196,789 research outputs found

    On the motivic class of the classifying stack of G-2$ and the spin groups

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    We compute the class of the classifying stack of the exceptional algebraic group G2 and of the spin groups Spin7 and Spin8 in the Grothendieck ring of stacks, and show that they are equal to the inverse of the class of the corresponding group. Furthermore, we show that the computation of the motivic classes of the stacks BSpinn can be reduced to the computation of the classes of Bn, where n δ Pinn is the "extraspecial 2-group", the preimage of the diagonal matrices under the projection Pinn δ On to the orthogonal group

    Periodic clinical monitoring after liver transplantation

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    During the last two decades, owing to advances in immunosuppressive pharmacotherapy, liver transplantation has been increasingly accepted by the medical community as an effective treatment for patients with end-stage liver disease. Successful transplantation of the liver, however, requires frequent monitoring. Most of the serious infectious complications and allograft dysfunction occur during the early post-transplantation period (i.e., first six months). Blood levels of cyclosporine or tacrolimus, the two major calcineurin inhibitors currently in use, need to be frequently checked. Drug dosage is adjusted in order to maintain target serum concentrations and the patients free of side-effects. In the time, the risk of acute allograft rejection decreases considerably, whereas the proportion of patients with fibrosis or cirrhosis increases, particularly among hepatitis C virus carriers. Graft loss may occur, secondary to recurrent disease or chronic rejection. Patients with well-functioning grafts may still be affected by significant comorbidities, such as hypertension, diabetes, obesity, hyperlipidemia and osteoporosis, which appear to be related to long-term immunosuppression. The incidence of lymphoma, skin and colorectal cancers in liver transplantation recipients exceeds those found in the general population and requires early detection. The principles of the management of medical problems after liver transplantation are a careful clinical assessment of the patient and a judicious use of laboratory tests, radiological evaluation and liver biopsy
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