1,721,061 research outputs found
The Use of a novel porcine derived acellular dermal matrix (mucoderm) in peri-implant soft tissue augmentation: Preliminary results of a prospective pilot cohort study
Full text linkObjective. Over the years, several techniques have been proposed for soft tissue augmentation around dental implants in order to improve keratinized mucosa width (KMW). Recently, a porcine derived acellular dermal matrix (Mucoderm) has been proposed as autogenous graft substitute in order to avoid palatal harvesting and obtain comparable results to connective tissue grafts, in terms of aesthetics and function. The aim of this study is to present the one-year follow-up results of this matrix in peri-implant soft tissue augmentation procedures. Material and Methods. Twelve patients were enrolled in this pilot prospective study: a dental implant was placed in the upper premolar area and, at implant uncovering after eight weeks, the matrix was inserted. KMW gain was considered as primary outcome variable. Results. After one month from matrix insertion, mean KMW was 7.86±3.22 mm (100%), with no statistically significant intragroup variations (p>0.05). No membrane exposures or wound healing complications occurred during postoperative phase and, after one year, mean KMW was 5.67±2.12 mm (72.13%). Conclusions. The results of the present pilot study indicate that by placing a Mucoderm membrane during implant surgery the keratinized tissue width can be augmented, and the width remains stable for the assessment period of 12 months. Further studies with greater power and longer investigation period are needed to confirm the suggestion for clinical use. Clinical trial registration number is EudraCT number 2018-000147-16
Surgical management of acute retrograde peri-implantitis: a review of current literature
Full text linkAims: Periapical implant lesions, also named apical peri-implantitis or retrograde peri-implantitis, were described since 1992, and are characterized by progressive bone loss at the periapex of the implant. Several case reports have suggested these lesions are possible causes for early implant failure. The aim of this article was to review the Literature to identify current knowledge on surgical management of acute retrograde peri-implantitis.
Methods: The Authors conducted an independent search of the literature, for reports published from 1st January 2008 up to 1st December 2018 in English in several databases: Pubmed, Web of Science, SciVerse, MEDLINE and through The Cochrane Database of Systematic Reviews. Only articles reporting data on the surgical treatment of dental implants affected by retrograde peri-implantitis were included. Articles with unclear or unavailable data or with less than 6 months of follow- up were excluded.
Results: A total of 47 records was identified through database searching. After removal of duplicates, twenty-three studies were selected for title and abstract analysis, with 14 articles considered for detailed screening. Eight studies were included in the present review: four case series and four case reports. A total of 36 dental implants was treated, with follow-up ranging from 6 months to 6 years. Successful resolution of the peri-apical lesion was observed in 34/36 implants (94.5%), with complete radiographic bone fill and
absence of further symptomatology.
Conclusions: Several surgical techniques have been reported for lesions, with proper endodontic evaluation of adjacent teeth. Surgical and chemical debridement of the implant associated with GBR considered the preferred treatment option
Utilizzo di una matrice xenogenica di collagene nell’aumento dei tessuti molli peri-implantari. Use of a xenogenic collagen membrane in peri-implant soft tissue augmentation
No full textOBJECTIVES Over the years, several techniques have been proposed for peri-implant soft tissue augmentation in order to improve keratinized mucosa width (KMW) and gingival thickness (GT). The aim of this study is to present the one year follow-up results of a xenogenic collagen matrix in augmentation procedures. MATERIALS AND METHODS Ten patients were enrolled in this prospective study: one dental implant was placed in the maxilla in the premolar area and, at the time of second stage surgery, the matrix was inserted. KMW and GT were recorded at 1, 3, 6 and 12 months. RESULTS Mean values of KMW and GT were respectively 1.47±0.23 and 1.35±0.32 mm at baseline, while after 1 year mean values of 4.17±1.98 and 4.12±2.12 mm were recorded. CONCLUSIONS According to the results of this work, KMW and GT were significantly augmented, demonstrating the clinical advantages of this new membrane
Valutazione della necessita'di trattamento ortodontico
No full textA sample of students (aged between 11 and 13 years)undrwent an othodontic visit to evaluate how severe their own malocclusion was estimated by themselves;at the same time the prevalence of malocclusions was asswssed.IOTN index was used for the aforesaid evaluation;this index consists of two components:the former is functional(DHC)while the latter is aesthetic(AC).The Authors visited 488 students:51,2% of them were male and 53% were actually or formerly undergoing an orthodontic treatment.The students were asked to compare their smile with a series of photos with malocclusions of varrying degree.Patients'judgements were compared with clinicians'evaluation thus obtaining a real treatment need estimate
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Clinical and volumetric analysis of peri-implant soft tissue augmentation using an acellular dermal matrix: a prospective cohort study
No full textBackground: The role of keratinized mucosa in promoting peri-implant health is controversial, however recent evidence support the use of soft tissue augmentation procedures around dental implants. Soft tissue substitutes have been proposed to replace autogenous connective tissue grafts, therefore the aims of this study are to report clinical and volumetric three-dimensional changes in mucosal thickness (MT) 1 year after treatment with an acellular dermal matrix (ADM). Methods: Soft tissue augmentation was performed at second-stage surgery in the premolar maxillary area with an ADM. MT was assessed prior to implant placement and 1, 6, and 12 months after treatment. Digital linear and volumetric measurements were recorded at baseline and after 1 and 12 months. Furthermore, clinical parameters (Probing Pocket Depths, Bleeding On Probing, Plaque Index) and marginal bone loss were also recorded. Esthetic outcomes of treatment were evaluated objectively using the Pink Esthetic Score and through patient reported outcomes. Results: Twelve patients were enrolled in this prospective study. Post-hoc analysis of the assessments with Tukey's honestly significant difference adjustment revealed that the MT had increased significantly from baseline to 1 month (P < 0.001), 6 months (P < 0.001) and 12 months (P < 0.001), and remained stable between 6 months and 12 months (P > 0.05). Based on the volumetric evaluation, a shrinkage of 23.31% occurred from 1 month to 12 months (P > 0.05). Conclusions: A significant increase in MT was reported after 1 year, with a mean gain of 1.25 mm. Soft tissues were stable, with no statistically significant differences between 6 months and 1 year
The metabolism of zearalenone in subcellular fractions from rabbit and hen hepatocytes and its estrogenic activity in rabbits.
No full textThe in vitro reduction of zearalenone (ZEN) by subcellular fractions from hen and rabbit hepatocytes clearly shows species-specific differences in the cofactor requirements, rate of metabolism and production of metabolites. The presence of NADH as cofactor in the reaction mixtures enhanced only the reducing activity of the microsomal fraction from rabbit hepatocytes, while NADPH enhanced the reducing activities of the cytosolic fraction from rabbit and both the microsomal and cytosolic fractions from hen hepatocytes. Furthermore, we observed that hen hepatocytes metabolize faster and produce beta-zearalenol (ZEL) as the major metabolite, whereas rabbit hepatocytes metabolize ZEN slowly and mainly into alpha-ZEL, the more uterotrophic metabolite. These last findings are closely related to the higher sensitivity to ZEN estrogenic effects observed in rabbits during the toxicity test involving p.o. administration of the mycotoxin to the animals at 3 dosage levels (0.1, 1, 2 mg/kg body wt)
- …
