170,478 research outputs found
Cardiogenic shock in a young woman
No full textRoberts-Thomson, Kurt C. ; Psaltis, Peter J. ; DeAngelis, Enz
Association of intracellular Staphylococcus aureus with prognosis in chronic rhinosinusitis
No full textAbstract not availableJudy Ou, Amanda Drilling, Deepti Singhal, Neil C.-W. Tan, Deanna Wallis-Hill, Sarah Vreugde, Alkis J. Psaltis, and Peter-John Wormal
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Social Relations, the Financial Crisis and Human Development
No full textIn this chapter, from a socio-psychological perspective I consider how social interactions and relations and intergroup relations
are affected by economic, political, and cultural factors. In particular, by a review of some recent literature the effects of the current financial crisis on the way people interact
with the others is inspected. Moreover, as Bauman (2007) pointed out in this last decade there was a cultural transformation in so-called Western countries by which people give a great emphasis to consumption and ego-individuality
as a way of living. Ehrenberg (2010) explained the malaise of present-day societies by looking to the large spread of some diseases (e.g. narcissism) in many parts of the population. These “syndromes” should be considered as more social than pathological phenomena as they are linked to a certain
transformation of cultural and social values. Moreover, some scholars (e.g. Finkel & Moghaddam, 2005; Passini, 2011) have pointed out that we live in an “age of rights:” i.e., people attach priority to their individual rights and liberties within a narrow-minded, individualistic world-view and de-emphasize
their duties and responsibilities. This world-view supports a shift of responsibility outside the individual itself, by which others are only considered in terms of being a burden and an impediment, instead of presenting the opportunity to help achieve one’s own individuality. Finally, in the conclusions of the chapter, some aspects that may oppose this "sick" drift of the society
are discussed. In particular, concepts as democratic individualism (Dewey, 1930) – as opposed to a possessive individuality (Macpherson, 1964) – vertical responsibility (Jonas, 1984), and generativity (Erickson, 1950) are introduced
Digital reverse propagation in focusing Kerr media
No full textLenses allow the formation of clear images in homogeneous linear media. Holography is an alternative imaging method, but its use is limited to cases in which it provides an advantage, such as three-dimensional imaging. In nonlinear media, lenses no longer work. The light produces intensity-dependent aberrations. The reverse propagation method used in digital holography to form images from recorded holograms works even in Kerr media [M. Tsang, D. Psaltis, and F. G. Omenetto, Opt. Lett. 28, 1873 (2003).]. The principle has been experimentally demonstrated recently in defocusing media [C. Barsi, W. Wan, and J.W. Fleischer, Nat. Photonics 3, 211 (2009).]. Here, we report experimental results in focusing media.L
Comparison between three-dimensional angiographic reconstruction and intravascular ultrasound: imaging of the left main coronary artery
No full textAbstract not availableDaniel B. Spoon, Ronen Rubinshtein, Peter J. Psaltis, Gupreet S. Sandhu, Ryan Lennon, Charanjit S. Rihal and Amir Lerma
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
A compact optofluidic microscope
No full textWe demonstrate a novel optical imaging device that can be directly integrated into a microfluidic network, and therefore enables on-chip imaging in a microfluidic system. This micro imaging device, termed optofluidic microscope (OFM) is free of bulk optics and is based on a nanohole array defined in a non-transmissive metallic layer that is patterned onto the floor of the microfluidic channel. The operation of the optofluidic microscope will be explained in details and its performance is examined by using a popular animal model, Caenorhabditis elegans (C. elegans). Images from a large population of nematode worms are efficiently acquired within a short time frame. The quality of the OFM images of C. elegans and the morphological characteristics revealed therein are evaluated. Two groups of early-stage C. elegans larvae, wild-type and dpy-24 are successfully separated even though their morphological difference at the larval stage is subtle. The experimental results support our claim that the methodology described therein can be effectively used to develop a powerful tool for fulfilling high-resolution, high-throughput imaging task in microfluidics-based systems
Manuka honey sinus irrigations in recalcitrant chronic rhinosinusitis: phase 1 randomized, single‐blinded, placebo‐controlled trial
No full textAbstract not availableMian Li Ooi, Arvind Jothin, Catherine Bennett, Eng H. Ooi, Sarah Vreugde, Alkis J. Psaltis and Peter-John Wormal
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