104 research outputs found
Supplemental Material, Cronbachs_alhpa_data - Evaluation of Counseling Practices and Patient’s Satisfaction Offered by Pharmacists for Diabetics Attending Outpatient Pharmacies in Al Ahsa
No full textSupplemental Material, Cronbachs_alhpa_data for Evaluation of Counseling Practices and Patient’s Satisfaction Offered by Pharmacists for Diabetics Attending Outpatient Pharmacies in Al Ahsa by Promise M Emeka, Manea Fares AlMunjem, Sahibzada Tasleem Rasool and Noor Kamil in Journal of Patient Experience</p
Supplemental Material, Revised_Research_Quesionnaire_after_testing_(1) - Evaluation of Counseling Practices and Patient’s Satisfaction Offered by Pharmacists for Diabetics Attending Outpatient Pharmacies in Al Ahsa
No full textSupplemental Material, Revised_Research_Quesionnaire_after_testing_(1) for Evaluation of Counseling Practices and Patient’s Satisfaction Offered by Pharmacists for Diabetics Attending Outpatient Pharmacies in Al Ahsa by Promise M Emeka, Manea Fares AlMunjem, Sahibzada Tasleem Rasool and Noor Kamil in Journal of Patient Experience</p
Effect of Cooperative Learning Strategy on Secondary School Students’ Achievement in Commerce in Enugu State, Nigeria
No full textThe study investigated the effect of Cooperative Learning Strategy on Secondary School Students Achievement in Commerce in Enugu State. The design adopted for the study was quasi experimental, precisely pretest, Posttest non-equivalent control/group. Two research questions and three null hypotheses guided the study. The population for the study consisted of 450 SSS one students who offered commerce in 2019/2020 academic year in Enugu State, Nigeria. The sample consisted of eighty students (40 males and 40 females) drawn from the target population using sample random sampling technique. The instrument used for data collection was Commerce Achievement Test (CAT). The instrument was face and content validated by three experts. The instrument was further tested on 20 Senior Secondary School one students similar to those used for the study in Ebonyi State. The researcher adopted the Kudar Richardson formula (K-R20) in determining the pre-CAT and post-CAST hence yielded reliability coefficient of 0.65. Mean and standard deviation was used in answering research questions. Hypotheses were tested using Analysis of covariance (ANCOVA) at 0.5 level of significance. The study revealed that: students taught commerce using cooperative method performed better than their counterparts using conventional method. It also revealed that male students achieved higher than their female when taught commerce using cooperative learning strategy. Based on the findings, it was recommended among others that government should make cooperative teaching strategy compulsory. Keywords: Commerce, Cooperative strategy, secondary School and achievement. DOI: 10.7176/EJBM/14-14-11 Publication date:July 31st 202
Effect of Cooperative Teaching Method on Senior Secondary School Students’ Achievement and Retention in Financial Accounting in Enugu State
No full textThis study empirically investigated the effect of Cooperative teaching Method on Senior Secondary School Students’ Achievement and Retention in Financial Accounting in Enugu State. Four research questions and six hypotheses guided the study. Pretest-posttest non-randomized control group design was adopted for the study. The study was conducted in Agbani Education zone of Enugu State. The population for the study consisted of all co-educational senior secondary school one students who are offering Financial Accounting in Agbani Educational Zone of Enugu State numbering 300 whereas a sample of 165; 110 females and 55 males senior secondary school one students were drawn from (two intact classes). The cooperative group (experimental) consisted of 30 males and 85 females group totally 115 and 15 males and 30 females for controlled group. Techniques adopted for sampling was purposive multislage random sampling. Instrument used for data collection was Financial Accounting Achievement Test (FAAT) consisting of 60 item quwstions adopted from past WAEC and NECO question papers. The instrument was face and content validated by three experts. The instrument used was further tested on 20 senior secondary school one students similar to those used for the study in another Educational Zone. The researcher adopted the Kuder Richardson Formula (K-R20) in determining the pre-FAAT and post-FAAT hence yielded reliability coefficient of 0.68. Mean and standard deviation was used in answering research questions. Hypotheses were tested using Analysis of Covariance (ANCOVA) at 0.05 level of significance. The study revealed that the experimental group (cooperative group) achieved higher and retained more Financial Accounting than their counterparts in the control group. Also male and female students did not differ significantly in their achievement and retention in Financial Accounting. It was recommended that cooperative method should be used in teaching financial Accounting. Again, financial Accounting teachers should be encouraged to embark on regular training and retraining on the effective use of cooperative learning in the classroom. Keywords: Financial Accounting, Cooperative method, Secondary School, Achievement and Retention. DOI: 10.7176/JEP/12-27-13 Publication date:September 30th 202
Digital Skills Possessed by Secretaries for Effective Management of Information in Enugu State, Nigeria
No full textThis study was carried out to determine the digital skills possessed by secretaries for effective management of information in Enugu State. A survey research design was used for the study. Two research questions and two null hypotheses guided the study. The population of the study consisted of 365 employers of secretaries in the private and public establishments. There was no sampling since the population was not too large. The instrument for data collection was a 35 item questionnaire titled “Digital Skills Possessed by Secretaries Questionnaire (DSPBSQ) developed by the researcher. Three experts duly validated the instrument. The reliability was done using Cronbach Alpha which yielded coefficient of 0.78, indicating the instrument was reliable. The two research questions were answered using mean with standard deviation while the null hypotheses were tested at .05 level of significance using the two-way ANOVA. Results of the study showed that: Basic digital skills are highly possessed by secretaries in both private and public establishments in Enugu State for effective management of information. The result also revealed that advanced digital skills are fairly possessed by secretaries in both private and public establishments in Enugu State for effective management of information. Based on the findings, it was recommended that, there should be regular seminars and workshops skills for secretaries. Again, employers of labour should provide ICT’s to their secretaries as working tools. Keywords: Digital Skills, Secretaries, Effective Management and Information DOI: 10.7176/IKM/11-4-11 Publication date:September 30th 202
Effect of metformin on ECG, HR and BP of rats administered with cardiotoxic agent doxorubicin
No full textBackground: Cardiovascular complications during drug therapy is worrisome and has been known to increase morbidity and mortality. The aim of this study was to investigate the effect of metformin on BP, HR, and ECG, after subacute administration of doxorubicin in rats.Methods: Laboratory acclimatised animals were divided into 4 experimental groups consisting of group I as the control, given 0.5ml normal saline. Group II, received 3mg/kg doxorubicin on alternate days, while group III was given 300mg/kg metformin. The last group of animals were treated with 300mg/kg metformin, 30 min later, the animals were injected doxorubicin ip. The treatment lasted for 15 days thereafter, ECG, HR and BP were measured with anaesthesia.Results: Result showed that doxorubicin induced ECG changes in terms of increased PR and QT intervals significantly. Whereas, QRS and RR intervals were at same time significantly decreased. Metformin was observed to significantly attenuate these changes. In addition, metformin restored decreases in HR that was caused by doxorubicin in a significant fashion. However, metformin alone produced a decrease in HR compared with control. The observed reduced SBP and DBP produced by doxorubicin were also alleviated by the administration of metformin. There were increases in BP parameters measured in normotensive rats with metformin alone.Conclusions: In conclusion, metformin was found to attenuate doxorubicin-induced alteration in ECG pattern and restored the mechanical and physiological functions of the rat heart. Our data further suggests monitoring of CVS changes such as ECG particularly with drugs known to cause myocardial injury. </jats:p
Virtual Screening and Meta-Analysis Approach Identifies Factors for Inversion Stimulation (Fis) and Other Genes Responsible for Biofilm Production in Pseudomonas aeruginosa: A Corneal Pathogen
No full textBacterial keratitis caused by Pseudomonas aeruginosa is indeed a serious concern due to its potential to cause blindness and its resistance to antibiotics, partly attributed to biofilm formation and cytotoxicity to the cornea. The present study uses a meta-analysis of a transcriptomics dataset to identify important genes and pathways in biofilm formation of P. aeruginosa induced keratitis. By combining data from several studies, meta-analysis can enhance statistical power and robustness, enabling the identification of 83 differentially expressed candidate genes, including fis that could serve as therapeutic targets. The approach of combining meta-analysis with virtual screening and in vitro methods provides a comprehensive strategy for identifying potential target genes and pathways crucial for bacterial biofilm formation and development anti-biofilm medications against P. aeruginosa infections. The study identified 83 candidate genes that exhibited differential expression in the biofilm state, with fis proposed as an ideal target for therapy for P. aeruginosa biofilm formation. These techniques, meta-analysis, virtual screening, and invitro methods were used in combination to diagnostically identify these genes, which play a significant role in biofilms. This finding has highlighted a hallmark target list for P. aeruginosa anti-biofilm potential treatments
The Role of Pseudomonas aeruginosa in the Pathogenesis of Corneal Ulcer, Its Associated Virulence Factors, and Suggested Novel Treatment Approaches
No full textBackground: Pseudomonas aeruginosa (P. aeruginosa), is a diverse Gram-negative pathogen commonly associated with a wide spectrum of infections. It is indicated to be the most prevalent causative agent in the development of bacterial keratitis linked with the use of contact lens. Corneal infections attributed to P. aeruginosa frequently have poor clinical outcomes necessitating lengthy and costly therapies. Therefore, this review looks at the aetiology of P. aeruginosa bacterial keratitis as well as the bacterial drivers of its virulence and the potential therapeutics on the horizon. Method: A literature review with the articles used for the review searched for and retrieved from PubMed, Scopus, and Google Scholar (date last accessed 1 April 2024). The keywords used for the search criteria were “Pseudomonas and keratitis, biofilm and cornea as well as P. aeruginosa”. Results: P. aeruginosa is implicated in the pathogenesis of bacterial keratitis associated with contact lens usage. To reduce the potential seriousness of these infections, a variety of contact lens-cleaning options are available. However, continuous exposure to a range of antibiotics doses, from sub-inhibitory to inhibitory, has been shown to lead to the development of resistance to both antibiotics and disinfectant. Generally, there is a global public health concern regarding the rise of difficult-to-treat infections, particularly in the case of P. aeruginosa virulence in ocular infections. This study of the basic pathogenesis of a prevalent P. aeruginosa strain is therefore implicated in keratitis. To this effect, anti-virulence methods and phage therapy are being researched and developed in response to increasing antibiotic resistance. Conclusion: This review has shown P. aeruginosa to be a significant cause of bacterial keratitis, particularly among users of contact lens. It also revealed treatment options, their advantages, and their drawbacks, including prospective candidates
RELEVANCE OF SECONDARY SCHOOL ACCOUNTING CURRICULUM TO THE JOBS PERFORMED BY ENTRY-LEVEL ACCOUNTING SECONDARY SCHOOL GRADUATES IN ENUGU STATE
No full textThis study was carried out to determine relevance of secondary school accountingcurriculum to the jobs performed by entry-level accounting secondary school graduates inEnugu State. Two research questions guided the study. The study adopted survey researchdesign. The population of the study was 144 accounting supervisors in both private andpublic establishments in Enugu State. The instrument for data collection was a 100 itemquestionnaire which was developed by the researcher. The instrument was duly validated bythree (3) expertsin test and measurement which yielded a reliability coefficient of 0.69 usingcronbach. Research questions were answered using mean and standard deviation, while thenull hypotheses were tested at 0.05 level ofsignificance using t-test statistic. It wasfound outfrom the study that out of 50 content areas in secondary school accounting curriculum, 28were relevant in securing accounting positions in business officesin Enugu State. It was alsofound out from the study that 28 out of 50 items were jobs performed by entry-levelsecondary school graduates in business offices in Enugu State. Based on the findings, it wasrecommended that educators and curriculum planners should work closely withestablishments to develop current curricula content for schools. Accounting tutors shouldalso be given the opportunity to work in accounting offices during long vacations to enablethemup-date their knowledge
Perception Of Office Managers on Technology Skills Possessed of Secretaries in Colleges of Education for Managing Information in Enugu State
No full textThe study was undertaken to determine the perception of office managers on technology skills possessed by secretariats in colleges of education for managing information in Enugu State. The researcher employed a descriptive survey research design. The study population consisted of 90 office managers from two government owned colleges of education in Enugu State. There was no sampling since the size was manageable. The instrument for the data collection was a structured questionnaire developed by the researcher entitled: “Technology Skills Possessed” by Secretaries Questionnaire (TSPSQ). The instrument was duly validated by three experts. The reliability was done using Cronbach Alpha which yielded coefficient of 0.68; indicating the instrument was reliable. The two research questions was answered using mean with standard deviation. While the null hypotheses were tested at .05 level of significance using t-test. Results of data analysis relating to the study have shown the following. Networking skills are highly possessed by secretaries as perceived by office managers in colleges of Education for managing information in Enugu State. The office managers equally perceived that word processing skills are highly possessed by their secretaries for managing information. The hypotheses tested, showed that there was no significant difference between office managers in federal colleges of education and their counterparts in state on their perception on technology skills possessed by their secretaries for managing information. Based on the findings, it was recommended that secretaries should be allowed to update their technology skills by attending regular conferences. Keyword: Office Managers, Technology Skills, Secretaries and Colleges of Education. DOI: 10.7176/EJBM/13-18-14 Publication date:September 30th 202
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