1,720,971 research outputs found
Intranasal Immunization With 54 kDa Hemagglutinin Pili Protein of Streptococcus pneumoniae Increase Expression of pIgR
No full textAbstract Book The 2nd ICOLIB BIO-UNEJ 2017Streptococcus pneumoniae can cause many infections like meningitis, bacteremia, otitis media and particularly pneumonia in children
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
The Effect of Intranasal Immunization with Streptococcus Pilus Protein on Nasopharyngeal pIgR and IgA Expression in Rats
No full textTurkish Journal of Immunology 2018; 6(3):87−94 (www.turkishimmunology.org)Introduction: Streptococcus pneumoniae (S. pneumoniae) causes pneumococcal disease, which has high mortality and
morbidity in children under two years of age, the elderly and immunocompromised individuals. This disease can be
prevented by immunization, but the current vaccine, pili protein vaccine (PPV), is less likely to protect children under
the age of two and only protects against the serotypes contained in the vaccine. Hence, a new vaccine is needed to enable
full protection. The use of bacterial pili proteins may offer an alternative new vaccine. Therefore, the determination of
the ability of such proteins to stimulate mucosal immunity with indicator expression of pIgR and s-IgA is required.
Materials and Methods: Pili were isolated using the pili bacterial cutter method, and used for nasal vaccination to
the rats. TGF-β1, IL-17A, and s-IgA were measured by ELISA while pIgR was examined by immunohistochemistry.
Results: This study demonstrated that intranasal immunization with antigen (54 kDa pili protein) and antigen plus
adjuvant significantly increased (p<0.05) the expression of TGF-β1. However, the expression of IL-17A increased
significantly (p<0.05) only in rats immunized with antigen plus adjuvant. Further analysis demonstrated that intranasal
immunization with antigen and antigen plus adjuvant significantly increased (p<0.05) expression of pIgR. Expression
of sIgA in nasal lavage significantly increased (p<0.05) in those rats which had been immunized with pili protein plus
adjuvant.
Conclusion: This study showed that the immünization with S. pneumoniae pili protein increased expression of pIgR
and sIgA which are important mucosal immunity components. Therefore, this protein has potency to be developed as
nasal vaccination to prevent S. pneumoniae infection
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
- …
