187,912 research outputs found
Stem Cells and the Regenerating Heart
No full textThe impediment to adult mammalian cardiac regeneration has been attributed to its distinct embryonic history, and to the relative paucity of progenitor cells residing within the heart. The primitive heart tube, composed of contracting cardiomyocytes lined by a layer of endocardial cells, ensures the establishment of a circulatory system which is critical to support rapid rates of embryonic growth. Actively contracting fetal cardiomyocytes must continue to divide to provide for further growth of the embryonic heart. A recent report shows that the heart possesses regenerating capacities in which stem or precursor cells "refresh" adult mammalian cardiomyocytes after ischemia or pressure overload, but not during aging. Strategies have been proposed to regenerate the heart via cell therapy, combined with tempering the hostile environment of the infarct, by administration of cell survival and antiinflammatory molecules. Important advances in the control of stem cell fate have also moved the field of regenerative medicine closer towards applicable therapies for cardiac muscle regeneration. The field has yet to overcome significant obstacles, including the incomplete cell differentiation of stem cells, the paucity of organ-specific stem cell resources, and the immunogenicity of the transplanted cells. The presence of a circulating cell population that could restore the heart has gained credibility from observations of sex-mismatched cardiac human transplants in which a female heart is transplanted into a male host. Emerging concepts of regeneration as an evolutionary variable are dramatically illustrated by the relatively robust proliferative capacity of the injured heart in other vertebrate species
Supplemental Material - Do Buffer Zone Programs Improve Local Livelihoods and Support Biodiversity Conservation? The Case of Sagarmatha National Park, Nepal
No full textSupplemental Material for Do Buffer Zone Programs Improve Local Livelihoods and Support Biodiversity Conservation? The Case of Sagarmatha National Park, Nepal by Thakur Silwal, Bishnu P. Devkota, Prabin Poudel and Mark Morgan in Tropical Conservation Science</p
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
sj-docx-2-npx-10.1177_1934578X231154965 - Supplemental material for Chemical Characterization of Three <i>Artemisia tridentata</i> Essential Oils and Multivariate Analyses: A Preliminary Investigation
No full textSupplemental material, sj-docx-2-npx-10.1177_1934578X231154965 for Chemical Characterization of Three Artemisia tridentata Essential Oils and Multivariate Analyses: A Preliminary Investigation by Kathy Swor, Prabodh Satyal, Ambika Poudel and William N Setzer in Natural Product Communications</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
sj-pdf-1-ajs-10.1177_03635465231188114 – Supplemental material for Progression of Osteoarthritis at Long-term Follow-up in Patients Treated for Symptomatic Femoroacetabular Impingement With Hip Arthroscopy Compared With Nonsurgically Treated Patients
No full textSupplemental material, sj-pdf-1-ajs-10.1177_03635465231188114 for Progression of Osteoarthritis at Long-term Follow-up in Patients Treated for Symptomatic Femoroacetabular Impingement With Hip Arthroscopy Compared With Nonsurgically Treated Patients by Martin Husen, Devin P. Leland, Heath P. Melugin, Keshav Poudel, Mario Hevesi, Bruce A. Levy and Aaron J. Krych in The American Journal of Sports Medicine</p
sj-docx-1-npx-10.1177_1934578X231225842 - Supplemental material for The Essential Oil of <i>Balsamorhiza sagittata</i> from Southwestern Idaho: Chemical Composition and Enantiomeric Distribution
No full textSupplemental material, sj-docx-1-npx-10.1177_1934578X231225842 for The Essential Oil of Balsamorhiza sagittata from Southwestern Idaho: Chemical Composition and Enantiomeric Distribution by Kathy Swor, Prabodh Satyal, Ambika Poudel and William N. Setzer in Natural Product Communications</p
sj-docx-1-npx-10.1177_1934578X231154965 - Supplemental material for Chemical Characterization of Three <i>Artemisia tridentata</i> Essential Oils and Multivariate Analyses: A Preliminary Investigation
No full textSupplemental material, sj-docx-1-npx-10.1177_1934578X231154965 for Chemical Characterization of Three Artemisia tridentata Essential Oils and Multivariate Analyses: A Preliminary Investigation by Kathy Swor, Prabodh Satyal, Ambika Poudel and William N Setzer in Natural Product Communications</p
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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