262,261 research outputs found
La finestra sul cortile segreto della politica: le elezioni primarie per i parlamentari di PD, SEL e M5S
Analisi delle elezioni primarie per la selezione dei candidati alle elezioni parlamentari del 201
Valutare le competenze pragmatiche di apprendenti brasiliani di italiano LS: un confronto con parlanti nativi sull’atto del richiedere
L’articolo si inserisce nel campo della pragmatica interlinguistica e indaga le richieste prodotte da 30 parlanti nativi di italiano e 30 apprendenti brasiliani di italiano con il duplice obiettivo di identificare le principali somiglianze e differenze tra le richieste dei due gruppi e dimostrare che i dati raccolti tramite DCT possono aiutare nella valutazione della competenza pragmatica degli apprendenti. I dati, analizzati seguendo la metodologia del gruppo di ricerca in Pragmática (Inter)linguística, Cross-cultural e Intercultural dell’Università di San Paolo (Brasile), mostrano che entrambi i gruppi sono sensibili alle variabili contestuali, ma esistono differenze soprattutto a livello pragmalinguistico. Inoltre, le analisi hanno permesso di identificare gruppi di apprendenti con diversi gradi di competenza pragmatica che potrebbero essere dovute al contesto di apprendimento della L2
Feline Injection-Site Sarcoma
Feline injection-site sarcoma (FISS) is an aggressive tumor believed to arise from the proliferation of fibroblasts and myofibroblasts in areas of chronic inflammation, particularly at sites of injection. Local recurrence is frequent after surgical excision. Gelatinases (MMP-2 and MMP-9) and their inhibitor (TIMP-2) are endopeptidases pivotal in extracellular matrix remodeling and therefore in tumor invasiveness. The aim of this study was to investigate the immunohistochemical expression of MMP-2, MMP-9, and TIMP-2 in FISS to assess their usefulness as prognostic factors. Size, soft tissue sarcoma (STS) grading system, depth of infiltration, surgical margins, and Ki-67 index were evaluated as additional prognostic markers. Twenty-four cases of primary FISS were classified according to clinical follow-up as nonrecurrent (NR, n = 14; 58.3%) and recurrent (R, n = 10; 41.7%). MMP-2, MMP-9, and TIMP-2 were variably expressed in the FISS examined, confirming their role in tumor invasiveness, yet they did not show significant differences between the R and NR groups. These results could be due to different tumor stages or to the multiple activities of these enzymes, not limited to ECM remodeling. The immunohistochemical expression of these enzymes considered alone does not seem to be useful as a prognostic marker. STS grading system, depth of infiltration, surgical margins, and Ki-67 index did not relate to recurrence. Instead, the size of the tumor, measured after formalin fixation, with an optimal cutoff of 3.75 cm (accuracy = 86%; P < .05), and the mitotic count, with an optimal cutoff of 20 mitoses/10 HPF (accuracy = 80%; P < .05), could be evaluated as useful prognostic markers.</jats:p
Tumour-associated neutrophils (TANs) in canine melano-cytic tumours: quantitative assessment and prognostic significance
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
- …
