173,222 research outputs found
Serious Play on the Fringes of Empire: Zoë Wicomb, Thomas Pringle, and the Transnational Author
Discusses the novel Still Life (2020) by the Scottish/South African writer Zoë Wicomb, which portrays a contemporary novelist researching the life and significance of the Scottish/South African poet Thomas Pringle (1789-1834) through an imaginative collaboration with an early 20th century bellelettristic biographer (referencing Virginia Woolf\u27s imaginative biography Orlando) and with the intervention of two African figures Pringle believed himself to have liberated, the West Indian ex-slave Mary Prince (c. 1788-1833) and Hinza, the Tswana boy memorialized in one of Pringle\u27s best-known South African poems, suggesting that Wicomb\u27s novel (and her oeuvre) present an important transnational version of authorial identity of wider significance in the current development of Scottish literary studies [PGS]
The Christian buildings of Ramla.
This chapter discusses the historical and architectural evidence relating to the Christian buildings of Ramla between the time of its foundation c.715 and 1917
Ischemic preconditioning attenuates portal venous plasma concentrations of purines following warm liver ischemia in man
Background/Aims: Degradation of adenine nucleotides to adenosine has been suggested to play a critical role in ischemic preconditioning (IPC). Thus, we questioned in patients undergoing partial hepatectomy whether (i) IPC will increase plasma purine catabolites and whether (ii) formation of purines in response to vascular clamping (Pringle maneuver) can be attenuated by prior IPC. Methods: 75 patients were randomly assigned to three groups: group I underwent hepatectomy without vascular clamping; group II was subjected to the Pringle maneuver during resection, and group III was preconditioned (10 min ischemia and 10 min reperfusion) prior to the Pringle maneuver for resection. Central, portal venous and arterial plasma concentrations of adenosine, inosine, hypoxanthine and xanthine were determined by high-performance liquid chromatography. Results: Duration of the Pringle maneuver did not differ between patients with or without IPC. Surgery without vascular clamping had only a minor effect on plasma purine transiently increased. After the Pringle maneuver alone, purine plasma concentrations were most increased. This strong rise in plasma purines caused by the Pringle maneuver, however, was significantly attenuated by IPC. When portal venous minus arterial concentration difference was calculated for inosine or hypoxanthine, the respective differences became positive in patients subjected to the Pringle maneuver and were completely prevented by preconditioning. Conclusion: These data demonstrate that (i) IPC increases formation of adenosine, and that (ii) the unwanted degradation of adenine nucleotides to purines caused by the Pringle maneuver can be attenuated by IPC. Because IPC also induces a decrease of portal venous minus arterial purine plasma concentration differences, IPC might possibly decrease disturbances in the energy metabolism in the intestine as well. Copyright (C) 2005 S. Karger AG, Basel
Augmenting the ablative effect of liver electrolysis: Using two electrodes and the Pringle maneuver
© Taylor & FrancisSeveral methods of liver tumor ablation have been investigated, and these include the novel technique of electrolysis. Electrolysis is slower than other forms of ablative therapy. This study determined methods of increasing the ablative effect of electrolysis. Domestic white pigs were divided. One group received electrolysis using two electrode catheters, and in the other group a concurrent intermittent Pringle maneuver was performed to induce intermittent ischemia. The effect of two electrode catheters versus a single electrode catheter was compared, and the effect of the Pringle maneuver versus no Pringle was examined with two electrode catheters. The livers were harvested, and the volume of each lesion was calculated. There was a linear relationship between the volume of hepatic necrosis and the electrolytic dose in (p <.005) in both the single-electrode-catheter and two-electrode-catheter groups. Comparison between the single- and multiple-electrode groups showed a highly significant difference in the dose response (p <.0000002) when more than one electrode was used. Use of the Pringle maneuver during electrolysis produced larger volumes of hepatic necrosis over all doses when using two electrode catheters. Rates of necrosis were 3.8 cm(3)/100 C for a single electrode catheter, 5.46 cm(3)/100 C for two electrode catheters without Pringle, and 6.17 cm(3)/100 C for electrolysis with two electrode catheters coupled with intermittent Pringle maneuver. Thus, electrolysis was both reliable and predictable in producing hepatic necrosis in a dose-dependent manner. The time delay in achieving tumor ablation via electrolysis can be overcome by using two electrodes combined with the Pringle maneuver to increase the volume of the lesion produced
March 13, 1910 Page four Leffel-Megerle wedding Easter greeting to my friend J. C. Pringle to enter government service
Leffel, Thomas W.; Megerle, Anna; Stoner, Winifred Sackville; Stoner, J. R.; Pringle, J. C.
The effects of the pringle maneuver on the pancreas: Can octreotide be protective?
Objective: The aim of this study was to evaluate the negative effects of the Pringle maneuver on pancreatic tissue with respect to the time of performing the maneuver. Moreover, the efficacy of octreotide therapy on pancreatic changes at the time of the Pringle maneuver was assessed. Animals: Fifty male Wistar Albino rats were randomized into 5 groups. Design: The groups were formed as follows: Group A: sham operation, Group B: Pringle maneuver for 30 min plus octreotide (PM30-OCT), Group C: Pringle maneuver for 60 min plus octreotide (PM60-OCT) and Group D: Pringle maneuver for 30 min plus 0.9 % saline solution (PM30-SS), Pringle maneuver for 60 min plus 0.9 % saline solution (PM60-SS, Group E). Main outcome measures: Blood samples for the evaluation of both amylase and lipase levels were taken via the portal vein. Levels of glutathione, glutathione reductase, catalase, myeloperoxidase, nitric oxide, xanthine oxidase, malondialdehyde, tumour necrosis factor alpha (TNF-alpha), and interleukin-1 beta (IL-1 beta) were assessed in the excised pancreatic tissue. Results: In the octreotide-treated groups, the catalase level was significantly higher in Group B (PM30-OCT) as compared to Group C (PM60-OCT). Amylase, lipase, NO and IL-1 beta levels were higher in Group C (PM60-OCT). In the saline solution-treated groups, the catalase level was significantly higher in Group E (PM60-SS) than in Group D (PM30-SS) while nitric oxide and glutathione levels were found to be significantly lower in Group E (PM60-SS) than in Group D (PM30-SS). Comparison of those groups using the Pringle maneuver for 30 minutes, the octreotide-treated group (Group B, PM30-OCT) was found to have a higher degree of edematous change than the saline-treated group (Group D, PM30-SS). Among the treatment groups, TNF-alpha expression decreased with increasing occlusion time. Conclusion: In this study, pancreatic damage and the duration of the Pringle maneuver are directly proportional to each other. Moreover, the administration of octreotide prior to the Pringle maneuver contributed to the pancreatic damage
March 13, 1910 Page four Leffel-Megerle wedding Easter greeting to my friend J. C. Pringle to enter government service
Leffel, Thomas W.; Megerle, Anna; Stoner, Winifred Sackville; Stoner, J. R.; Pringle, J. C.
Playing with ethics?: A Foucauldian examination of the construction ethical subjectivities in Ultimate Frisbee
Links between instrumental rationality and problematic sporting subjectivities are well established (e.g., Beamish & Ritchie, 2006; Donnelly, 1996; Hughes & Coakley, 1991). In recent years, however, critical scholars have taken an increasing interest in how athletes and coaches might find ways of problematizing their involvement in sport and thus discover new ways of understanding their participation (e.g., Denison, 2010; Douglas & Carless, 2006, 2009; Markula & Pringle, 2006; Pringle & Hickey, 2010; Shogan, 2007). Markula and Pringle (2006), Pringle and Hickey (2010), and Shogan (2007) have adopted a Foucauldian perspective to examine how those involved in sport and exercise might undertake a process of ethical self-creation.
This interest in the formation of ethical sporting subjectivities resonated closely with my own experiences as an athlete and coach, and, in particular, my experiences within the sport, Ultimate Frisbee (Ultimate). Subsequently, I was drawn to ask the Foucauldian question: “what forms of problematization and practices of self underpin Ultimate players’ creation of an ethical self through an aesthetics of existence?” To examine this question I undertook an ethnographic study of Ultimate, comprising two years of fieldwork as a participant-observer, interviews with fourteen Ultimate players and textual analysis of Ultimate media. I specifically sought to analyse my work using Foucauldian theory and the ethical turn within French postmodernism.
I found a heterogeneous process of ethical self-creation to be evident amongst Ultimate players. Of particular importance in this process were players’ multiple understandings of Spirit of the Game, which I interpreted as a postmodern telos, and their ongoing engagement in practices of self, which were “not something invented by the individual himself [sic]. [Rather] they are models he finds in his culture” (Foucault, 2000a, p. 291). However, I found that differences in players’ interpretations of these practices of self, in combination with a few players who appeared to reject these practices, meant Ultimate was not free from conflict, disagreement, or controversy. Ultimate, then, was not an ethical utopia; rather, it offered players possibilities to create their selves as ethical subjects. I added complexity to this understanding of ethics by reconsidering Ultimate through the ethics of the Other. Drawing on Derrida’s tactics of clôtural reading, aporia and justice, I theorized ethically problematic aspects of Ultimate which had not been revealed within my Foucauldian analysis.
In this thesis I support moves to integrate postmodern ethical perspectives and subjectivities within sociological studies of sport. Such analyses take seriously the ethical perspectives that individuals and groups have and seek to examine how these understandings influence their sense of self. At the same time, however, ethics is revealed to always be partial and incomplete. In this sense, ethics is a performative project without end. The sociology of ethics which I undertake in this thesis offers possibilities not only for understanding questions of how sporting subjectivities are currently created, but also for considering possibilities of how these subjectivities might be formed differently in the future.
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