1,720,967 research outputs found
Approach to bipolar spectrum and subthreshold mood disorders
No full textIn the last decades the concept of bipolar disorder was subjected to many revisions. The complexity in diagnosing mood disorders, on the other hand, stems from the problem to delineate the boundary of these morbid conditions. The current nosographic approach is limited by the lack of attention given to the natural course and to the longitudinal and family characteristics of patients suffering of mood disorders. Considering these limits, some authors developed different nosographic models to include other atypical, non-standardized characteristics of mood disorders. However, regardless of the efforts made so far, a gap in classification still remains, putting restrictions in the clinical and neurobiological range of activities
Haulage alternatives in a dolomitic limestone quarry for aggregates: a technical-economical and environmental comparison
No full textTowards a redefinition of dissociative spectrum dimensions inside Capgras and misidentification syndromes in bipolar disorder: case series and literature review
No full textIntroduction: Misidentification phenomena and Capgras Sym- drome (CS) occur in different psychiatric (psychotic or ma- jor affective illnesses) and neurological (traumatic brain injury, epilepsy, neurosyphilis, delirium, migraine, multiple sclerosis,arteriovenous malformation, tumor, stroke and dementia) disor- ders [1]. Patients with CS report that one or more well-known persons (usually familiy members) or even the patient himself have been replaced by a “double” or impostor. This core symp- tomatology may occur within nihilistic delusions of Cotard’s Syn- drome (the delusional perceptions of physical transformation or of not being alive) and can be accompanied by intermetamorphosis, autoscopy, heautoscopy, depersonalization and derealization as well as by erotomanic or jealousy delusions [2]. The aim of this report is to redefine dissociative spectrum dimensions inside CS and misidentification syndromes in patients with Bipolar Disorder (BD).Method: Five inpatients presenting with BD and CS were assessed with the SCID-P for Axis I diagnosis. As regards psy- chopathological evaluation, the patients were also administered the Structured Clinical Interview for Derealization and Depersonaliza- tion Spectrum (SCI-DER), the Depersonalization Severity Scale (DSS) for dissociative spectrum symptoms, the Hamilton Rating Scale for Depression (HRSD) to quantify depressive features as well as the Young Mania Rating Scale (YMRS) to measure manic symptoms. The SCI-DER was developed at the Departments of Psychiatry, Neurobiology, Pharmacology, and Biotechnologies of the University of Pisa by experienced psychiatrists. It includes 49 items exploring “presence” or “absence” of lifetime spontaneous symptoms of DP organized into four domains: (1) Derealization, (2) Somatopsychic depersonalization, (3) Autopsychic depersonal- ization, and (4) Affective depersonalization. All patients received a neurological and general medicine review as well as a first-level brain imaging examination (CT and/or MRI). We conducted a systematic literature review with the principal scientific databases (PubMed, Embase, PsychInfo) using the key terms “Capgras Syndrome” and “Misidentificaition”.Discussion and Conclusion: To our knowledge in the literature there are no studies that evaluated dissociative spectrum symptoms in CS in BD. Our findings suggest that autopsychic and affective depersonalization are the effective dissociative dimensions when CS or misidentification phenomena occur within type-I BD. Disso- ciation and self-concept clarity were strongly correlated providing evidence that they may form a unitary underlying concept of ‘self- concept integration’. This particular condition of identity and self fragmentation, as well as reduction of self clarity, could be the key to shedding light on the interconnection between affective and nonaffective psychotic disorders from schizophrenia to BD, and may underscore the possible validity of the concept of the unitary psychosis (Einheitpsychose) proposed by Griesinger [3−5]. Fur- ther research is warranted to replicate our clinical and qualitative observations and, in general, quantitative studies in large samples followed up over time are needed. Methodological limitations, clinical implications and suggestions for future research directions are considered.References
[1] Fishbain D.A., 1987. The frequency of Capgras delusions in psychiatric emergency service. Psychopathology 20:42−47.
[2] Salvatore P., Bhuvaneswar C., Tohen M., Khalsa H.M.K., Maggini C., Baldessarini R.J., 2014. Capgras’ Syndrome in first-Episode Psychotic Disorders. Psychopathology 47(4):261−9.[3] Griesinger W., 1882. Mental pathology and therapeutics, in: Griesinger W., Book third, Forms of mental disease, New York, Hafner Pub. Co., p.144–145.
[4] Reininghaus U., Priebe S., Bentall R.P., 2013. Testing the psychopa- tology of psychosis: evidence for a general psychosis dimension. Schizophr Bull 39(4):884−95.
[5] Kumbier E., Herpeterz S.C., 2010. Helmut Rennert’s universal gen- esis of endogenous psychoses: the historical concept and its signif- icance for today’s discussion on unitary psychosis. Psychopathology 43(6):335−44
Duloxetine in panic disorder with somatic gastric pain
Full text linkMatteo Preve,1 Cristiana Nisita,1 Massimo Bellini,2 Liliana Dell'Osso1 1Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, 2Department of Gastroenterology, Gastrointestinal Unit, University of Pisa, Pisa, Italy Abstract: Panic disorder is the most common type of anxiety disorder, and its most common expression is panic attacks characterized with sudden attacks of anxiety with numerous symptoms, including palpitations, tachycardia, tachypnea, nausea, and vertigo: ie, cardiovascular, gastroenterologic, respiratory, and neuro-otologic symptoms. In clinical practice, panic disorder manifests with isolated gastroenteric or cardiovascular symptoms, requiring additional clinical visits after psychiatric intervention. The first-line treatment for anxiety disorders, and in particular for panic disorder, is the selective serotonin reuptake inhibitors. However, these drugs can have adverse effects, including sexual dysfunction, increased bodyweight, and abnormal bleeding, that may be problematic for some patients. Here we report the case of a 29-year-old Caucasian woman affected by panic disorder with agoraphobia who was referred to our clinic for recurrent gastroenteric panic symptoms. The patient reported improvement in her anxiety symptoms and panic attacks while on a selective serotonin reuptake inhibitor, but not in her gastric somatic problems, so the decision was taken to start her on duloxetine, a serotonin-norepinephrine reuptake inhibitor. After 6 months of treatment, the patient achieved complete remission of her gastric and panic-related symptoms, and was able to stop triple gastric therapy. Other authors have hypothesized and confirmed that duloxetine has greater initial noradrenergic effects than venlafaxine and is effective in patients with panic disorder. This case report underscores the possibility of tailoring therapeutic strategies for the gastroenteric expression of panic disorder. Keywords: anxiety disorder, panic attacks, palpitations, tachycardia, tachypnea, nausea, vertig
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
- …
