100 research outputs found
Antonius Glock
No full textMedium: engravingprints"Antonius Glock" [1995.2385.000.000], Kilian, Philipp, Grambs, Johann ValentinArtist and Role: Kilian, Philipp, EngraverExtent: sheet 40.5 x 29.
Exercitatio Politica De Maiestatis Civilis Autoritate Et Officio Circa Leges / Quam ... Sub Praesidio ... Hermanni Conringii Philosoph. Et Med. Doctoris ... Ad diem Aprilis publico subiicit examini Esaias Philippus Glock Moeno-Francofurtensis
No full textPromenade militaire oder Wie die Herren Franzosen am 8. August 1914 in Mülhausen im Elsass einmarschierten und am 9. August wieder ausgezogen sind : ein tragi-kom. Heldengedicht in d. Tonart d. alten 'Ulrich Schartenmeyer' von anno 1870/71 / von Johann Philipp Glock
No full textAppartient à l’ensemble documentaire : BNUStras1Appartient à l’ensemble documentaire : BNUStr017Appartient à l’ensemble documentaire : BNUStr000Poési
Controlling and reshaping biological reaction-diffusion
No full textPattern formation by reaction-diffusion mechanisms is of crucial importance for the development and sustenance of all living beings. However, biological model systems so far lack the tools and versatility of the established chemical models. In this thesis, we set out to develop and expand the Min system of Escherichia coli towards becoming a universal model for biological reaction-diffusion in an in vitro setting. To this end, we firstly developed a strategy to control the Min reaction in situ. This was facilitated by incorporating a chemically synthesized azobenzene-moiety into a peptide derived from MinE. This MinE-peptide is capable of stimulating hydrolysis of ATP by MinD. Photoswitching the azobenzene crosslinker allows to also switch alpha-helicity of the peptide and therefore its activity. By periodically activating this peptide photoswitch we found resonance phenomena in the Min reaction. The photoswitch described here could thus be used in many synthetic biology scenarios, but also to learn about Min and biological reaction-diffusion systems. Secondly, we discovered that the Min system can form stationary patterns, which greatly expands the pattern diversity and therefore the phenomena which the Min model can help us understand. Especially when it comes to important decisions in development, such as cell fate or macroscopically visible effects such as fur patterns, stationary patterns are much more prominent than oscillations and waves. The discovery of these patterns also creates many opportunities for applications, especially when combined with the newly found ability of Min proteins to position arbitrary membrane-bound factors. Thirdly, this thesis shows that the Min system's complexity can be reduced even more by substituting MinE with small peptides. A combined theory-experiment approach outlines how pattern forming capabilities are restored in a small MinE-derived peptide either by adding membrane binding or by dimerizing it. This study further highlights how peptides and proteins excel as model morphogens due to their modularity and mutability. Lastly, protocols and resources are more easily available due to a combined method-paper and video that was published in open access.
In conclusion, by adding tools and versatility, this thesis introduces great progress towards establishing the in vitro Min system as the ideal model for biological reaction-diffusion
Design and Evaluation of an SVM Framework for Scientific Data Applications
No full textSupport vector machines (SVMs) are a popular classification method due totheir good accuracy and broad usage domains in scientific applications. Thecomputational complexity is between O(n2) and O(n3) for the number of n trainingsamples. The scalability for larger data sets is therefore a problem of SVMs. Withthe increasing number of large data problems, this disadvantage becomes moreand more significant. In order to overcome these scalability issues, this thesisdesigns and implements a parallel and scalable framework that realizes the cascadeSVM approach including specific improvements. A fundamental speed up andincreased scalability is gained by splitting up the data set into several sub setsthat can be worked on in parallel. The framework is designed to run in modernHigh Performance Computing (HPC) environments, that provide the necessarymassively parallel resources (e.g. large clusters with good node interconnects) tosolve large data problems. The framework however also works on a simple computerfor smaller problems if needed. To keep the interface usable for non-technical savvydomain scientists, Python is used.The standard cascade SVM approach is improved with a standardized file formatand parallel I/O is introduced that both improve the I/O performance, whichbesides computing is also often observed to be a bottleneck for large problems. Inorder to enable enhanced training speed up as well as a better accuracy furtherimprovements such as distance filters and cross-feedback options are realized andevaluated. The resulting improved cascade SVM approach and parallel and scalableframework design is then evaluated on a real world remote sensing data set andcompared to another parallel implementation called pi-SVM. The parallelizationstrategies of these two implementations are different whereby the cascade SVM is adata processing approach, pi-SVM follows primarily an algorithmic-driven approach
Requirements of industrial action in South Africa and Germany: a comparison
No full textMagister Legum - LLMThis paper investigated how the law of industrial action is shaped in South Africa and in Germany, which specific problems occur in South Africa and Germany, and how the different legal systems solve these problems. It also compared the different legal approaches of these two countries.South Afric
Die Haftung des Wirtschaftsprüfers für fehlerhafte Unternehmensbewertungen (Philipp Glock)
No full textEs war einmal : ein Kameruner Imortellenkranz deutscher Koloniallieder ; den Toten zum Gedächtnis, den Lebenden zur Erinnerung, den kommenden Geschlechtern zum Vorbild
No full textAntonius Glock Jctus. et Reipubl. Patriæ Mœnofrancofurtensis Syndicus Primarius : nat. An. M.DC.XI 2. 9br., denatus An. M.DC.LXXXX 29. 7br., ætat. LXXVIIII, Synd. XXXVI
No full textJ.V. Grams Pinx. ; Philipp Kilian Sculp
Lieder und sprüche aus dem Elsenztale; aus dem munde des volks gesammelt.
No full textZur deutschen volkskunde, no. 7.Reprinted from Alemannia, XXV.Photocopy.Mode of access: Internet
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