3,372 research outputs found
La centralità ritrovata e la legittimazione dei primi Han nei Xinshu di Jia Yi (200-168)
No full textNel 202 a.C. Liu Bang sconfigge Xiang Yu ponendo fine alla guerra civile e si proclama Imperatore della dinastia Han con il nome di Gaozu. I primi decenni del neonato Impero sono un periodo di transizione, caratterizzati da una forte tensione tra il “vecchio” e il “nuovo” sistema politico. Tuttavia, com’è noto, inizialmente gli Han adottano, di fatto, la struttura istituzionale dei Qin, ma ne semplificano alcune regole rituali. Questo momento storico è estremamente importante per la ri-costruzione dello Stato centralizzato sotto l’ègida Han. Con la centralità ritrovata, gli Han devono tuttavia avere il potere legittimato. Secondo la tradizione, i Qin perdono la legittimità per governare a causa di una politica particolarmente dura, e gli Han ascendono al potere garantendo un nuovo ordine e assicurando una nuova stabilità politica e sociale. Quale è l’ideologia alla base della legittimazione politica degli Han? Questo intervento ha come obiettivo l’analisi dell’ideologia, intesa come corpus di idee volte a legittimare la forza politica dominante, come mezzo per l’invenzione dell’Impero Han. L’ideologia è costruita dopo la nascita dell’Impero ed è volta a legittimare il potere acquisito. In particolare si prenderà in esame il ruolo della legge e la depenalizzazione dei reati rivolta all’entourage imperiale. Un testo sarà principale oggetto di analisi, i Xinshu di Jia Yi
Direct replacement of antibodies with molecularly imprinted polymer (MIP) nanoparticles in ELISA - development of a novel assay for vancomycin
No full textA simple and straightforward technique for coating microplate wells with molecularly imprinted polymer nanoparticles (nanoMIPs) to develop ELISA type assays is presented here for the first time. NanoMIPs were synthesized by a solid phase approach with immobilized vancomycin (template) and characterized using Biacore 3000, dynamic light scattering and electron microscopy. Immobilization, blocking and washing conditions were optimized in microplate format. The detection of vancomycin was achieved in competitive binding experiments with a HRP-vancomycin conjugate. The assay was capable of measuring vancomycin in buffer and in blood plasma within the range 0.001-70 nM with a detection limit of 0.0025 nM (2.5 pM). The sensitivity of the assay was three orders of magnitude better than a previously described ELISA based on antibodies. In these experiments nanoMIPs have shown high affinity and minimal interference from blood plasma components. Immobilized nanoMIPs were stored for 1 month at room temperature without any detrimental effects to their binding properties. The high affinity of nanoMIPs and the lack of a requirement for cold chain logistics make them an attractive alternative to traditional antibodies used in ELIS
A tableau calculus for Hajek’s logic BL
No full textWe introduce a tableau calculus for Hajek's Basic Logic BL. This calculus has many of the desirable properties of a proof system: it is cut-free, it has the subformula property. correctness of proof can be checked in P-time, and the number of symbols in any branch of the reduction tree of any sequent Gamma is polynomial in the number of symbols of Gamma. As a corollary we obtain an alternative proof of Co-NP completeness of BL
Optical and electronic properties of monomers of eumelanin: A DFT and TD-DFT computational study
No full textWe report a systematic investigation on the electronic and optical properties of four monomers which are elementary constituents of some of the protomolecules of eumelanin. Eumelanin is the most important form of melanin which is one of the most universal natural pigments in living organisms. For the isolated monomers we performed all-electrons Density Functional Theory (DFT) and Time Dependent DFT (TDDFT) calculations with a localized Gaussian basis-set. For each mo-nomer we determined a series of molecular properties, namely electron affinities, ionization energies, fundamental energy-gaps, optical absorption spectra, and exciton binding energies. We discuss moreover the possible implications of the above electronic and optical properties of the single monomers with respect to the properties of a recently proposed tetrameric protomolecule of eumelanin
Product development kpis: A case study analysis in food and fashion companies
No full textTwo of the main industries that are currently paying huge attention to Product Development (PD) are Food & Fashion (F&F). Even if the remaining supply chain processes (production, distribution, sales) are managed in different ways and dissimilar outsourcing policies are adopted, PD is the most valuable process that both the industries are emphasizing. In the Italian context, F&F also represent two of the three excellences of the Made in Italy (Furniture is the third element), also known as "3F". Therefore, this research constitutes a progress of a previous work, which has examined critical success factors, PD features and PLM functionalities in the two sectors. The aim of this study is to analyse how to control, to monitor and to enhance PD through Key Performance Indicators (KPIs) in F&F companies. From the methodological point of view, case study is adopted as a research strategy, designing two questionnaires with a common structure in order to obtain the required information. Indeed, different companies, belonging to the sectors of interest, have been selected and interviewed. As a result, KPIs are identified and classified. Moreover, a comparison between the previously listed metrics is performed and the drivers affecting similarities and differences are highlighted. This research helps to fill the literature gap, given the few contributions related to product development in the F&F supply chains. It also represents a valuable insight for practitioners who are trying to improve business processes and to increase the control over product development
A complete fuzzy logical system to deal with trust management systems
No full textIn this paper we approach trust management systems in a fuzzy logical setting. The idea is to provide a generalization of the
classical framework, where trust is understood via the dichotomy “true–false”. In order to overcome the classical approach proposed
by Weeks, following the ideas used by Hájek, Esteva, Godo and others to deal with probability, possibility, and necessity in a
many-valued logical setting, we introduce the modal logic
FT n(Ł1/2) built up over the many-valued logic Ł1/2 . In particular,
we enlarge the Ł1/2 language by means of a binary modality says acting on pairs (pi ,) of principals and assertions, where a
principal is a propositional variable and an assertion is a propositional formula of a suited many-valued logic. The idea is to regard the evaluation of the modal formula says(pi , ) as the degree of confidence the principal pi puts in the assertion . For FT n(Ł1/2 ) we introduce a syntax, a semantic and we show completeness. Then we discuss the validity of generalized modus ponens rule in our setting. Finally we deal with a Pavelka-style extension of our logic, and we also extend FT n(Ł1/2 ) to allow principals to be hierarchically organized
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