1,243 research outputs found
Influence of grain boundary misorientations on the mechanical behavior of a near-alpha Ti-6Al-7Nb alloy processed by ECAP
No full textA near-? Ti-6Al-7Nb alloy was processed by equal-channel angular pressing (ECAP) and the features of microstructural transformation were studied using EBSD analysis and transmission electron microscopy. The results show a non-monotonic variation in the density of low-angle and high-angle boundaries of the ?-phase grains with increasing strain during ECAP. The relationship between the misorientations of the grain boundaries and the mechanical properties of the alloy were examined
High-cycle fatigue behavior of an ultrafine-grained Ti-6Al-4V alloy processed by ECAP and extrusion
No full textThe 85th Anniversary of Academician V.V. Alekseev
No full textIn the article dedicated to the 85th anniversary of Doctor of Historical Sciences, Professor and Academician of the Russian Academy of Sciences Veniamin V. Alekseev, the author traces the main milestones of the scientific biography of the prominent historian who is a well-known specialist in the field of national history and the theory of historical process and the founder of the Institute of History and Archaeology of the Ural Branch of the Russian Academy of Sciences. The paper considers the main stages of the formation of the scientist, his scientific, organizational and administrative activities in the field of historical science. The author highlights the scientific results of Academician V.V. Alekseev that made him well known in Russia and abroad, his theoretical and methodological studies and such large blocks of scientific research as the history of Russian modernizations, the phenomenon of Russian regionalism, the history of metallurgy of the Urals and industrial heritage. The article also focuses on the features of the scientific method of V.V. Alekseev and his merits in the formation of the documentary base for historical research
The game space and its attributive characteristic in the novel "The defence" by V.V. Nabokov
No full text© Journal of Language and Literature. The article deals with the analysis of game space and its attributive characteristic in the novel "The Defence" by V.V. Nabokov. The author provides a review of the most interesting and significant works, devoted to the study of game phenomenon in the creative work by V.V. Nabokov. Besides, the meaning of notion "game text" is expanded in the work; there are also made the conclusions about lexical organization of the novel game space (it is a chessboard in this case) and about ways of characterization of this space: 1) direct characterization (through description); 2) indirect characterization (through the comparison with another subject)
The game space and its attributive characteristic in the novel "The defence" by V.V. Nabokov
No full text© Journal of Language and Literature. The article deals with the analysis of game space and its attributive characteristic in the novel "The Defence" by V.V. Nabokov. The author provides a review of the most interesting and significant works, devoted to the study of game phenomenon in the creative work by V.V. Nabokov. Besides, the meaning of notion "game text" is expanded in the work; there are also made the conclusions about lexical organization of the novel game space (it is a chessboard in this case) and about ways of characterization of this space: 1) direct characterization (through description); 2) indirect characterization (through the comparison with another subject)
Trips Of The Orientalist V.V. Barthold To Bukhara And Their Scientific Significance
No full textThis article discusses the trips of Academician V.V. Barthold to Bukhara to get acquainted with medieval monuments of writing, as well as scientific expeditions of Russian orientalists in the late 19th– early 20th centuries. The author analyzes the scientist's attitude to the issue of studying the history of Bukhar
A personality as the focal point of the weltanschauung exploration by V.V. Zen'kovs'ky
No full textУ
статті
показано ключову роль поняття і принципу особистості у становленні та розвиткові системи поглядів В. В. Зенъковського.In the article the author expounds upon the key role of the concept and principle of the personality in the establishment and the development of V.V. Zen 'kovs 'ky 's system of standpoints
High-resolution reconstruction of sea-ice and hydrological conditions in the south-eastern Laptev Sea during the Holocene deduced from microalgae assemblages
No full textThe Laptev Sea constitutes the central part of the wide Siberian shelf and is regarded as a key area for the freshwater and sea-ice balances of the Arctic Ocean. More than a quarter of the total continental freshwater runoff to the Arctic Ocean is discharged into the Laptev Sea, mainly via the Lena River (Gordeev, 2000). Furthermore, the Laptev Sea polynya is a major source area for sea ice, which is transported to the Siberian branch of the Transpolar Drift (e.g., Zakharov, 1996). Therefore, knowledge of the Holocene variability of the Laptev Sea hydrology is essential for understanding Arctic Ocean water circulation in the past.
Our paleoenvironmental reconstructions based on a detailed study on diatom and aquatic palynomorph assemblages and a detailed radiocarbon (AMS 14 C) chronology of sediment cores obtained from the south-eastern Laptev Sea adjacent to the Lena River Delta. Established linkages between hydrographical parameters (e.g., summer surface-water salinity, sea-ice conditions, Polyakova, 2003; Klyuvitkina, Bauch, 2006) and the composition of surface-sediment diatom and aquatic palynomorph assemblages were used to reconstruct environmental conditions under postglacial sea-level rise and climatic changes. Our records give evidences for inundation of the outer Laptev Sea shelf (> 51 m water depth) approximately 11.3 cal. ka. River-proximal environment characterized by avalanche-like precipitation of river-loaded matter (“marginal filter”) under water salinity <9. The time interval 10.7-9.2 cal. ka was marked by enhanced influence of Atlantic Water on the Laptev Sea hydrology. Because a continuously rising sea level resulted in the southward retreating coastline, surface-water salinities on the outer shelf approached modern values of about 15-16 around 8.6 cal. ka. Approximately 8.9-8.5 cal. ka, when the sea-level reached the position of the present-day isobaths of about 32-30 m, the inner-shelf was flooded. On the inner Laptev Sea shelf, modern-like environmental conditions were reached about 1 to 1.5 ky later, around 7.4 cal. ka. During the last 6 cal.ka in the area adjacent to the Lena Delta variations in surface water salinities, reconstructed using freshwater diatoms as a proxy (Polyakova, 2003) indicate the changes in the volume of the Lena River runoff through the major riverine channels Trofimovskaya, Bykovskaya and Tumatskaya. It was shown, that the Lena River outflow increased in north-eastward direction via Trofimovskaya and Bykovskaya channels 4.2-2.7 cal. ka. A general increasing trend in riverine discharge is observed between 2.7 and 1.2 cal. ka, and a steep decrease in outflow recorded for the last 1.2 cal. ka.
References
Gordeev V.V., 2000. River input of water, sediment, major ions, nutrients and trace metals from Russian territory to the Arctic Ocean. In: E.L.Lewis et al. (eds.) The freshwater budget of the Arctic Ocean, Kluwer, Amsterdam, 297-322.
Klyuvitkina T.S., Bauch H.A., 2006. Holocene changes in paleohydrological conditions in the Laptev Sea based on aquatic palynomorph assemblages. Oceanology, 6, 911-921.
Polyakova, Ye.I., 2003. Diatom assemblages in the surface sediments of the Kara Sea (Siberian Arctic) and their relationship to oceanological conditions. In: Stein, R., Fahl, K, Fütterer, D. K., Galimov, E. M., Stepanets, O. V. (Eds.), Siberian River Run-off in the Kara Sea: Characterization, Quantification, Variability, and Environmental Significance, Proceedings in Marine Sciences, Elsevier, Amsterdam, 375-399.
Zakharov, V. F., 1996. Sea Ice in the Climatic system, St.-Petersburg, Gidrometeoizdat, 213 pp. (In Russian)
Dry eye disease in keratoconus: etiology and medical treatment
No full text
V.V. Averich
Scientific Research Institute of Eye Diseases, Moscow, Russian Federation
This paper reviews published data on the studies on keratoconus associated with dry eye disease (DED) presentations. Despite the lack of a direct correlation between DED and keratoconus, many studies have demonstrated that keratoconus is associated with DED in more than 80% of cases. The author describes major endogenous and exogenous (inflammatory, immune/allergic, mechanical, neuropathic) factors triggering the development and association of these conditions. Approaches to the medical treatment of disorders resulting from the association of these entities are discussed. The primary management strategy implies tear film and ocular surface protection with tear substitutes based on the sodium salt of hyaluronic acid. In the lack of the effect of tear substitutes or in rigid gas permeable contact lens wearers, gel-based dexpanthenol in high concentrations is recommended. This treatment significantly increases drug bioavailability and prolongs the ocular surface reparation. Scleral contact lenses ensuring intact corneal epithelium and high visual acuity in irregular astigmatism caused by keratoconus are also used for corneal protection and DED therapy.
Keywords: keratoconus, keratectasia, dry eye disease, epitheliopathy, tear film.
For citation: Averich V.V. Dry eye disease in keratoconus: etiology and medical treatment. Russian Journal of Clinical Ophthalmology. 2022;22(2):122–126 (in Russ.). DOI: 10.32364/2311-7729-2022-22-2-122-126.
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