47 research outputs found
Transverse Magnetic Field Effect on Extracellular Fluid Flow along with a Semi-Infinite Vertical Rotating Porous Plate
No full textData on overlapping brain disorders and emerging drug targets in human Dopamine Receptors Interaction Network
No full textIntercommunication of Dopamine Receptors (DRs) with their associate protein partners is crucial to maintain regular brain function in human. Majority of the brain disorders arise due to malfunctioning of such communication process. Hence, contributions of genetic factors, as well as phenotypic indications for various neurological and psychiatric disorders are often attributed as sharing in nature. In our earlier research article entitled “Human Dopamine Receptors Interaction Network (DRIN): a systems biology perspective on topology, stability and functionality of the network” (Podder et al., 2014) [1], we had depicted a holistic interaction map of human Dopamine Receptors. Given emphasis on the topological parameters, we had characterized the functionality along with the vulnerable properties of the network. In support of this, we hereby provide an additional data highlighting the genetic overlapping of various brain disorders in the network. The data indicates the sharing nature of disease genes for various neurological and psychiatric disorders in dopamine receptors connecting protein-protein interactions network. The data also indicates toward an alternative approach to prioritize proteins for overlapping brain disorders as valuable drug targets in the network
The Killing of Avijit Roy: Silencing free-thinking and progressive conscience in Bangladesh
No full text"On February 26 the blogger Avijit Roy, a US-citizen of Bangladeshi origin, published author, and prominent voice against religious intolerance was murdered publicly in Dhaka after returning from a book fair (cf. TheGuardian, 27.2.2015; cf. Alam, 7.2.2015). Roy, an engineer by profession was not only known as a passionate writer but also as the founder of the Bengalilanguage blog Mukto-Mona, the “Free Mind”. (...)
Artists’ Moving Image: South Asian Trajectories
No full textA special South Asia-focused journal edition of the journal, 'Moving Image Review and Art Journal'. The edition includes eight articles, features, reviews and interviews as well as a contextual preface by the editors, Lucia King and Rashmi Sawhney. Trajectories of film history and the practices of 'artists' moving image' makers from South Asia are traced and critiqued, including the significant impact of documentary film experimentation from the 1960s to the present. Author contributors are: Nancy Adajania, Avijit Mukul Kishore, Adnan Madani, Shai Heredia, Nicole Wolf, Kaushik Bhamik, Lucia King and Rashmi Sawhney
New Insights into Schizophrenia Disease Genes Interactome in the Human Brain: Emerging Targets and Therapeutic Implications in the Postgenomics Era
No full textData on overlapping brain disorders and emerging drug targets in human Dopamine Receptors Interaction Network
No full textThe Jamuna-Brahmaputra River, Bangladesh
No full textBangladesh is dominated by three great rivers – the Jamuna-Brahmaputra, Ganga and Meghna – that combine to feed sediment into one of the World’s largest deltas in the Bay of Bengal (Figure 21.1). Bangladesh has been shaped by, and is dependent upon, its rivers, which provide fertile soils and a diverse flora and aquaculture but also bring significant flood hazard and risk to infrastructure for a large and growing population. Current anthropogenic stresses, in terms of changing climate, water diversions, pollution and sediment extraction, are posing new pressures to the river and its inhabitants (Best, 2019). The people of Bangladesh have adapted their lifestyle for centuries to live with river flooding – frequently moving their temporary bankside homes, planting on newly emergent river bars, and sometimes raising their homesteads above water level in flood periods (Paul, 1997). However, a growing population, coupled with the expansion of infrastructure and economic development, has resulted in an increase in the intensity of flood damage (FPCO, 1995; Paul, 1997; CPD, 2004). The lives of many millions of Bangladeshi citizens are reliant on these rivers, with up to 2.3 million people living on the riverine islands alone (Schmuk-Widmann, 2001). Bangladesh’s rural economy relies upon annual ‘normal’ floods to bring moisture and fresh sediments to the floodplain soils (Paul, 1997): for instance, two of the three seasonal rice varieties (aus and aman) cannot survive without floodwater and the fish caught both on the floodplain during flood season and from the many floodplain ponds (‘beels’) provide the main source of protein for many rural populations (Chowdhury, 1994; Paul, 1997; de Graff, 2003; Shankar et al., 2004). However, the effect of ‘abnormal’ floods can be devastating and result in appreciable damage to crops and houses, severe bank erosion with consequent loss of homesteads, schools and land, and loss of human lives, livestock and fisheries (BDER, 2004; Shankar et al., 2004). For example, in the 1998 flood, over 70 % of the land area of Bangladesh was inundated, affecting 31 million people and 1 million homesteads (Chowdhury, 2000). The 1998 flood, which had an unusually long duration from July to September, claimed 918 human lives and was responsible for damaging 16 000 and 6000 km of roads and embankments, respectively, and affecting 6000 km2 of standing crops (Chowdhury, 2000). In the 2004 floods, over 25 % of the population of Bangladesh, or 36 million people, was affected by the floods; 800 lives were lost; 952 000 houses were destroyed and 1.4 million badly damaged; 24 000 educational institutions were affected, including the destruction of 1200 primary schools; 2 million government and private tubewells were affected, and over 3 million latrines were damaged or washed away, this increasing the risks of diarrhoea, cholera and other waterborne diseases. Also, 1.1 million ha of rice crop was submerged and lost before it could be harvested, with 7 % of the yearly aus (early season) rice crop lost; 270 000 ha of grazing land was affected, 5600 livestock perished together with 254 000 poultry and 63 Mt of lost fish production (BDER, 2004; CPD, 2004). In the districts that are dominated by the Brahmaputra-Jamuna River, the 2004 flood damage to infrastructure (homes, roads, culverts), tubewells and latrines, with ensuing unemployment of many of the population, were some of the areas of critical impact. The total cost of the damage caused by the 2004 flood is estimated at $7 billion (CPD, 2004)
Ultrasound guided arthrocentesis in the Emergency Department: A scoping review protocol
No full textTitle:
Ultrasound-guided arthrocentesis in the Emergency Department: A Scoping Review Protocol
Authors:
Avijit Barai1, Sujatha Kamalaksha2, Amy Hogben1, Thedchanamoorthy Prashanth4, and Susie Moreton5
1Consultant, Emergency Department, Epworth Geelong Hospital, Waurn Ponds, VIC 3216.
2Consultant, Department of Rheumatology, Warrnambool Hospital, Warrnambool, VIC 3280.
3Nurse Practitioner Candidate, Emergency Department, Epworth Geelong Hospital, Waurn Ponds, VIC 3216.
4Consultant, Emergency Department, Warrnambool Hospital, Warrnambool, VIC 3280.
5Medical Librarian, Epworth HealthCare, Richmond, VIC
Correspondence to
Avijit Barai: [email protected]
Keywords:
emergency department; arthrocentesis; point of care ultrasound; ultrasonography; joint aspiration
Citation: Barai A, Kamalaksha S, Hogben A, Prashanth T, and Moreton S (2024). Ultrasound guided arthrocentesis in the Emergency Department: A scoping review protocol.
DOI: https://doi.org/10.17605/OSF.IO/487U9
Data Availability: All relevant data are within the paper and its appendix files.
Funding: No author received any funding for this review.
Conflicts of interest: There is no conflict of interest in this project.
Abstract:
Objective: The objective of this scoping review is to describe and explore the breadth and extent of the evidence for ultrasound-guided arthrocentesis (UGA) in the Emergency Department (ED).
Introduction: Joint aspiration or arthrocentesis procedures are commonly performed in the ED for diagnosis and management of painful joints. The integration of ultrasound technology to arthrocentesis has ensured improved patient care and reduced complications.
Inclusion criteria: This scoping review will examine all articles in the English language published between January 2013 and December 2023. We will include human studies in peer reviewed journals and grey literature.
Inclusion criteria:
To define key elements required for our scoping review, including the population, concept, and context (PCC) related to the purpose of the review, we have drawn on guidance within the JBI Manual for Evidence Synthesis (Aromataris and Munn, 2020) when defining our inclusion criteria. Items to be included will meet the following criteria:
1. Population: Adult and paediatric patients who attended ED with joint pain or effusion
2. Concept: The use of ultrasound technology for arthrocentesis.
3. Context: ED.
4. Studies reporting on at least one of the following outcomes:
Clinical indications and feasibility of UGA in the ED.
Procedural success rates of UGA compared to traditional approaches.
Safety outcomes associated with UGA in the ED.
Resource implications of implementing UGA in the ED.
5. Evidence: Peer-reviewed articles including original theoretical or empirical research, randomized controlled trials, non-randomized controlled trials, observational studies, case series, or other quantitative, qualitative, mixed-methods, and experimental research. This will be supplemented by available relevant grey literature.
6. Articles are published in an identifiable academic or scholarly journal while grey articles will be collected from relevant governments and institutions and policymakers;
7. Language: We will include English publications only due to the language fluency of the researchers and lack of funding for language translation.
8. Time-frame 11 years since January 2013. If necessary, we may extend the timeframe to expand search results.
Exclusion criteria:
1. Those studies performed outside ED e.g. in the operating theatre, outpatient clinics, and inpatient wards.
2. Studies where ultrasound was not used for arthrocentesis
3. Secondary articles such as review articles
4. Non-empirical and non-peer-reviewed works, and works situated as opinion-based commentaries, viewpoints, editorials, and perspective pieces, letter to the editor etc.
5. Books, book reviews, and book chapters including government reports, dissertations/theses, conference abstracts, websites, environmental scans, etc.;
6. Studies not reporting on at least one of the specified outcomes
7. Language: Published in a language other than English;
8. Articles published prior to January 1st 2013. This is to ensure that only contemporary literature is considered for analysis.
9. Regarding the inclusion of grey literature, the research team understands the potential to reduce the risk of bias, and acknowledges that including grey literature is usually desired or required for evidence syntheses for highlighting a broader picture of evidence.
Methods: We will apply PRISMA ScR guidelines and Joanna Briggs Institute (JBI) guidelines for this scoping review. A medical librarian will construct a robust and replicable search strategy of contemporary literature in key clinical databases. We will register the protocol in the Open Science Framework (OSF). In addition, we will perform literature review and analysis through rayyan.ai with collaboration of all authors. We will present the qualitative data in charts, tables and figures including the PRISMA ScR flow chart. Two reviewers will perform review independently in a predesigned data charting form, with any discordance to be reviewed by a third investigator.
Conclusion: This scoping review will provide an overview of recent advances in ultrasound-guided arthrocentesis, highlighting their various techniques, efficacy, safety, and potential applications in ED. In addition, it will identify gaps in the literature and highlight areas for future research to improve patient care
Human Dopamine Receptors Interaction Network (DRIN): A systems biology perspective on topology, stability and functionality of the network
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