limited to cases in which it provides an advantage, such as three-dimensional imaging. In nonlinear media, lenses no longer work. The light produces intensity-dependent aberrations. The reverse propagation method used in digital holography to form images from recorded holograms works even in Kerr media [M. Tsang, D. Psaltis, and F. G. Omenetto, Opt. Lett. 28, 1873 (2003).]. The principle has been experimentally demonstrated recently in defocusing media [C. Barsi, W. Wan, and J.W. Fleischer, Nat. Photonics 3, 211 (2009).]. Here, we report experimental results in focusing media.L

    A. D. Fricke, author

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    Black and white photograph of author, A. D. Fricke

    Comparison between three-dimensional angiographic reconstruction and intravascular ultrasound: imaging of the left main coronary artery

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    Abstract not availableDaniel B. Spoon, Ronen Rubinshtein, Peter J. Psaltis, Gupreet S. Sandhu, Ryan Lennon, Charanjit S. Rihal and Amir Lerma
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