169,873 research outputs found
Los femicidios y su negación en la jurisprudencia. Estudio de casos en la Provincia de Río Negro
No full textFil: Heim, Daniela. Universidad Nacional de Río Negro. Río Negro, Argentina.Fil: Piccone, María Verónica. Universidad Nacional de Río Negro. Río Negro, Argentina.Pese a las dificultades existentes para construir datos precisos sobre la violencia femicida, se estima que en Argentina mueren anualmente más de 250 mujeres por esta causa. Las crecientes demandas de justicia y respeto de los derechos humanos de las mujeres han contribuido a poner el tema en la agenda pública y existe una legislación específica para hacerle frente. Sin embargo, el femicidio aparece sub-representado en las sentencias sobre muertes violentas de mujeres.
Este trabajo presenta un avance de los resultados parciales de dos investigaciones que buscan aportar datos y reflexiones de cómo se están llevando a cabo los procedimientos judiciales sobre femicidios y por qué esta figura no se utiliza de forma generalizada en la investigación y juicio de los casos (Proyectos UNRN PI 40-C-598 (2017-2020), “Femicidios y femicidios vinculados”, dirigido por Heim y PI 40-C-597 (2017-2020), “La doctrina del control de convencionalidad y su recepción por la Corte Suprema de Justicia de la Nación y los tribunales de Río Negro”, dirigido por Piccone)
Thoracolumbar burst fractures associated with incomplete neurological deficit in patients under the age of 40: Is the posterior approach enough? Surgical treatment and results in a case series of 10 patients with a minimum follow-up of 2 years
No full textIntroduction: Surgical management of thoracolumbar burst fractures is controversial. While the goals of surgical treatment are well accepted (i.e., fracture reduction and stabilization, neural elements decompression, and segmental angular deformity correction), the choice of the best surgical approach (i.e., posterior vs. anterior vs. combined approach) remains controversial. Several studies have debated the advantages of each surgical approach but there is no definitive evidence available to date, particularly in young adult patients. The aim of this study was to assess whether posterior approach alone can be a valid surgical treatment for patient under the age of 40 affected by thoracolumbar burst fractures and incomplete neurological deficits.Material and Methods: A total of 10 consecutive patients affected by thoracolumbar burst fractures associated with incomplete neurological deficits treated at our institution from January 2015 to February 2017 were included in our study. All patients were under the age of 40 at the time of injury and underwent decompression and stabilization using the posterior surgical approach alone. Demographics, clinical, and radiographic parameters were recorded preoperatively, postoperatively and at the latest available follow-up. The minimum follow-up was set at 2 years post-operatively.Results: The mean operative time was 303.6 min (range, 138-486). Average blood loss was 756 mL (range, 440-2100). Nine out of ten patients returned to a normal neurological status after surgery while 1 patient showed some improvement but did not recover completely. Segmental kyphotic deformity improved from a mean of 21.8 degrees before surgery to 14.8 degrees at the time of the last follow-up. The anterior and posterior wall height of the fractured vertebra was restored with an average of 4 mm. The Visual Analogue Scale score reported an improvement from the mean preoperative value of 7.92 to 1.24 at the last follow-up; 8 out of 10 patients resumed physical activity while all of them returned to work.Conclusions: A single posterior surgical approach is an acceptable option in terms of clinical, radiological and functional outcomes at 2 years follow-up in patients under the age of 40 presenting with a thoracolumbar burst fracture and neurological deficit. (C) 2019 Published by Elsevier Ltd
Il caso Contrada e i tormenti dei giudici italiani: sulle prime ricadute interne di una scomoda sentenza della Corte EDU
No full textCon la sentenza commentata, la Corte d’appello di Caltanissetta rigetta l’istanza di revisione proposta da Bruno Contrada riguardo alla sentenza di condanna pronunciata nei propri confronti dalla stessa Corte, divenuta definitiva nel 2007 e ormai interamente scontata, rigettando tra l’altro l’argomento, avanzato dal ricorrente, relativo all’illegittimità della condanna medesima al metro dell’art. 7 CEDU, secondo quanto stabilito dalla Corte di Strasburgo nella sentenza Contrada c. Italia (n. 3), pronunciata lo scorso 14 aprile 2015
Influence of manganese dioxide and manganic ions on the production of two proteins in Arthrobacter sp.
No full textThe production by Arthrobacter sp. of a 30-kDa surface protein and a 25-kDa cytoplasmic protein was increased by the presence of MnO2 in the medium. This high production was also observed in the presence of MnO4- (Mn VII). N-terminal and partial internal sequences of the 30-kDa surface protein have shown no homology with other known proteins. The role of this protein is still unknown, but its highly induced synthesis is possibly related to the binding or the processing of manganic ion by the cells. The 25-kDa cytoplasmic protein has been identified by its N-terminal matching sequence as a superoxide dismutase isoenzyme (Mn-SOD). SOD activity measurements performed on cytoplasmic fractions are related to the protein amounts observed by gel electrophoresis. Arthrobacter sp. synthesized and exhibited SOD activity in both aerobic and anaerobic conditions, thus suggesting other or additional physiological functions for this enzyme
La predazione negli allevamenti ovi-caprini dell’entroterra savonese
Get PDFPredation on domestic
stock has always been one of the main causes of the conflict between humans and large predators.
This problem has been recently spreading to new geographic areas, thus reinforcing the strength of this
conflict. In order to point out the characteristics and risk factors of predation in the Province of Savona
(Italy), we carried out a survey with direct inspections and interviews in 43 sheep and goats farms, 4 of
which make use of alpine pastures during the summer. Predation episodes seldom or never occur in
farms at the bottom of the valleys, whereas they commonly occur in 3 out of 4 farms during alpine summer
grazing periods. It has not always been possible to state with certainty the responsibility of the attacks. All
the events recorded in summer ranges were attributed to wolves and occurred during the night, while in
the farms at the bottom of the valley most of the attacks were due to stray dogs and predation occurred
mainly during daytime. Surplus killing was recorded in many cases. Principal risk factors were, first of
all, grazing in summer ranges, followed by the presence of large flocks and by a too high ratio animals/
stockmen. The presence of wolves is considered a problem by all grazing farmers, and only by 23% of
farmers at the bottom of the valley. Solutions proposed by the farmers to reduce the risk of predation by
wolves consist of wolf killing or, in second place, of setting up adequate reimbursement strategies. Very
few farmers are willing to accept financial support for the adoption of preventive measures. Among the
preventive strategies already adopted, electric fences seem to be the more effective, while guardian dogs
have not yield acceptable results so far
Evaluation of the Performance of a Warm Mix Asphalt (WMA) Considering Aged and Unaged Specimens
Get PDFIn the last decades, all technology production sectors reached a high level of development, without neglecting the attention to environmental aspects and safeguarding energy resources. Moreover, in the sector of pavement industry, some alternatives of bituminous mixtures were proposed to reduce the greenhouse gas emissions. One of these is the warm mix asphalt (WMA), a mixture produced and compacted at lower temperatures compared to traditional hot mix asphalt (HMA) (about 40 °C less), to allow a reduction of emissions into the atmosphere and the costs. Other operative benefits concern the health of workers during the whole road construction process, the reduction of distances to which the mixture can be transported, and therefore also the positioning of the plants. However, it is not all benefits, since reduced production temperatures can bring short- and long-term water sensitivity issues, which could threaten the pavement performance. This paper evaluated the performance (water sensitivity, stiffness, fatigue, and permanent deformation) of a WMA produced using a warm mix fabrication bitumen and compared it with an HMA tested in parallel. In general, except for the resistance to permanent deformation, the WMA presented performances comparable to HMA. Regarding the fatigue behavior of asphalt mixtures, the WMA was less affected by ageing conditions, despite it showing lower performance than HMA
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Fluorescent probes as markers of oxidative stress in keratinocyte cell lines following UVB exposure
No full textIn this work we describe the development of specific markers for determination of both the membrane and intracellular damage induced by free radicals generated by UVB radiation (5-150 mJ/cm(2)) in cultured keratinocytes. This using simple, specific and sensitive fluorescent probes: cis-parinaric acid (PNA) to monitor membrane lipid peroxidation and 2', 7'-dichloro-dihydrofluorescein diacetate (DCFH-DA) to evaluate the intracellular redox status, in parallel to the fluorimetric determination of the main intracellular antioxidant glutathione. To validate the methodologies, the changes in the intracellular oxidative status following exposure to low doses UVB were measured in both control and N-acetylcysteine-protected cells, in parallel with morphological analyses. UVB induces an early reduction of GSH inside the cell correlated with an increase in the intracellular peroxide content. The effects were time- and dose-dependent. In addition, using a sensitive fluorescent method, we quantitated the release of proteases, a family of proteolytic enzymes greatly involved in the onset/perpetuation of the free radical-induced skin damage from keratinocytes exposed to suberythemal UVB doses (5-15 mJ/cm(2)). The use of these fluorescent probes provides a reliable tool to detect the early signs of damage in keratinocyte cultures (when the apoptotic phenomenon has not yet been triggered) useful for future screening of protective molecules. (C) 2000 Elsevier Science S.A. All rights reserved
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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