1,721,478 research outputs found
Bussole e Portolani
No full textIn questa sezione del libro si alternano alcuni immaginari del mare e del Mediterraneo che come bussole e portolani orientano la navigazione di Ermenautica: da spazio di libertà individuale e al contempo di lotta collettiva e ribellione, a regno delle necropolitiche e del feticismo dei confini; da risorsa strategica della politica e involuzione fascista, a dimensione drammatica e vitale di attraversamenti e di migrazioni, ma anche luogo praticato dalle etnografie militanti
Cerebrospinal fluid samples from patients with various neurological disorders have a transmissible cytotoxic activity with similar properties
No full textWhen inoculated into cell cultures to search for cytopathic viruses, six out of 384 cerebrospinal fluid (CSF) samples from patients with different neurological disorders proved to have a transmissible cytotoxic activity (TCA) not correlated to a conventional infectious agents. Properties shown by a TCA previously detected in the CSF sample of a patient with brain ischemia (Portolani et al., 2005) were shared by each of the newly isolated TCAs. We conclude that independently of the neurological clinical picture shown by the patient, the TCA detected in the CSF samples under study could have the same origin
Portolani e mappe nautiche, nozioni grafiche sull’arte del navigare
No full textLe mappe nautiche costituiscono uno strumento indispensabile per la navigazione, la loro evoluzione riferisce le esperienze maturate nel corso dei secoli, le conoscenze tecnico-scientifiche che hanno condotto alla trasposizione grafica delle nozioni utili ai naviganti, dai primi portolani all’attuale cartografia on-line
Beretti F., Cermelli C., Cenacchi V., Orsi C., Blasi E., Portolani M.
No full textMicroglia activation occurs during brain injury, ischemia and several neurological disorders. Moreover, microglial cells are highly dynamic structures also during the “resting” state in vivo, releasing neurotrophic factors and/or pro- and anti-inflammatory cytokines. Recently, we obtained a transmissible cytotoxic activity (TCA) from the cerebrospinal fluid of a patient with brain ischemia. We demonstrated that this TCA is associated with one or 2 protein(s), that supposedly underwent misfolding, and causes apoptotic cytotoxicity in a variety of cell lines. In this work, we studied microglia response to this TCA. The murine brain macrophage cell line RR4 was stimulated with TCA. Its response was evaluated as phagocytosis and antifungal activity against C. Albicans, and as secretion pattern, measuring MIP-1and TNF- by commercial sandwich ELISAs, nitric oxide (NO) by Griess reaction and phosphorylation of p38 by Fast Activated Cell-based ELISA.Microglia stimulated with TCA showed an increase in phagocytosis of C. albicans. On the contrary, the macrophage capability to kill the ingested fungi was diminished. The analysis of soluble factors secreted by microglial cells in response to TCA demonstrated an increase in MIP-1TNF- NO and an activation of p38 MAP kinase. These results suggest an initial microglia activation induced by TCA leading to an increase in candida ingestion not followed by killing of the fungus. Activation of p38 MAP kinase could suggest the induction of a signaling cascade leading to TCA production which in turn could cause failure in the antifungal activity. Moreover, MIP-1a, NO and TNF-a secretion by microglia cells and induction of apoptosis could provide an in vitro model for the cell events associated with brain ischemia
Des cold warriors institutionnels : l’Information Research Department du Foreign Office britannique et l’Italie
Get PDF“Studio della cartografia di completamento a terra per i Portolani: il porto di Finale Ligure SV”
No full textDa secoli i portolani accompagnano il navigante nell’avvicinamento a terra e nelle manovre in porto, costituendo uno dei pilastri della documentazione nautica. In un’epoca di valorizzazione del turismo nautico e della navigazione da diporto può essere utile interrogarsi sulla possibilità di una integrazione della documentazione nautica da diporto con un completamento a terra per la documentazione dei punti di interesse turistico-culturali e ricettivi, delle infrastrutture di collegamento e in generale di quanto potenzialmente il territorio a ridosso dei porti turistici può offrire al diportista nautic
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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