1,721,019 research outputs found
Skin Biopsies predict acute graft-versus-host disease after small bowel transplantation in pigs
No full textIntestinal transplantation is being increasingly performed to treat patients with irreversible intestinal failure. The major cause of intestinal graft failure is graft-versus-host disease (GVHD) that represents a life-threatening complication after small bowel transplantation (Itx). The purpose of this study was to assess the diagnostic and prognostic value of skin biopsy histological changes for acute GVHD after Itx in pigs. Thirty-four Large White pigs were divided into three groups: Group I with Itx only, Group 2 with Itx and donor bone marrow infusion (Itx BM) and Group 3 (control group-before the operation). Animals received tacrolimus-based immunosuppression from day 0 to day 30 postoperatively. Skin and small bowel biopsies were histologically assessed, analysed and classified from grade I to 4 on postoperative days 15, 30, 45 and 60. There was a strong correlation between the histological grading values of skin biopsy changes and the histological grading values of small bowel biopsy changes (Kendall's tau_b is 0.855 for the Itx group and 0.730 for the Itx BM group). The significant correlation found between skin and small bowel histological changes suggests the prognostic value of skin biopsies after Itx. In conclusion, our findings emphasise the diagnostic and prognostic value of skin biopsy analysis for acute GVHD after Itx
The nurse\u27s role in patient education after liver transplantation
Full text linkUvod: Zdravstvena nega pacientov s presajenimi organi pomeni zagotavljanje specialne zdravstvene nege, usmerjene v zaščito, promocijo in optimizacijo zdravja. Zdravljenje s presaditvijo (transplantacijo) organov je multidisciplinarno in zahteva implementacijo in izvajanje terciarnih znanj in veščin, ki zagotovijo optimalne rezultate zdravljenja: pomembno zmanjšajo skupno število zapletov, pospešijo okrevanje, povečajo varnost in zadovoljstvo pacienta pri njegovi obravnavi in zmanjšujejo stroške zdravljenja. Presaditev jeter je edina učinkovita metoda za zdravljenje akutne in kronične jetrne odpovedi. Namen dela: Prikaz vloge dela medicinske sestre s specialnimi znanji v multidisciplinarnem timu: vloga rabe in izvajanja standardov specialne zdravstvene nege, ki vključujejo etične in konceptualne podlage zdravstvene nege presaditev organov. Specialni standardi zajemajo rabo naprednih znanj z naslednjih področij: prehransko zdravljenje, podpora v zgodnjem in poznem obdobju po presaditvi, spodbujanje k ustrezni telesni vadbi, učenje zgodnje samostojnosti po presaditvi, učenje za samostojno nego, odkrivanje in preprečevanje poslabšanja vedenjskih motenj, psihosocialnih bolezni in dejavnikov okolja, ki bi lahko vplivali na poslabšanje stanja pacienta po presaditvi organa. Metode dela: Uporabili smo deskriptivno metodo dela s pregledom literature slovenskih in tujih podatkovnih baz s področja transplantacije jeter, edukacije pacientov in vpliva pridobljenega znanja na kakovost življenja ter zapletov po presaditvi jeter. Pregledali in analizirali smo strokovno ter znanstveno literaturo v naslednjih bibliografskih bazah: PubMed, Google Učenjak (Scholar), COBISS in ResearchGate. Iskalna strategija je temeljila na rabi naslednjih izrazov: edukacija, presaditev jeter, medicinska sestra, pacient, rehabilitacija, telesna aktivnost, prehrana. Rezultati: Edukacija pacienta ne zajema izključno učenja, ki se nanaša na zdravstveno nego in oskrbo, temveč tudi napotke glede pravilnega prehranjevanja, redne telesne aktivnosti, vnovičnega vključevanja v družbo (družina, prijatelji, služba) in psihosocialna ter zaposlitvena prilagoditev na spremembe po presaditvi jeter. Pri tem je pomemben odnos medicinske sestre do pridobljenega znanja, saj lahko pacient, ki nima vseh potrebnih informacij, živi manj kakovostno življenje. Pri tem je pomembno učenje samodiscipline, ki je ključna pri okrevanju in zmanjšuje tveganje za zaplete. Vloga medicinske sestre v multidisciplinarnem timu je večnivojska. Poskrbeti mora za edukacijo pacienta po presaditvi jeter ter skrbeti za hitro in ustrezno komunikacijo med operaterjem in drugimi sodelavci v timu. Na tak način zagotovi takojšnje in ustrezno ukrepanje v primeru pojava zgodnjih in poznih zapletov po transplantaciji jeter, jih ustrezno zmanjšuje in preprečuje. Zaključek: V prihodnje bi bila smotrna proučitev razvoja aplikacije ali izobraževalnega portala (na primer spletne akademije), v katerih bi imeli zaposleni v zdravstveni negi priložnost svoje znanje kontinuirano nadgrajevati. S tem bi se vsekakor povečala kakovost edukacije in kakovost življenja pacientov po presaditvi jeter v Sloveniji.Introduction: Caring for patients with organ transplants means providing special care aimed at protecting, promoting, and optimizing health. Organ transplant treatment is multidisciplinary and requires the implementation of tertiary knowledge and skills that ensure optimal treatment outcomes: significantly reduce overall complications, speed recovery, increase patient safety, increase patient satisfaction, and reduce treatment costs. Liver transplantation is the only effective method for treating acute and chronic liver failure. Purpose: Demonstration of the role of the work of a nurse with special knowledge in a multidisciplinary team: the role of the use and implementation of special care standards that include the ethical and conceptual basis of organ transplant care. Special standards cover the use of advanced knowledge in the areas of: nutritional treatment in the early and late post-transplant period, promotion of appropriate physical exercise, learning of early independence after transplantation, self-care learning, detection and prevention of aggravation of behavioural disorders, psychosocial diseases and environmental factors. could affect the deterioration of the patient’s condition after organ transplantation. Methods: We used a descriptive method of work with a review of the literature of Slovenian and foreign databases, in the field of liver transplantation, patient education and the impact of acquired knowledge on quality of life and complications after liver transplantation. We reviewed and analyzed the professional and scientific literature in the following bibliographic databases: PubMed, Google Scholar, COBISS and ResearchGate. The search strategy was based on the use of the following terms: education, liver transplant, nurse, patient, rehabilitation, physical activity (PA), nutrition. Results: Patient education does not only require learning regarding care and nursing, but also guidance on proper nutrition (diet), regular physical activity, reintegration into society (family, friends, work) and psychosocial adaptation to changes after liver transplantation and working ability. The attitude of nurse towards acquired knowledge is important, as a patient, who does not have all the necessary information may have a poorer quality of life. It is important for patient to self-care, which is crucial in overall recovery and, above all, taking prescribed drug therapy according to medical plan. The role of the nurse in a multidisciplinary team is multi-level: educating the patient after a liver transplant and taking care of fast and appropriate communication between the operator and other team members. In this way, it provides immediate and appropriate action in the event of early complications after liver transplantation and reduces and prevents them accordingly. Conclusion: Development of an application or educational courses (e.g. online academy) where nurses may have an opportunity to continuously upgrade their knowledge could increase quality of education and patient’s quality of life after liver transplantation in Slovenia
Synthesis of lygands for preparation of chelates
Full text linkV diplomskem delu obravnavam pregled kleščastih ligandov in njihovih kompleksov s kovinami prehoda. Najprej so predstavljene osnovne informacije o kleščastih ligandih in kompleksih. Sledi podroben pregled različnih načinov priprave le-teh. Zatem so opisani štirje različni načini za sintezo kleščastih kompleksov iz kleščastih ligandov in kovin prehoda. Na koncu je opisanih nekaj možnih načinov uporabe kleščastih kompleksov, predvsem pri katalizi kemijskih reakcij ter kot kemijskih senzorjev in stikal.In this thesis, the review of pincer ligands and their complexes with transition metals is presented. At first, there is some basic information about pincer ligands and complexes. Next follows detailed overview of different ways pincer ligands can be prepared. After that, four different ways to synthesize pincer complexes from pincer ligands and transition metals are discussed. Finally, some possible ways of using pincer complexes are described, especially in the catalysis of chemical reactions, and as chemical sensors and switches
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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