1,720,956 research outputs found
Glioma histology at charlotte Maxeke Johannesburg academic hospital, a five year retrospective study
No full textA research report submitted in partial fulfillment of the requirements for the degree of Master of Medicine in Neurosurgery to the Faculty of Health Sciences, School of Clinical Medicine, University of Witwatersrand, Johannesburg 2024The epidemiology of gliomas has been described thoroughly by developed countries worldwide but information regarding gliomas is limited in developing countries including in our local setting in South Africa. This study will be describing glioma histology and the demographics of patients with gliomas for patients diagnosed at Charlotte Maxeke Johannesburg Academic Hospital (CMJAH) situated in Johannesburg South Africa.
The records of 44 patients ages between 12 and 70 years with histologically confirmed glioma from 2015 to 2919 was reviewed and our findings are as follows; In our sector we see more Black population than White, Coloured and Asians combined. Despite that literature commonly report gliomas to be more prevalent in males than females, we found females to be more prevalent than males (ratio 1,3:1) in our study group with males only showing prevalence over females with the advanced age group of 60 to 70 years.
Our mean age of glioma diagnosis is younger (43years) than the documented age group and we found the mean age to be even younger with patients confirmed HIV (38 years). The study demonstrated that females were diagnosed at early average age of 40 year and males average age of 47 years. In keeping with literature glioblastoma is the most common glioma in our study population. We also found gliomas to be more prevalent supratentorial in the temporal lobe than infratentorial and other lobes respectively in our study population. Patients with higher grade gliomas presented with varied number of symptoms than lower
grade.
With regard to biopsy procedures, most of our cases had undergone minimal invasive stereotactic biopsy and about seventy percent of the frozen biopsy cases were of patients who had minimal invasive stereotactic biopsy and only thirty percent had open biopsy. The study found that glioma size increased with increase in glioma grade and patients who are HIV positive. There was no significant relationship found between patients’ age groups and glioma size.
We found that immunochemistry is widely done , but molecular testing lacking behind with testing only started late 2017 and improving annually. For patients with HIV it was found that grade III gliomas are the most prevalent. Glioma grade increase with increase in age group and in patients wo are confirmed HIV positive. A formal national registry for gliomas will help to determine disease demographics, distribution, frequencies and associations for early detection and patients management strategies.MM202
Single surgeon series of myelomeningocoele repairs: factors influencing outcomes
Get PDFA research report submitted to the Faculty of Health Sciences, University of the
Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of
Master of Medicine in Neurosurgery.
Johannesburg, 2018.This study reports on 24 Myelomeningocoeles (MMC) repaired at Chris Hani
Baragwanath Hospital by a single surgeon.
Mean gestation was 38.13 weeks, most MMCs were in the lumbosacral region and
mean MMC surface area was 19.4cm2. Cerebrospinal Fluid (CSF) leak at birth was
present in 50%, lower-limb neurology in 71%, lower cranial nerve dysfunction in 13%
and hydrocephalus in 54%. Clubfoot was present in 71%, congenital hip dysplasia
in 24%, neurogenic bladder in 82% and cutaneous abnormalities in 12%.
Mean time from birth to MMC repair was 13.6 days, 46% of infants had
ventriculoperitoneal shunt insertion and latex allergy was absent.
Complication wise, wound dehiscence arose in 21%, CSF leak in 12.5% and
infection in 25%. Neonates with CSF leak subsequently developed both wound
dehiscence and CSF infection.
Maternal HIV prevalence within the series was 28% and there was potential
correlation between CSF infection and birth to a positive mother.LG201
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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