1,721,806 research outputs found

    Replication data for Costantino Pischedda and Manuel Vogt, "When Do Religious Organizations Resort to Violence? How Local Conditions Shape the Effects of Transnational Ideology," Ethnopolitics

    No full text
    Replication materials for Costantino Pischedda and Manuel Vogt, "When Do Religious Organizations Resort to Violence? How Local Conditions Shape the Effects of Transnational Ideology," Ethnopolitics (forthcoming

    Appendix for Costantino Pischedda, "Wars within Wars: Why Windows of Opportunity and Vulnerability Cause Inter-rebel Fighting in Internal Conflicts," International Security, Vol. 43, No. 1 (Summer 2018), pp. 138–176, doi:10.1162/isec_a_00322

    No full text
    Appendix for Costantino Pischedda, "Wars within Wars: Why Windows of Opportunity and Vulnerability Cause Inter-rebel Fighting in Internal Conflicts," International Security, Vol. 43, No. 1 (Summer 2018), pp. 138–176, doi:10.1162/isec_a_00322. The appendix contains information on the interview method used for the article and a map of the initial base areas of northern Ethiopia's rebel groups

    Appendix for Costantino Pischedda, "Wars within Wars: Why Windows of Opportunity and Vulnerability Cause Inter-rebel Fighting in Internal Conflicts," International Security, Vol. 43, No. 1 (Summer 2018), pp. 138–176, doi:10.1162/isec_a_00322

    No full text
    Appendix for Costantino Pischedda, "Wars within Wars: Why Windows of Opportunity and Vulnerability Cause Inter-rebel Fighting in Internal Conflicts," International Security, Vol. 43, No. 1 (Summer 2018), pp. 138–176, doi:10.1162/isec_a_00322. The appendix contains information on the interview method used for the article and a map of the initial base areas of northern Ethiopia's rebel groups

    La letteratura incolonnata

    No full text
    Analisi dei critici recensori e dei metodi di recensione letteraria sulle colonne del "Corriere della Sera" nel periodo 1876 - 194

    THE IGLON FAMILY MEMBER NEGR1 PROMOTES NEURONAL ARBORIZATION AND MIGRATION VIA FGFR2

    Full text link
    Negr1 is a member of IgLON adhesion protein family but its functions are largely unknown. In our previous work ((Pischedda et al. 2014), APPENDIX I) we identified Negr1 as a developmentally regulated synaptic protein. Thus we examined the consequences of Negr1 acute down regulation. Strikingly, we found that Negr1 ablation impairs neuronal maturation in vitro. In this project we demonstrated thanks to complementary biochemical and imaging approaches that Negr1 organizes trans-synaptic heterodimer and influences neurites outgrowth via MAPK signaling. In detail, we demonstrated that ectopic Negr1 is sufficient to improve neurite arborization and to rescue the morphological phenotype observed in Negr1 silenced cells. This function is dependent on the activation of MAPK pathway through tyrosine kinase receptors. In fact, we found that Negr1 physically and functionally interacts with FGFR2, modulates FGFR2 response to FGF and consequently influences MAPK pathway. FGFR2 pathway plays an important role during brain development. Not surprisingly, our investigation of the radial migration of newly generated cortical neurons revealed that Negr1- FGFR2 cross-talk controls cortical organization in vivo. Noteworthy, mutations in NEGR1 and FGFR2 genes have been recently identified as ASD candidates. Autism spectrum disorder (ASD) affects 0.9% of children and it is recognized as the most genetic of all developmental neuropsychiatric syndromes. Connectivity dysfunctions have been suggested as causative alterations in ASD. Given the functional, physical and genetic correlation among Negr1 and FGFR2 and the impact of Negr1 on neuron morphology and migration, Negr1-FGFR2 molecular cross talk might arise as a key mechanism during CNS development

    Une inscription phénicienne de la collection Pischedda

    No full text
    Berger Philippe. Une inscription phénicienne de la collection Pischedda. In: Comptes rendus des séances de l'Académie des Inscriptions et Belles-Lettres, 45ᵉ année, N. 5, 1901. pp. 576-579

    Dissenso ed eterodossia nel pensiero ebraico

    Full text link
    La presente raccolta di studi ha cercato di unire studiosi di diversa formazione, il cui intento fosse quello di discutere, attraverso un approccio multidisciplinare e interdisciplinare, i concetti di dissenso ed eterodossia originatisi in seno alla tradizione ebraic
    corecore