263,510 research outputs found
Nikolaos Politis: Study on the life of modern Greeks
No full textTitle: Μελέτη ἐπί τοῦ βίου τῶν νεοτέρων Ἑλλήνων (Study on the life of modern Greeks) Originally published: in Τόμος Α’ (vol. I), ‘Νεοελληνική Μυθολογία’ of the four-volume Μελέτη ἐπί τοῦ βίου τῶν νεοτέρων Ἑλλήνων (Athens: τύποις Σαραντάκος Οἰκονόμου, 1871). Language: Greek The excerpts used are from the original, Preface, pp. α’- γ.’ About the author Nikolaos Politis [1852, Kalamata..
Modelamiento de los parámetros ambientales de la distribución de Goya-Malabrigo mediante Maxent
No full textEn este capítulo se explora la aplicación del programa MaxEnt, usando como input los sitios asignados a la entidad arqueológica Goya-Malabrigo, con dos objetivos principales: a) precisar objetivamente los parámetros ambientales asociados a la distribución geográfica (el climatic envelope niche, Post 2013) de esta entidad arqueológica y b) estimar el área mas apta para la distribución de esta entidad en base a dichos parámetros ambientales. Tambien se aborda con el pregrama MaxEnt la distribución de los sitios guaraníes del NEA con el objetivo de compararla con el área apta de ocupación de Goya-Malabrigo.Fil: Politis, Gustavo Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Investigaciones Arqueológicas y Paleontológicas del Cuaternario Pampeano. Universidad Nacional del Centro de la Provincia de Buenos Aires. Investigaciones Arqueológicas y Paleontológicas del Cuaternario Pampeano; ArgentinaFil: Domic, Alejandra I.. State University of Pennsylvania; Estados UnidosFil: Bonomo, Mariano. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Arqueología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Capriles, José M,. State University of Pennsylvania; Estados Unido
The effect of calcium on mammary epithelial cell proliferation and the plasminogen activating system
No full textThe objectives of this study were to examine 1) the effect of extracellular calcium on proliferation of bovine mammary epithelial cells, 2) whether extracellular calcium regulates the mitogenic effect of insulin-like growth factor (IGF-I) and epidermal growth factor (EGF) towards mammary epithelial cells, and 3) whether the effects of calcium on growth are mediated through changes in the plasminogen activating system. The BME-UV1 cells were used as a model system. Results showed that optimal proliferation of BME-UV1 cells grown in the presence of 10% dialyzed FBCS was achieved when the culture medium was supplemented with 1-2 mmol L-1 of extracellular Ca2+. IGF-I (P<0.01) but not EGF, increased proliferation of BME-UV1 cells. Furthermore, calcium does not regulate IGF-I and EGF responsiveness of BME-UV1 cells. Northern blot analysis was performed to examine the effect of extracellular calcium on expression of urokinase-type plasminogen activator (u-PA), PA inhibitor 1 (PAI-1) and u-PA receptor (u-PAR) genes by BME-UV1 cells in culture. Results showed that calcium increased expression of all above-mentioned genes after 24 h of exposure of cells to calcium, at a time that the effect of calcium on growth was not apparent. Calcium had no effect on u-PA and u-PAR expression after 48 and 72 h of exposure of cells to calcium, at a time that the effect of calcium on growth was predominant. Calcium caused a small increase of PAI-1 expression after 48 and 72 h but this small increase is apparently of limited biological value
Effect of Vitamin E Supplementation on Various Functional Properties of Macrophages and Neutrophils Obtained from Weaned Piglets
No full textSixteen piglets were used to determine the effect of vitamin E supplementation on several functional properties of macrophages and neutrophils obtained from weaned piglets. Piglets, immediately following weaning, were assigned to one of three experimental groups: control (no vitamin E supplementation), low level of vitamin E supplementation (100 mg DL-α-tocopheryl acetate/kg diet) and high level of vitamin E supplementation (300 mg DL-α-tocopheryl acetate/kg diet). Supplementation of vitamin E lasted for a period of 36 days, following a 3-day adaptation period after weaning. Blood samples were collected on days 0, 12, 24 and 36 of the experimental period, monocytes/macrophages and neutrophils were isolated and the following parameters were determined in macrophages and neutrophils activated by phorbol myristate acetate: total cell-associated and membrane-bound urokinase plasminogen activator (u-PA) activity and Superoxide anion production. Results showed that macrophages and neutrophils isolated from piglets that received supplemental vitamin E had higher (P 0.05) on total and membrane-bound u-PA activities and superoxide anion production by porcine macrophages and neutrophils on days 24 and 36 of the experimental period. In conclusion, the low level of vitamin E supplementation is recommended for piglets for the first 2 weeks after weaning
Oxidative stress in periparturient dairy cows and its relationship with negative energy balance markers
No full textLiving organism’s defensive systems are very sensitive and complex mechanisms. Endogenous production of reactive oxygen species (ROS) is one of the main way these systems can achieve their goals. On the other side, ROS can be dangerous also for the living cells and the right balance between pro-oxidant and antioxidant is essential to avoid oxidative stress. Peripartum is typically a very stressful period of life in producing animals and dairy cows can experience a negative redox status at this time. The aim of the trial was to study the relationship between negative energy balance markers such as NEFA and BHBA and oxidative stress in transition dairy cows. Thirty Holstein Friesian dairy cows over 2 commercial farms located in Milan area were involved in the trial. Blood samples were collected at dry-off, at calving and at 30 DIM. ROS and serum antioxidant capacity (SAC) were measured on samples and the Oxidative Stress index (OSi) was calculated. On the same samples NEFA, BHBA and α-tocopherol concentrations were determined. Statistical analysis was performed with MIXED and CORR procedures of SAS. NEFA and BHBA increased around parturition compared with dry off levels (P < 0.05). At 30 DIM, NEFA decreased to concentrations similar to pre-partum, BHBA concentration instead remained high. α-tocopherol blood levels decreased at calving and increased at 30 DIM at higher values than dry-off (3.12 vs.. 3.59 μg/mL, P < 0.05). ROS results were not significant over the time and SAC values showed a tendency (P = 0.05) to have lower concentration at calving compared with dry-off. OSi results were significantly higher at calving compared with pre-calving (0.167 vs.. 0.214, P < 0.05) and 30 DIM indexes (0.214 vs.. 0.178, P < 0.05). There was a positive correla-tion between NEFA (0.44, P < 0.05) and BHBA (0.28, P < 0.05) serum levels and OSi. The results observed, consolidate the goodness of OSi in detecting oxidative stress in transition cows
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Response of dairy ewes in late lactation to recombinant bovine somatotropin
No full textThis study was conducted to evaluate the effect of recombinant bovine somatotropin (rbST) administration to dairy ewes in late lactation on milk yield, composition, clotting parameters, and plasmin/plasminogen system. Eighty multiparous lactating Comisana ewes (186±18 days in lactation) were randomly assigned to one of two treatments: control and rbST. Slow-release rbST (120 mg/ewe) was administered for two injection cycles of 21 days each. Recombinant bovine somatotropin treatment increased milk (589.7 vs. 483.7 g/d; p < 0.01), protein (35.5 vs. 31.4 g/d; p < 0.05) and lactose (27.3 vs. 23.1 g/d; p < 0.05) yields. The percentage of milk fat (8.2% vs. 8.9%; p < 0.01) and protein (6.0% vs. 6.2%; p < 0.05) decreased, while somatic cells count and pH were unaffected by rbST treatment. Administration of rbST decreased milk coagulation time (r) (12 vs. 13.1 min; p < 0.05), while firming rate (k20) and curd firmness (a30) were unaffected. Plasminogen activity of milk was lower in rbST-treated ewes (18.11 vs. 21.89 U/ml; p < 0.01)
Extrapolation de distribution de sous-échantillonnage dans les cas I. I. D. et "fortement mélangeants"
No full textSérie des documents de travail du CORELA et de HEDM ; 9604 Diffusion du document : INRA Station d'Economie et Sociologie rurales, 65 boulevard de Brandebourg, 94205 Ivry Cedex (FRA) Cote de localisation : PAR. BRT. 1996/P0663 96-04Dans les travaux de D. N. Politis et J. P. Romano, une méthodologie générale de sous-échantillonnage a été proposée pour la construction de régions de confiance asymptotique pour un paramètre thêta thêta (P) inconnu sous des conditions minimales. Néanmoins, dans quelques cas spécifiques, par exemple le cas i. i. d., il a été remarqué que les estimateurs de distribution de sous-échantillonnage étaient sous-efficaces par rapport à des estimateurs alternatifs tels que le bootstrap et/ou la distribution normale asymptotique (avec variance estimée). Les auteurs évaluent jusqu'à quel point des distributions de sous-échantillonnage peuvent être améliorées par la technique d'extrapolation, tout en assurant le maintien de la propriété de robustesse et de consistance de la distribution, même dans les cas non-réguliers. Les cas d'observations i. i. d. et/ou fortement mélangeants sont étudiés
Extrapolation de distribution de sous-échantillonnage dans les cas I. I. D. et "fortement mélangeants"
No full textSérie des documents de travail du CORELA et de HEDM ; 9604 Diffusion du document : INRA Station d'Economie et Sociologie rurales, 65 boulevard de Brandebourg, 94205 Ivry Cedex (FRA) Cote de localisation : PAR. BRT. 1996/P0663 96-04Dans les travaux de D. N. Politis et J. P. Romano, une méthodologie générale de sous-échantillonnage a été proposée pour la construction de régions de confiance asymptotique pour un paramètre thêta thêta (P) inconnu sous des conditions minimales. Néanmoins, dans quelques cas spécifiques, par exemple le cas i. i. d., il a été remarqué que les estimateurs de distribution de sous-échantillonnage étaient sous-efficaces par rapport à des estimateurs alternatifs tels que le bootstrap et/ou la distribution normale asymptotique (avec variance estimée). Les auteurs évaluent jusqu'à quel point des distributions de sous-échantillonnage peuvent être améliorées par la technique d'extrapolation, tout en assurant le maintien de la propriété de robustesse et de consistance de la distribution, même dans les cas non-réguliers. Les cas d'observations i. i. d. et/ou fortement mélangeants sont étudiés
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