7,040 research outputs found
IMPLEMENTASI METODE QUALITY CONTROL CIRCLE (QCC) UNTUK MENURUNKAN JUMLAH NG PIN PENDEK PADA MESIN PIN CUTTING DI PT. XYZ
No full textDi dalam perusahaan, terdapat banyak masalah terkait kualitas, sehingga
diperlukan solusi untuk mencapai kualitas yang diharapkan. Salah satu solusinya
adalah dengan menerapkan metode Quality Control Circle (QCC). QCC adalah
sebuah sistem pengendalian kualitas melalui metode 8 langkah dengan sistem
perbaikan berkesinambungan atau kaizen. PT. XYZ merupakan perusahaan
manufaktur otomotif di Indonesia yang berlokasi di Bogor, Jawa Barat. Salah satu
produk dari perusahaan otomotif ini adalah pin diameter 4 mm dan pin diameter 2
mm. Short pin adalah kondisi dimana produk pin yang dihasilkan oleh mesin pin
cutting memiliki dimensi dibawah standar yang sudah ditetapkan. Standar dimensi
pin adalah 9 mm dengan toleransi +0 mm dan -0,15 mm. Efek dari pin pendek ini
adalah dapat mengakibatkan mesin stop pada bagian assy, kerusakan tools dan
membuat efisiensi menurun. Penelitian ini bertujuan untuk Menganalisa kecacatan
produk pin diameter 2 mm, Mengetahui faktor-faktor penyebab kecacatan produk
pin 2 mm dan Memberikan usulan perbaikan untuk mengurangi kecacatan produk
pin 2 mm menggunakan metode Quality Control Circle (QCC). Penelitian ini
menggunakan metode Quality Control Circle (QCC), yang didalamnya terdapat 8
Step for Problem Solving dan 7 Quality Control (QC) Tools. Berdasarkan analisa
kondisi ada yang dilakukan terhadap No Good (NG) Pin pendek menggunakan
faktor 4M+1E adalah dari faktor material dan methode. Dengan menggunakan
bantuan diagram sebab-akibat (fishbone), dapat diketahui akar penyebab terjadinya
NG Pin Pendek adalah tidak adanya periode waktu pembersihan cutting unit,
pengecekan secara visual atau subjektif dan straightening model forming. Usulan
perbaikan yang dilakukan guna mengurangi No Good (NG) Pin pendek yaitu
membuat Jig center Cutting Round Blade Block (CRBB) & Cutiing Round Blade
Slide (CRBS), Menambahkan periode waktu pembersihan di Work instruction (WI)
dan mengganti bentuk straightener dari deformed menjadi roller.
********
Within the company, there are many problems related to quality, so solutions
are needed to achieve the expected quality. One solution is to apply the Quality
Control Circle (QCC) method. QCC is a quality control system using an 8-step
method with a continuous improvement system or kaizen. PT. XYZ is an automotive
manufacturing company in Indonesia located in Bogor, West Java. One of the
products from this automotive company is a 4 mm diameter pin and a 2 mm diameter
pin. Short pin is a condition where the pin product produced by a pin cutting
machine has dimensions below the established standards. The standard pin
dimensions are 9 mm with a tolerance of +0 mm and -0.15 mm. The effect of this
short pin is that it can cause the machine to stop at the assembly, damage tools and
reduce efficiency. This research aims to analyze defects in 2 mm diameter pin
products, find out the factors that cause defects in 2 mm pin products and provide
suggestions for improvements to reduce defects in 2 mm pin products using the
Quality Control Circle (QCC) method. This research uses the Quality Control
Circle (QCC) method, which contains 8 Steps for Problem Solving and 7 Quality
Control (QC) Tools. Based on the condition analysis carried out on the short NG
Pin using factors 4M+1E, namely material and method factors. By using the help
of a cause-and-effect (fishbone) diagram, it can be seen that the root cause of Short
NG Pins is the absence of a time period for cleaning the cutting unit, checking
visually or subjectively and straightening the forming model. Proposed
improvements made to reduce short NG Pins are making the Jig center Cutting Round Blade Block (CRBB) & Cutiing Round Blade Slide (CRBS), adding a
cleaning time period at Work instruction (WI) and changing the shape of the
straightener from deformed to rolle
Si Kenkoy Bilang Kuwelang Ingles sa Komiks: Isang Pagdalumat sa Karabaw English Bilang Instrumento ng Pagsulong ng Makabayang Diwa sa Panahon ng Kolonyalismong Amerikano; 1929-1934
No full textAbstrakAng tinaguriang “Carabao English” ay inilalarawan bilang isang katawa-tawa at hindi kanais-nais na paraan ng komunikasyon. Kinikilala ito bilang paaran ng pilit na paglakip sa dayuhang wika kung saan nagkaroon ng korupsiyon (sariling maka-Pilipinong pagbabaybay) ang wikang Ingles dahil sa naging paghahalo nito sa wikang Filipino. Tatangkain ng papel na ito na matunton ang naging paggamit sa “Carabao English” na mababakas sa mga diyalogo na inilarawan ni Tony Velasquez sa kaniyang likhang-sining na Kenkoy Komiks. Si Kenkoy ang kumatawan sa ‘kuwelang Ingles’ na sa unang pagtingin ay katawa-tawa ngunit kung bibigyan ng malalim na pagsusuri ay nagpapahiwatig ng mga makabayang aral at mga tunggalian sa isang kolonyal na lipunan. Ang layunin ng pag-aaral ay mabigyan ng masusing pagtalakay at masuri ang mga simbolismong pumapaloob sa Kenkoy Komiks na makikita sa ilustrasyon at mga linya nito. Bukod pa rito, layunin ding mabigyang-linaw at maisakonteksto ang nilalaman ng sining ng pagguhit at wikang “Carabao English” sa ilalim ng pamamahala ng Estados Unidos sa Pilipinas at ang papel at paggamit ng nasabing wika sa layunin ng may-akda upang maisulong ang kaniyang mithiing pagkabansa. Matutunghayan mula sa pag-aaral ang pagtugon at ang pakikipagtunggali ng lipunang Pilipino sa panahon ng mga kultural na pagbabago sa dagok ng kolonisasyon mula sa komiks. Iminumungkahi ng pag-aaral na nagkaroon ng proseso ng akulturasyon sa wika kung saan sinasalamin nito ang pag-angkin ng lipunang Pilipino sa mga dayuhang elemento, ngunit nagkaroon ng pagtatakip upang maipagpatuloy ang diwang makabayan sa kabila ng kaayusang kolonyal na pinatatakbo ng Estados Unidos sa bansa. Mga Susing Salita: komiks, Carabao English, Kenkoy, patriotismo, wika Kenkoy’s Humourous English in Comics: An Analysis on the use of “Carabao English” as an Instrument of Advancing Patriotism under the American Colonial Period; 1929 – 1934 Abstract“Carabao English” is portrayed as a farcical and an unfavorable means of communication. It was known to caused by an enforced adherence to the use of a foreign language wherein it formed a ‘corrupted version’ (based on the Philippine enumeration) of the English language due to its contact and mixing with the Filipino language. This paper aims to trace the usage of “Carabao English” based on the dialogues in Tony Velasquez’ Kenkoy Komiks. The main character, Kenkoy, embodies the use of “Humourous English” which at first glance may seem laughable however under thorough analysis implies patriotic values and underscores the struggles of Filipinos under a colonial society. The purpose of this study is to highlight and contextualize the use of “Carabao English” under the American colonial period in the Philippines and its use by the author in order to achieve nationhood. The dynamics of response and conflict within the Filipino society under a period of cultural change brought about by a new colonial era based on the comics, can be seen from the study. The study proposes that language underwent a process of acculturation where it reflects a gradual acceptance of foreign cultural elements within the Filipino society but nevertheless, became instrumental in promoting patriotism by serving as an alternative expression of continued resistance to American colonial rule.Keywords: comics, Carabao English, Kenkoy, patriotism, languag
The Biology and Biochemistry of PhoH2 proteins
No full textPhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside. PhoH2 is a PIN PhoH domain fusion, and these proteins are currently annotated as having unknown function and are described as PhoH like. PhoH domains are thought to be ATPases and all characterised PIN domain proteins are RNases. Most efforts have focussed on determining the role of PIN domain proteins that comprise the toxic component (VapC) of VapBC toxin antitoxin systems, in which the PIN domain is coexpressed as part of an operon with an inhibitor (VapB). In the remaining cases where PIN domain proteins can be found such as PIN PhoH domain fusions, these cases remain unexamined. This thesis describes the biological and biochemical characterisation of the PIN PhoH protein, PhoH2 from Mycobacterium tuberculosis and Mycobacterium smegmatis, along with a preliminary structural characterisation of a thermophilic PhoH2 protein homologue.
The phoH2 gene from both mycobacterial organisms was found to be expressed as part of a long mRNA transcript. Examination of these transcripts revealed possible alternative 5’ start sites out of frame with the phoH2 gene. For protein overexpression, and ‘normal’ growth and colony formation with conditional overexpression, phoH2 from M. tuberculosis required 152 bp of the 5’ sequence directly upstream of the annotated phoH2 gene (annotated here as phoH2alt). PhoH2 proteins: PhoH2alt MTB, PhoH2alt MSMEG and PhoH2MSMEG show ATP/Mg²⁺ dependent, sequence specific RNA unwinding and cleavage. The sequence (A C) (A/U) (A/U) (G/C) U was deduced as a substrate for PhoH2, and PhoH2alt MTB also demonstrated unwinding and cleavage activity on its upstream ~152 base RNA transcript, suggesting a potential autoregulatory mechanism. Structural analysis of a thermophilic PhoH2 protein homologue has provided preliminary crystallographic data which along with electron microscopy suggest a ring like hexameric PhoH2 oligomer
Artemio Aranas: Panukalang Salin sa Filipino ng Isang Sugilanon ni Vicente Rama at ang English Translation Dito ni Rudy Villanueva
No full textABSTRAKAng “Artemio Aranas” ay isang maikling kuwento (sugilanon) sa Sugbuanong Binisaya na inakda ni Vicente Rama, kuwentista, peryodista, at politiko mula Cebu. Isinalin ang “Artemio Aranas” sa Ingles ni Renato Madrid, ang sagisag-panulat ni P. Rodolfo Villanueva, at kasama sa mga salin na inilabas sa isang kalipunan noong 2003. Nakapaloob ang kuwento sa kontekstong historikal ng epidemya ng kolera na tumama rin sa Cebu at ibang bahagi ng Pilipinas noong unang dekada ng siglo 20. Iyan ang tatalakayin sa unang bahagi ng papel. Mapapansin sa naratibo ang tunggalian ng tradisyonal na paniniwala at ng mga “bago” noong konsepto na hatid ng medisinang Kanluranin na dinala ng mga mananakop noong Amerikano. Bukod pa rito ang tunggalian sa pagitan ng nakatatanda at mga kabataan, sa loob ng mga pagbabago sa politika, mga wikang opisyal, at kultura sa kapuluan. Kapansin-pansin din ang pagpaksa ng kuwento sa maling pagpapalaganap ng impormasyon umano ng ilang pahayagan sa Cebu at ang pagmamatigas ng ilang mamamayan ng bayan sa harap ng isang epidemya. Ipinapanukala ng may-akda ang salin sa Filipino ng kuwento upang higit na maipaabot sa mga mambabasa na walang access sa orihinal na Sugbuanong Binisaya o saling Ingles. Babanggitin din ang ilang suliranin at siwang sa pagsasalin, lalo na at may mediasyong isinagawa ang Ingles sa pagsasaling ito.Susing salita: Vicente Rama, salin, kathang pangkasaysayan, kolera ABSTRACT“Artemio Aranas” is a short story or sugilanon in Sugbuanong Binisaya. It was written by Vicente Rama: fictionist, newspaper editor, and politician from Cebu City, Cebu. “Artemio Aranas” was translated into English by essayist-fictionist Renato Madrid (nom de plume of Fr. Rodolfo Villanueva) and was among those rendered into that language in a compilation of Rama’s works released in 2003. The short story was situated during one of the cholera epidemics that hit Cebu in the 1900s. That context will be discussed in the first part of the paper. One can notice in the narrative the tensions between “modern, scientific” knowledge in medicine that were brought by American occupiers and the traditional beliefs being held by the Cebuanos during at that time. There were also tensions between the “older” and “younger” generations that broke out amid the political, cultural, and lingustic changes raveling in the archipelago during those times. “Artemio Aranas” also features the perceived misinformation by some newspapers in Cebu on the epidemic and the bull-headedness of some people in that capital of Cebu province. This author recommends a Filipino translation of “Artemio Aranas” in order to make the story more accessible to readers who do not have a copy, either of the Sugbuanong Binisaya original or of the English translation. The challenges in making this translation will also be mentioned. Keywords: Vicente Rama, translation, historical fiction, choler
Ang Babae sa Pook Pagawaan: Mga Espasyo ng Pag-aangkin sa Piling mga Nobela ni Valeriano Hernandez-Peña
No full textABSTRAKNakatuon ang pag-aaral na ito sa pagsusuri sa pampanitikang representasyon ng babae sa pook pagawaan at ang espasyo ng pag-aangkin sa piling mga nobela ni Valeriano Hernandez-Peña. Kung sinasabing ang panitikan ay representasyon ng isinahirayang ugnayan ng mga indibidwal sa kanilang kondisyon ng pag-iral sa lipunan, paano nabibigyan ng pampanitikang representasyon ang babaeng manggagawa sa mga nobela ni Valeriano Hernandez-Peña? Paanong muling nalikha sa mga akda ang mga karanasan ng kababaihang manggagawa – ang pagsasamantala sa tauhan bilang babae at bilang manggagawa? At sa gitna ng mga ito, paano nabibigyan ng ahensiya ang tauhan para baguhin ang kaniyang kalagayan sa nobela? Naging puwersa ang kababaihang manggagawa na kongkretong nagiging materyal ng manunulat sa pagsasahiraya sa unang mga dekada ng siglo 20. Gamit ang alegorikal na pagbasang sumasaklaw sa hanggahang politikal, panlipunan, at historikal, sinikap na bakatin ang ugnayan ng teksto sa konteksto ng ekonomiya, paggawa, at turing sa kababaihan sa unang dekada ng pananakop ng Amerikano, kung kailan umusbong ang mga nobela. Sa pangkalahatan, bagaman karamihan sa mga nobela ni Hernandez-Peña ay tumatalakay sa pag-ibig at nakakahon sa ideolohiya ng patriyarka, may mga guwang sa teksto na nagsilbing daluyan ng mga resistant na imahen/espasyo ng/para sa babaeng manggagawa. Tinatayang mapupunan ng pag-aaral ang mga puwang na naiwan ng ibang manunulat na pumaksa sa kasarian at gayundin, makapagdaragdag sa mga pananaliksik tungkol sa babaeng manggagawa sa ilalim ng kolonyalismong Amerikano. Mga susing salita: nobelang Tagalog, panunuring pampanitikan, babae, manggagawa, panahon ng Amerikano ABSTRACTThe study analyzes how representations in literature relate the imagined and real lives of individuals in society. Because women workers provided a tangible material for Valeriano Hernandez-Peña in re-imagining American colonialism, the article examines how they were recreated in the novels of the author. How did Hernandez-Peña articulate the experiences of the female character and her oppression as a woman and a worker? In the process, how is the character given agency to transform her condition in the novel? Using an allegorical reading that encompasses the political, social, and historical, the researcher outlined connections and correspondences in the context of economics, labor, and prevailing concepts on women during the period. As a whole, even if Hernandez-Peña produced mostly romantic novels confined to the patriarchal ideology, there are crevices in the text where resistant images/spaces of/for women workers flow. The study contributes to the existing research on women workers during American colonialism as well as to the continuing discourses on gender. Keywords: Tagalog novel, literary criticism, women, workers, American perio
A fast and efficient implementation of qualitatively constrained quantile smoothing splines: Working paper series--05-08
No full textExploiting the sparse structure of the design matrices involved in the Frisch-Newton method, we implement a fast and efficient algorithm to compute qualitatively constrained smoothing and regression splines for quantile regression. In a previous implementation (He and Ng, 1999), the linear program involved was solved using the non-simplex active set algorithm for quantile smoothing spines proposed by Ng (1996). The current implementation uses the Frisch-Newton algorithm described in Koenker and Ng (2005a, 2005b). It is a variant of the interiorpoint algorithm proposed by Portnoy and Koenker (1997) which has been shown to outperform the simplex method in many applications. The current implementation relies on the R package SparseM of Koenker and Ng (2003) which contains a collection of basic linear algebra routines for sparse matrices to exploit the sparse structure of the matrices involved in the linear program to further speed up computation and save memory usage. A small simulation illustrates the superior performance of the new implementation
Adjusted Mean Mg (ng/ml), Ca (ng/ml), or Ca/Mg Levels, PIN, and Prostate Cancer.
No full text∧<p>High-grade cancer vs. (negative-controls: p = 0.01),
(PIN: p<0.01), or (low-grade cancer:
p = 0.09).</p>∧∧<p>High-grade cancer vs. (negative-controls: p<0.01), (PIN: p<0.01),
or (low-grade cancer: p = 0.03).</p><p>*Adjusted for age (continuous), treatment for diabetes (Yes/No),
treatment for CVD (Yes/No), WHR (categorized at quartiles), and race
(white, non-white).</p><p>**High-grade cancer vs. (negative-controls:
p = 0.04), (PIN: p = 0.03), or
(low-grade cancer: p = 0.13).</p><p>***High-grade cancer vs. (negative-controls:
p = 0.01), (PIN: p = 0.05), or
(low-grade cancer: p = 0.05).</p><p>No other differences were significant at p<0.05.Additional adjustment
for family history did not change these results.</p
A Parallel Prefiltering Approach for the Identification of a Biased Sinusoid Signal: Theory and Experiments
No full textThe problem of estimating the amplitude, frequency, and phase of an unknown sinusoidal signal from a noisy-biased measurement is addressed in this paper by a family of parallel prefiltering schemes. The proposed methodology consists in using a pair of linear filters of specified order to generate a suitable number of auxiliary signals that are used to estimate—in an adaptive way—the frequency, the amplitude, and the phase of the sinusoid. Increasing the order of the prefilters improves the noise immunity of the estimator, at the cost of an increase of the computational complexity. Among the whole family of estimators realizable by varying the order of the filters, the simple parallel prefilters of orders 2 C 2 and 3 C 3 are discussed in
detail, being the most attractive from the implementability point of view. The behavior of the two algorithms with respect to bounded external disturbances is characterized by input-to-state stability arguments. Finally, the effectiveness of the proposed technique is shown both by comparative numerical simulations and by a real experiment addressing the estimation of the frequency of the electrical mains from a noisy voltage measurement
An Adaptive-Observer-Based Robust Estimator of Multi-sinusoidal Signals
No full textThis paper presents an adaptive observer-based robust estimation methodology of the amplitudes, frequencies and phases of biased multi-sinusoidal signals in presence of bounded perturbations on the measurement. The parameters of the sinusoidal components are estimated on-line and the update laws are individually controlled by an excitation-based switching logic enabling the update of a parameter only when the measured signal is sufficiently informative. This way doing, the algorithm is able to tackle the problem of over-parametrization (i.e., when the internal model accounts for a number of sinusoids that is larger than the true spectral content) or temporarily fading sinusoidal components. The stability analysis proves the existence of a tuning parameter set for which the estimator's dynamics are input-to-state stable with respect to bounded measurement disturbances. The performance of the proposed estimation approach is evaluated and compared with other existing tools by extensive simulation trials and real-time experiments
CD57 in human natural killer cells and T-lymphocytes
No full textThe CD57 antigen (alternatively HNK-1, LEU-7, or L2) is routinely used to identify terminally differentiated ‘senescent’ cells with reduced proliferative capacity and altered functional properties. In this article, we review current understanding of the attributes of CD57-expressing T-cells and NK cells in both health and disease and discuss how this marker can inform researchers about their likely functions in human blood and tissues in vivo. While CD57 expression on human lymphocytes indicates an inability to proliferate, these cells also display high cytotoxic potential, and CD57pos NK cells exhibit both memory-like features and potent effector functions. Accordingly, frequencies of CD57-expressing cells in blood and tissues have been correlated with clinical prognosis in chronic infections or various cancers and with human aging. Functional modulation of senescent CD57pos T-cells and mature CD57pos NK cells may therefore represent innovative strategies for protection against human immunological aging and/or various chronic diseases
- …
