288 research outputs found
Poem
Title(s): Dad's Army
Charles Jason Lee is the author of The Metaphysics of Mass Art (Mellen, 1999) and Pervasive Perversions (Free Association Books, 2005). His poetry collections include The Day Elvis Died, Polaroid Noise, and God's Potato Peeler. Lee has taught at the universities of Central Lancashire, Essex, East London, and St Martin's College
Methods and applications in computational protein design
Thesis (S.M.)--Massachusetts Institute of Technology, Computation for Design and Optimization Program, 2010.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (p. 107-111).In this thesis, we summarize our work on applications and methods for computational protein design. First, we apply computational protein design to address the problem of degradation in stored proteins. Specifically, we target cysteine, asparagine, glutamine, and methionine amino acid residues to reduce or eliminate a protein's susceptibility to degradation via aggregation, deamidation, and oxidation. We demonstrate this technique on a subset of degradation-prone amino acids in phosphotriesterase, an enzyme that hydrolyzes toxic organophosphates including pesticides and chemical warfare agents. Second, we introduce BroMAP/A*, an exhaustive branch-and- bound search technique with enumeration. We compare performance of BroMAP/A* to DEE/A*, the current standard for conformational search with enumeration in the protein design community. When limited computational resources are available, DEE/A* sometimes fails to find the global minimum energy conformation and/or enumerate the lowest-energy conformations for large designs. Given the same computational resources, we show how BroMAP/A* is able to solve large designs by efficiently dividing the search space into small, solvable subproblems.by Jason Charles Biddle.S.M
A Study of Direct Author Subvention for Publishing Humanities Books at Two Universities: A Report to the Andrew W. Mellon Foundation by Indiana University and University of Michigan
This report was produced as the main deliverable from the Andrew W. Mellon Foundation Grant 41400692, “A Study of Direct Author Subvention for Publishing Humanities Books at Two Universities.” The Indiana University team led by PI Carolyn Walters, consisted of Jason Baird Jackson, Scott Smart, Nick Fitzgerald, Gary Dunham and Shayna Pekala. The University of Michigan team led by PI James Hilton consisted of Paul Courant, Sidonie Smith, Meredith Kahn, Charles Watkinson, Jim Ottaviani, and Aaron McCollough. Lead authorship of the different sections in this report is indicated in the opening paragraphs.This white paper presents recommendations about how a system of monographic publication fully funded by subventions from authors’ parent institutions might function, based on research activities supported by the Andrew W. Mellon Foundation at Indiana University and the University of Michigan. While the contributors present a strong argument for implementing such an “author subvention” system, they describe a number of challenges and potential unintended consequences. Particular issues discussed include how to determine which publishers would be eligible for support, how best to support untenured faculty, and how to avoid disenfranchising scholars at less well-funded institutions.Andrew W. Mellon Foundationhttp://deepblue.lib.umich.edu/bitstream/2027.42/113671/1/IU Michigan White Paper 09-15-2015.pdfDescription of IU Michigan White Paper 09-15-2015.pdf : White pape
The Missing Link: Examining the Supraregional Role of Mleiha in the Realm of the Seleucids Following the Anabasis of Antiochus III.
Ptolemy’s map provides a range of coastal settlements on the Gulf of Oman that have not yet been located with the port of Cryptus being of interest to this dissertation and likely to be located either at Kalba or Dibba al Hisn. Hellenistic material provides evidence for Dibba but as I argue Kalba also would have made a suitable port, although this remains speculative. Further investigations could be directed via the Tell Abraq and Ed Dur sites by considering the likely geography required vis-à-vis adjacent to a sabka and near to mangroves.
There is no extant ancient literature on the Gulf of Oman coast and Mleiha site during the 2nd century BCE. The expedition of Antiochus and the campaign of Numenius
provide the most extensive accounts of Greek interaction with NE Arabia. Antiochus’ interactions with Gerrha provides the point at which Gerrhaen dominance of the region ceases and a site at Mleiha gains prominence. The role of Mleiha is explored in this dissertation as well as considering which of two scenarios unfolds next:
1) Gerrha ceases to hold the Arabian monopoly and an offshoot independent kingdom emerges centred on Mleiha.
2) Seleucid influence is invigorated in the Persian Gulf and Mleiha is sponsored to provide an anchor of power in controlling the flow of trade on the Gulf of Oman
and Persian Gulf coasts.
The seminal evidence now is the Mleiha coin hoard, a succinct understanding of the coinage discovered will undoubtedly lead to a greater depth of understanding on the populace of the 2nd century BCE. It is a pivotal element as coinage is one of the most direct forms of evidence for understanding the economic and political landscape of ancient societies. Beyond this new depth of knowledge will be a further acceptance of the fundamental and integral role of Mleiha as the key component in the supraregional interactions between the Gulf of Oman and wider Indian ocean sphere of exchange operating in conjunction with the Persian Gulf
Contemporary Philosophy on Nature and the Elemental
This year’s symposium will explore and celebrate the thought of one of the leading and most innovative philosophers of our time, John Sallis, who is the Frederick J. Adelmann, S.J. Professor of Philosophy at Boston College. He previously held Chairs at Pennsylvania State University, Vanderbilt University, Loyola University of Chicago, and Duquesne University, where he co-founded the Simon Silverman Phenomenology Center. He is the founding editor of the journal Research in Phenomenology, and General Editor of Studies in Continental Thought for Indiana University Press. He has lectured extensively in Europe, Asia, North and South America and is the author of more than 20 books encompassing the areas of ancient philosophy, German idealism, art, and contemporary philosophy in the phenomenological tradition.
This video (.mp4) is of Session 4: Contemporary Philosophy on Nature and the Elemental.
1:30pm - 5:00pm Session 4: Contemporary Philosophy/On Nature & the Elemental – Africa Room, Student Union
Session Leader: Charles Scott
1. Michael Naas, “Beneath the Earth and in the Heavens: John Sallis in His Elements” - Timestamp: 0:15:00
2. Miguel de Beistegui, “Stretchings of Imagination” - Timestamp: 1:18:42
3. Jason Wirth, Elemental Ecology: Reading John Sallis in an Age of Earth Crisis -Timestamp: 2:30:0
The Saint Charles River project: an exploration of prehistoric trade, exchange and Apishapa architectural patterning in southeastern Colorado
2012 Spring.Includes bibliographical references.The Saint Charles River Project (SCRP) involved the exploration of two rock shelters, and the recordation of five sites that exhibit architectural features near Beulah, Colorado. The construction styles coupled with the physiographic placement of the architectural features along the SCR are indicative of the Apishapa phase (Withers 1954), which occurs between A.D. 1050 - 1450 throughout the greater Arkansas River Basin (ARB). GIS analysis of the geospatial patterning of these sites indicates a significant preference for architectural site selection based on proximity to river access down to the Saint Charles River as well as the view of the surrounding terrain and proximity to water. No evidence was collected during the SCRP supporting the argument of the defensive nature and subsequent placement of these prehistoric architectural features on the landscape. All thermal features recorded are external to the architectural features, which imply a seasonality use, not a year round occupation. This in turn points toward mobility on the landscape that is reinforced by the geochemical evidence of trade or exchange found at the sites reported here. Trade or exchange is demonstrated by the presence of the following exotic materials: Alibates from the Northern Panhandle of Texas, obsidian from Malad, Idaho, obsidian from Northern New Mexico, as well as a Catlinite pipe fragment from Southwestern Minnesota. The sites reported here, help to define the previously unknown western boundary of the Apishapa Phase occupation in Southeastern Colorado, and further help to define the southwestern boundary of trade and exchange throughout the Great Plains during the Late Prehistoric period from A.D. 100 -. 1175
‘ALLOW ME TO INTRODUCE MYSELF — FIRST, NEGATIVELY’: CHARLES DICKENS, ANTHONY TROLLOPE, WILLIAM MAKEPEACE THACKERAY AND FIRST-PERSON JOURNALISM IN THE 1860S FAMILY MAGAZINE
This thesis examines the editorial contributions of W.M. Thackeray, Charles Dickens and Anthony Trollope to the Cornhill Magazine, All the Year Round and Saint Pauls Magazine, analyzing their cultivation of a familiar or personal style of journalism in the context of the 1860s family magazine and its rhetoric of intimacy. Focusing on their first-person journalistic series, it argues that these writers/editors used these contributions as a means of establishing a seemingly intimate and personal relationship with their readers, and considers the various techniques that they used to develop that relationship, including their use of first-person narration, autobiography, the anecdote, dream sequences and memory. It contends that those same contributions questioned and critiqued the depiction of reader-writer relations which they simultaneously propagated, highlighting the distinction between this portrayal and the realities of the industrialized and commercialized world of periodical journalism. It places this within the context of the discourse of family that was integral to the identity of these magazines, demonstrating how these series both held up and complicated the idealized image of Victorian domesticity that was promoted by the mainstream periodical culture of the day, maintaining that this was a standard feature of family magazine journalism and theorizing that this was in fact a large part of its popular appeal to the family market. The introductory chapter examines the discourse of family that dominated the mid-range magazines of the 1860s and how this ties in with the series’ rhetoric of intimacy. Chapter One looks at Thackeray’s ‘Roundabout Papers’, examining the manner in which Thackeray establishes a sense of familiarity between his editorial persona and the reader, only to consistently undermine his own efforts, viewing this within the context of Thackeray’s realist aesthetic. Chapter Two turns to Dickens’s ‘The Uncommercial Traveller’, and traces the relationship between Dickens’s use of the personal, his concept of the ‘Uncommercial’ in the series and his preoccupation with the forces of commercialism and Utilitarianism, which it reads as ultimately concerned with his own sense of complicity in the commercialization of literature. Chapter Three studies ‘An Editor’s Tales’ within the context of its publication during the last months of Trollope’s editorship of Saint Pauls and reads the ambivalent relationship of the series to the personal and its unconventional treatment of the family in relation to this, viewing the series as a part of Trollope’s reaction to the failure of the experiment he undertook with Saint Pauls
A Comprehensive Study of the Trends Occurring in the Industrial Distribution Channel with a Focus on the Distribution of Fluid Power Components
54 p.The author interned with Monnier, Inc. in Algonac, Michigan, a small manufacturer of fluid power air preparation products, and prepared this report on trends in industrial distribution and their impact on small to mid-sized distributors, including Integrated Supply, Consolidation and Consortia, On-line Distribution and Catalog House Distribution.Monnier, Inc. Algonac, Michigan
Making the white man's West: whiteness and the creation of the American West
Includes bibliographical references and index.The West, especially the Intermountain states, ranks among the whitest places in America, but this fact obscures the more complicated history of racial diversity in the region. In Making the White Man's West, author Jason E. Pierce argues that since the time of the Louisiana Purchase, the American West has been a racially contested space. Using a nuanced theory of historical 'whiteness,' he examines why and how Anglo-Americans dominated the region for a 120-year period. In the early nineteenth century, critics like Zebulon Pike and Washington Irving viewed the West as a 'dumping ground' for free Blacks and Native Americans, a place where they could be segregated from the white communities east of the Mississippi River. But as immigrant populations and industrialization took hold in the East, white Americans began to view the West as a 'refuge for real whites.' The West had the most diverse population in the nation with substantial numbers of American Indians, Hispanics, and Asians, but Anglo-Americans could control these mostly disenfranchised peoples and enjoy the privileges of power while celebrating their presence as providing a unique regional character. From this came the belief in a White Man's West, a place ideally suited for 'real' Americans in the face of changing world. The first comprehensive study to examine the construction of white racial identity in the West, Making the White Man's West shows how these two visions of the West--as a racially diverse holding cell and a white refuge--shaped the history of the region and influenced a variety of contemporary social issues in the West today.--Provided by publisher.Introduction: Whiteness and the Making of the American West -- Part I. From Dumping Ground to Refuge: Imagining the White Man's West, 1803-1924 -- "For Its Incorporation into Our Union": The Louisiana Territory and the Conundrum of Western Expansion -- A Climate of Failure or One "Unrivaled, Perhaps, in the World?" -- "The Ablest and Most Valuable Fly Rapidly Westward": Climate, Racial Vigor and the Advancement of the West, 1860-1900 -- Indians not Immigrants: Charles Fletcher Lummis, Frank Bird Linderman and the Complexities of Race and Ethnicity in America -- Part II. Creating and Defending the White Man's West -- The Politics of Whiteness and Western Expansion -- "Our Climate and Soil is Completely Adapted to their Customs": Whiteness, Railroad Promotion and the Settlement of the Great Plains -- Unwelcome Saints: Whiteness, Mormons, and the Limits of Success -- Violence in Defense of the White Man's West -- Conclusion: The Limits and Limitations of Whiteness
Author Entropy vs. File Size in the GNOME Suite of Applications
We present the results of a study in which author entropy was used to characterize author contributions per file. Our analysis reveals three patterns: banding in the data, uneven distribution of data across bands, and file size dependent distributions within bands. Our re- sults suggest that when two authors contribute to a file, large files are more likely to have a dominant author than smaller files
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