1,720,958 research outputs found
Effect of pimobendan on left atrial function: an echocardiographic pilot study in 11 healthy cats
Objectives: – To evaluate the effect of a single dose of pimobendan on left atrial (LA) function in healthy cats. Animals: – Eleven client owned healthy cats. Material and methods: – Standardized and repeated echocardiographic examinations were performed on healthy and conscious cats before and after a single dose of orally administered pimobendan (1.25 mg/cat). Left atrial systolic functional parameters were assessed. Results: – Some of the tested parameters of LA function showed significant improvement after pimobendan administration, whereas no significant effect on left ventricular function was observed. In particular, LA minimal diameters obtained from M-mode images in short (p=0.018) and long (p=0.009) axis reduced after pimobendan administration, whereas LA fractional shortening from short (p=0.027) and long (p=0.042) axis and LA appendage emptying velocity (p<0.001) significantly increased. A mild increase in heart rate (p=0.001), and a transient increase on the peak systolic wave pulmonary vein velocity (p=0.008) were also recorded as a possible effect. Conclusions: – A single dose of pimobendan appears to impact LA function in healthy cats. However, because of the small number of cats included, and the absence of a placebo group, these results cannot be definitively separated from the effect of time. Additional studies are needed to understand if similar effects are observed in cats with cardiomyopathy and LA dilatation
Effects of multi-strains yeast supplementation on health and performances in male Holstein calves
Introduction. Use of antibiotics in livestock production has become a sensitive issue due to the reported cases of antibiotic resistance to pathogens in humans [1]. A correct and specific diet in beef cattle breeding cycle plays a key role to grant a better health and welfare of the animals [2]. The use of yeasts (Saccharomyces cerevisiae, in particular) in the diet of livestock animals, it is now a well-established practice [3, 4] and the positive effects obtained are known [5].
Animals, materials and methods. The objective of this study was to evaluate the health and the performances of young male dairy calves (17±3d) after S. cerevisiae and C. jadinii fractions product supplementation. At a commercial farm, 158 veal calves were enrolled and divided in two groups balanced for live weight: a control group (CTR) 57 animals (no supplementation) and a treated one (TRT) 101 animals (multi-strains yeast supplementation). Both groups were fed with a mixture of milk replacer (chemical composition %: CP 19, EE 17, ash 8) from 400 to 2600g/h/d in 4-16L/h/d, and grain mix with chopped straw (chemical composition %: CP 13.5, EE 3.2, CF 8.2, ash 4.1, DM 88) from 100 to 3500g/h/d. For TRT multi-strains yeast was added in the milk replacer: 5g/h/d during the first 30d, then 3g/h/d until d90. The diet was the same for both groups from d90 to 190 (slaughter). For all animals, mortality, morbidity (veterinary treatments) and individual carcass weights were collected. Blood parameters (Hg, RDW, MCV; d30, 73, 115, 150) and electrophoresis for blood protein characterization (d47, 118) were analysed in 23 randomly selected animals (12 CTR and 11 TRT). On sampled animals, body weights were measured (d0, 47, 82). All data were subjected to AOV procedure then T-test when significant differences were detected.
Results and discussion. Health of calves was improved, but no difference was observed in mortality. Morbidity was reduced from 56% in CTR to 38% in TRT (P<.05), with a reduction of number of chronic animals (≥2 treatments per animal) by 50% (P<.05, table 1). Numerically, the reduction of veterinary treatments was mainly due to reduction of enteric treatments in TRT (-26%). Sampled animals’ ADG was impacted. ADG in TRT was 263g/d and 321g/d higher than in CRT (P<.01) from d0 to 47 and 47 to 82 respectively. Total carcass weight was numerically higher in TRT (+3.4%) than in CTR. Content of total proteins was higher in TRT (P<.01), with higher percentage of γ-globulins (P<.01) and higher percentage of α1-globulins (P<.01). These analyses are in favour of a better activated immune system of veal calves in TRT. No differences were observed on RDW and MCV. No differences in Hg average concentration, but more homogeneity in TRT.
Table 1. Therapies carried out during the trial.
CTR TRT P
% healthy calves (0 treatment) 43.9b 63.4a <.05
% animals treated once 26.3a 21.8a
% animals treated twice or more (chronic) 29.8a 14.9b
Conclusion. This study demonstrates that the addition of multi-strains yeast supplement in the milk replacer during the first 90d of the lifecycle improved the health of veal calves. These results are in line with reduction in use of antimicrobial treatments in farms.
References: [1] Langford et al. (2003) J. Dairy Sci. 86:3963-3966; [2] Heinrichs et al. (2011) J. Dairy Sci. 94:336-341; [3] Alugongo et al. (2017) J. Dairy Sci. 100:1189-1199; [4] Xiao et al. (2019) Animals. 9:4; [5] Robinson et al. (2009) Anim. Feed Sci. Technol. 149:185-98
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Assessment of the impact on human health of the presence of norovirus in bivalve molluscs: What data do we miss?
In the latest One Health ECDC EFSA technical report, Norovirus in fish and fishery products have been listed as the agent/food pair causing the highest number of strong-evidence outbreaks in the EU in 2019. This review aims to identify data gaps that must be filled in order to increase knowledge on Norovirus in bivalve molluscs, perform a risk assessment and rank the key mitigation strategies for this biological hazard, which is relevant to public health. Virologic determinations are not included in any of the food safety and process hygiene microbiologic criteria reflected in the current European regulations. In addition, the Escherichia coli-based indices of acceptable faecal contamination for primary production, as well as the food safety criteria, do not appear sufficient to indicate the extent of Norovirus contamination. The qualitative risk assessment data collected in this review suggests that bivalve molluscs present a high risk to human health for Norovirus only when consumed raw or when insufficiently cooked. On the contrary, the risk can be considered negligible when they are cooked at a high temperature, while information is still scarce for non-thermal treatments
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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