618 research outputs found
Berta Lule oral history transcript
No full textA transcript of an oral history of Berta Lule, Teacher at W.L.Henry Elementary School, on Hispanics in the Hillsboro schools. The school is in it first year of the dual immersion program which starts in Kindergarten. It is a choice offered by the school. 70% of students are Spanish speaking. Prior to the beginning of the program some students were lost to Forest Grove and Beaverton schools. The school does still continue to have the option of the ESL program. Ms. Lule was born in Mexico, moved to California at age 5, and then to Oregon at age 9. In 2000 was a part of planning strategies to improve Hispanic drop-out rate. Ms. Lule employs GLAD or Guided Language Acquisition Design training techniques. Some of these techniques include visuals, vocabulary, and writing. The author Alma Florado, from San Francisco, brought a reading/writing outreach program for parents and students to the school
SUMO conjugation to spliceosomal proteins is required for efficient pre-mRNA splicing
No full textPre-mRNA splicing is catalyzed by the spliceosome, a multi-megadalton ribonucleoprotein machine. Previous work from our laboratory revealed the splicing factor SRSF1 as a regulator of the SUMO pathway, leading us to explore a connection between this pathway and the splicing machinery. We show here that addition of a recombinant SUMO-protease decreases the efficiency of pre-mRNA splicing in vitro. By mass spectrometry analysis of anti-SUMO immunoprecipitated proteins obtained from purified splicing complexes formed along the splicing reaction, we identified spliceosome-associated SUMO substrates. After corroborating SUMOylation of Prp3 in cultured cells, we defined Lys 289 and Lys 559 as bona fide SUMO attachment sites within this spliceosomal protein. We further demonstrated that a Prp3 SUMOylation-deficient mutant while still capable of interacting with U4/U6 snRNP components, is unable to co-precipitate U2 and U5 snRNA and the spliceosomal proteins U2-SF3a120 and U5-Snu114. This SUMOylation-deficient mutant fails to restore the splicing of different pre-mRNAs to the levels achieved by the wild type protein, when transfected into Prp3-depleted cultured cells. This mutant also shows a diminished recruitment to active spliceosomes, compared to the wild type protein. These findings indicate that SUMO conjugation plays a role during the splicing process and suggest the involvement of Prp3 SUMOylation in U4/U6U5 tri-snRNP formation and/or recruitment.Fil: Pozzi, María Berta. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Bragado, Laureano Fabian Tomas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Will, Cindy L.. Max Planck Institute For Biophysical Chemistry; AlemaniaFil: Mammi, Pablo Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Risso, Guillermo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Urlaub, Henning. Max Planck Institute For Biophysical Chemistry; AlemaniaFil: Lührmann, Reinhard. Max Planck Institute For Biophysical Chemistry; AlemaniaFil: Srebrow, Anabella. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentin
Berta Hees
No full textPhotograph - Berta Hees standing in front of a log cabin that was being restored at a roadside park between Swan Hills and Fort Assiniboine, Albert
Nancy Appleby and Berta Hees
No full textPhotograph - Nancy Appleby and Berta Hees at the river front. Athabasca, Albert
Mrs. Taylor and Berta Hees
No full textPhotograph - Two woman (Mrs. Taylor and Berta Hees) at the cenotaph. Fort Assiniboine, Albert
In Tune, BBC Radio 3: 'Berta Joncus in conversation with Sean Rafferty about her book Kitty Clive, or The Fair Songster'
No full textSean Rafferty presents a lively mix of music and arts news with live performance in the studio from mezzo-soprano Clara Mouriz with Jaume Santonja Espinós. The viol consort Fretwork join us too, and author Berta Joncus chats to Sean about her new book Kitty Clive, or The Fair Songster
Alice B. Donahue and Berta Hees
No full textPhotograph - Alice Donahue and Berta Hees posing with local girls in Hawaii, US
Berta Smit Collection index
No full textThis index describes the Berta Smit Collection and contains articles ; note books ; clippings ; manuscripts ; interviews ; radio talks ; book reviews ; speeches ; personalia.
Berta Smit (1926-1997) was a well-known author for books such as Juffrou Sophia vlug vorentoe, Die man met die kitaar, Die vrou en die bees etc. and literary figure. This collection consists of articles, manuscripts inter alia of 'Juffrou Sophia vlug vorentoe', note books, interviews, radio talks, speeches and book reviews. The collection is compiled into 13 pamphlet boxes
Nancy Appleby, Alice B. Donahue and Berta Hees
No full textPhotograph - Three women (Nancy Appleby, Alice B. Donahue and Berta Hees) on the beach, Hawai
Nancy Appleby, Alberta McDonald, Annie Eherer and Berta Hees
No full textPhotograph - Tea at Anna Eherer's home, Athabasca, Alberta. Left to right: Nancy Appleby, Alberta (Bert) McDonald (Alice's sister), Annie Eherer and Berta Hee
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