1,721,681 research outputs found
Culicoides Latreille and Leptoconops Skuse biting midges of the southwestern United States with emphasis on the Canyonlands of southeastern Utah (Diptera: Ceratopogonidae)
No full textPhillips, Robert A. (2022): Culicoides Latreille and Leptoconops Skuse biting midges of the southwestern United States with emphasis on the Canyonlands of southeastern Utah (Diptera: Ceratopogonidae). Insecta Mundi 2022 (907): 1-214, DOI: 10.5281/zenodo.639168
Modified immunoglobulin-binding domains of Protein L from Peptostreptococcus magnus
No full textProtein L binds to the VL domain of κ-chains enabling it to bind to all sub-classes of antibodies that contain κ-chains. The complex formed between a single domain of wild-type Protein L and κ-chain is described by a dissociation constant (Kd) of approximately 150nM. Such domains, used as affinity ligands for the purification of κ-chains, or Igs bearing κ-chains, require harsh elution conditions to dissociate the complexes. This leads to degradation of the affinity column and the Ig or Ig fragment being isolated. The aim of the work described in this thesis was to develop variants of a single domain of Protein L that can offer more favoured binding characteristics improving their usefulness in some commercial applications. Thus mutants have been developed that have lower affinities for κ-chain (and Ig bearing κ-chain) but retain satisfactory conformational stabilities. A number of mutated domains have been purified and their binding properties to κ-chain characterised by ELISA, competitive ELISA, affinity chromatography and equilibrium and pre-equilibrium fluorescence spectroscopy. These studies have shown that whereas the F39W, the N26,76D, the N26,76D,F39W, and the K33W mutants all have low dissociation constants for their complexes with κ-chain of Ig, two mutants Y53H,F39W and F39H,Y64W have substantially higher Kd values. Both of these proteins were immobilised onto Sepharose 4B gel and used in affinity chromatography experiments. These showed that human Ig was released from these two proteins at pH 3.9 and 3.8 respectively and thus make useful affinity ligands. Pre-equilibrium binding studies have also provided a further insight into the possible mechanism by which κ-chains bind Protein L giving rise to the possibility that there are in fact two binding sites for κ-chain on a single domain of Protein L.</p
Interdormitory Council, Billy MacLennan, Floyd Ball, Yvonne Phillips, Robert White, Steve Wilson, Lige Brown
Full text linkStudents pictured who were named to the 1967 Interdormitory Council: (from left) Billy MacLennan, Floyd Ball, Yvonne Phillips, Robert White, Steve Wilson, and Lige Brownhttps://scholarsjunction.msstate.edu/ua-photo-collection/3880/thumbnail.jp
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
A new synonym of the biting midge, Culicoides bottimeri Wirth, with a redescription, new distribution records and seasonal activity data (Diptera: Ceratopogonidae)
No full textPhillips, Robert A., Grogan, William L., Jr, Mullens, Bradley A. (2006): A new synonym of the biting midge, Culicoides bottimeri Wirth, with a redescription, new distribution records and seasonal activity data (Diptera: Ceratopogonidae). Zootaxa 1122: 47-55, DOI: 10.5281/zenodo.17175
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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