1,721,140 research outputs found

    POH-N probe structure.

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    <p>Under normoxic conditions, POH-N is immediately degraded via VHL-mediated ODD, and the resultant POH-N fragments diffuse from the cells. In contrast, POH-N is more stable in HIF-1-active cells, thus creating a contrast between HIF-1-active and HIF-1-inactive cells.</p

    Customizing biometric authentication systems via discriminative score calibration.

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    There is mounting evidence about the benefit of tailoring a biometric authentication system to each user by postprocessing the system output at the score level, also known as client-specific score normalisation. Examples of these procedures are Z-norm and F-norm. These procedures can calibrate the uneven hypothesis space such that the dispropotionate false acceptance and false rejection errors are reduced after the calibration. The interest in studying these schemes is that they are applicable to any biometric authentication system regardless of the underlying biometric modality, and furthermore, potentially be extended to object recognition framed as a verification problem. We propose to further improve these procedures by adding additional client-specific terms that cannot be incorporated easily in their respective existing form. Experiments carried out on 13 face and speech systems show that both variants systematically outperform their respective score normalisation scheme (Z-norm or F-norm)

    No clear visualization of HIF-1-active regions in the permanent brain ischemia model or with delayed injection of POH-N in the focal brain ischemia model.

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    <p>(A) Representative <i>in vivo</i> fluorescence images visualized through a cranial window before and at 5 min, 1 h, and 6 h after POH-N administration are shown. POH-N was injected intravenously at 60 min after permanent MCA occlusion. (B) Representative <i>in vivo</i> fluorescence images visualized through a cranial window before and at 5 min, 1 h, and 6 h following POH-N administration at 24 h after reperfusion. Magnified head images are shown in the lower left panels.</p

    A Bayesian Approach for Modeling Sensor Influence on Quality, Liveness and Match Score Values in Fingerprint Verification

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    Recently a number of studies in fingerprint verification have combined match scores with quality and liveness measures in order to thwart spoof attacks. However, these approaches do not explicitly account for the influence of the sensor on these variables. In this work, we propose a graphical model that accounts for the impact of the sensor on match scores, quality and liveness measures. The proposed graphical model is implemented using a Gaussian Mixture Model based Bayesian classifier. Effectiveness of the proposed model has been assessed on the LivDet11 fingerprint database using Biometrika and Italdata sensor

    Immunohistochemical detection of HIF-1-active cells and POH-N probe.

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    <p>(A) Immunohistochemical analysis of HIF-1α, POH-N (ODD) and HaloTag (green), with or without DAPI nuclear staining (blue), at 1 day after probe administration. Panels at the bottom show magnified images. (B) Similar distributions of HIF-1α, HaloTag, and HSP70 in pyramidal neurons of the cortical layer bordering the infarct. Scale bars, 50 μm.</p

    Biometric System Design Under Zero and Non-zero-effort Attacks

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    An increasing number of studies have reported that the quality of biometric samples has a significant impact on the performance of the system. However, to our best knowledge, these studies are limited to impersonation attempts from dif-ferent subjects, i.e., zero-effort attack, and they do not take into account the possibility of spoof attack, also called non-zero effort attack. In order to thwart the spoof attack, one way is to assess the likelihood of a spoof attempt by using bio-metric liveness measures. Since both biometric sample qual-ity and liveness measures are different, and possibly comple-mentary, we propose an information fusion framework that combines them under both zero- and non-zero effort (spoof) attacks. We implemented this framework using three gener
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