1,721,010 research outputs found
Previous pattern of course of the illness as a predictor of response to lithium prophylaxis in bipolar patients
No full textMajor depression with mood-congruent psychotic features: a distinct diagnostic entity or a more severe subtype of depression?
No full textDepressive syndromes and symptoms in subjects with human immunodeficiency virus (HIV) infection
No full textA family study of DSM-III-R schizoaffective disorder, depressive type, compared with schizophrenia and psychotic and nonpsychotic major depression
No full text
Long-term outcome of lithium prophylaxis in patients initially classified as complete responders
No full textLate non-response to lithium prophylaxis in bipolar patients: prevalence and predictors
No full text65 bipolar patients who had shown a complete response to lithium prophylaxis over a 5-year period were followed up for a further period of 5 years. 12.7% of them had at least two affective episodes during the latter period, despite persistently adequate compliance. These late non-responders, as compared with stable responders, had a significantly higher number of previous affective episodes and hospitalizations and a significantly longer duration of illness. It is suggested that the main determinant of late non-response is the 'driving force' of the illness, finally overwhelming the prophylactic effect of lithium
Nonresponse to reinstituted lithium prophylaxis in previously responsive bipolar patients: prevalence and predictors
No full textOBJECTIVE:
The authors explored the prevalence and predictors of nonresponse to reinstituted lithium prophylaxis in bipolar patients who had relapsed after discontinuation of successful lithium treatment.
METHOD:
The study was conducted with 54 bipolar patients for whom lithium had been reintroduced after one or more recurrences following discontinuation of successful prophylaxis. They were followed up, through bimonthly personal interviews, for 1 year after recovery from the episode during which lithium treatment had been resumed, or up to the first recurrence with onset after lithium reinstitution.
RESULTS:
During the follow-up period, 44 patients did not have any affective episodes, whereas 10 had at least one recurrence. The only significant difference between the two patient groups was the longer duration of prediscontinuation lithium treatment for the patients who relapsed.
CONCLUSIONS:
Nonresponse to reinstituted prophylaxis should be considered among the possible risks of the interruption of effective long-term lithium treatment
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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