3,030 research outputs found
The dynamic field of pharmacoeconomics
Maarten Jacobus Postma is Professor in Pharmacoeconomics at the University of Groningen (The Netherlands), Department of Pharmacy, Unit of PharmacoEpidemiology & PharmacoEconomics. Next to teaching, he coordinates the research of a group of ten PhD students, one postdoctoral researcher and five (annually changing) MSc students. The majority of this research is related to the cost-effectiveness of vaccinations and methodological issues surrounding this (dynamic modeling and discounting), besides other health-economic and pharmacoeconomic topics. He is President of the section Public Health Economics of the European Public Health Association (EUPHA). Furthermore, he is on the Scientific Advisory Board of two worldwide consultancy firms. Finally, he advises the Dutch government on the reimbursement of new drugs and vaccines in two high-impact committees (Health Council and Committee Pharmaceutical Help). Here, Professor Postma speaks to Expert Review of Clinical Pharmacology about the dynamic field of pharmacoeconomics
A decapitated food pyramid
Loonen, M.J.J.E.(2016) Een onthoofde voedselpyramide. In: Hacquebord, L., E. Postma & E. Verheul. Met de Zr.Ms.Zeeland op expeditie naar Jan Mayen: 40-4
The impact of vaccination programmes on public health in the Netherlands: A historical analysis of mortality, morbidity, and costs.
On September 14, 2018, Maarten van Wijhe was promoted at the University of Groningen on his PhD thesis entitled ‘The public health impact of vaccination programmes in the Netherlands. A historical analysis of mortality, morbidity, and costs’. The research was performed at the University of Groningen in collaboration with the National Institute for Public Health and the Environment, under supervision of prof. dr. M.J. Postma and prof. dr. J. Wallinga. This article summarizes the most important findings of this thesis
Updated healthcare cost estimate for drug-related hepatitis C infections in the European Union
sj-docx-1-dst-10.1177_19322968221109841 – Supplemental material for Personalizing the Use of a Intermittently Scanned Continuous Glucose Monitoring (isCGM) Device in Individuals With Type 1 Diabetes: A Cost-Effectiveness Perspective in the Netherlands (FLARE-NL 9)
Supplemental material, sj-docx-1-dst-10.1177_19322968221109841 for Personalizing the Use of a Intermittently Scanned Continuous Glucose Monitoring (isCGM) Device in Individuals With Type 1 Diabetes: A Cost-Effectiveness Perspective in the Netherlands (FLARE-NL 9) by Sajad Emamipour, Peter R. van Dijk, Henk J.G. Bilo, Mireille A. Edens, Onno van der Galiën, Maarten J. Postma, Talitha L. Feenstra and Job F. M. van Boven in Journal of Diabetes Science and Technology</p
The public health impact of vaccination programmes in the Netherlands:A historical analysis of mortality, morbidity, and costs
Vaccination programmes are one of the most important public health development of the 20th century. Yet, how much have they actually impacted mortality, morbidity, and health care expenditure in the Netherlands? We collected and digitized large amounts of historical data on mortality, morbidity and costs. Our data go back to the early 20th century. Using statistical analyses, we looked at ‘what would have happened if vaccination programmes had not been implemented?’ By answering this question and comparing the results with what actually happened, we get an impression of the impact of vaccination programmes. We mainly focussed on the 20th century and on the ‘older’ vaccination programmes: diphtheria, pertussis, tetanus, polio, measles, mumps and rubella. While mortality was already declining before vaccination programmes started, they have certainly further reduced childhood mortality: vaccination programmes have averted between 6- and 12-thousand deaths among those born between 1953 and 1992. Vaccination programmes also greatly reduced the number of disease cases reported, ranging from 50% for rubella to 90% for polio. The total expenditure on programmes increased from €5 million in 1957 to €93 million in 2014, mainly due to new and more expensive vaccines. This is still, however, only a fraction of the total government health care spending. Vaccination programmes have saved and continue to save many lives and avert much suffering. We should however recognise that past performance is not indicative of future (or even current) results. Monitoring the impact of vaccination programmes and highlighting their importance to public health remains paramount
Reconstructing the Effectiveness of Policy Measures to Avoid Next-Wave COVID-19 Infections and Deaths Using a Dynamic Simulation Model:Implications for Health Technology Assessment
Objective: The goal of this study was to dynamically model next-wave scenarios to observe the impact of different lockdown measures on the infection rates (IR) and mortality for two different prototype countries, mimicking the 1st year of the COVID-19 pandemic in Europe.Methods: A dynamic simulation SIRD model was designed to assess the effectiveness of policy measures on four next-wave scenarios, each preceded by two different lockdowns. The four scenarios were (1) no-measures, (2) uniform measures, (3) differential measures based on isolating > 60 years of age group, and (4) differential measures with additional contact reduction measures for the 20-60 years of age group. The dynamic simulation model was prepared for two prototype European countries, Northwestern (NW) and Southern (S) country. Both prototype countries were characterized based on age composition and contact matrix.Results: The results show that the outcomes of the next-wave scenarios depend on number of infections of previous lockdowns. All scenarios reduce the incremental deaths compared with a no-measures scenario. Differential measures show lower number of deaths despite an increase of infections. Additionally, prototype S shows overall more deaths compared with prototype NW due to a higher share of older citizens.Conclusion: This study shows that differential measures are a worthwhile option for controlling the COVID-19 epidemic. This may also be the case in situations where relevant parts of the population have taken up vaccination. Additionally, the effectiveness of interventions strongly depends on the number of previously infected individuals. The results of this study may be useful when planning and forecasting the impact of non-pharmacological interventions and vaccination campaigns.</p
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