1,385 research outputs found
Celebration of Success in the Elimination of Iodine Deficiency Disorders in the Great Hall of the People Beijing 27 October 2000
No full textA speech given by Basil Hetzel in China.
Folklore and Literary Tradition in the Riddles of Basil Levshin
No full textAt the article the prosaic riddles of Basil Levshin, the writer of the second half of the XVIII century, are considered in the context of Russian folklore and literary traditions. Riddles are classified according to their thematic focus, a way to create interpretive field, the subject-object organization. In the process of comparative analysis, the author comes to the conclusion that most of the riddles of the writer characterized by cognitive and heuristic orientation. They reflected both cognitive picture of the world in the representation of contemporary society, and the specifics of the national concept sphere, as well as the submission of the author of the mythological model of the world
The role of C-C chemokine receptor 1 in skeletal muscle regeneration
No full textDiaphragmatic myotubes are known to constitutively express CCR1, a chemokine receptor in the C-C chemokine family, when cultured in vitro. It has been shown that CCR1 and its ligand CCL3 (MIP-1α) are directly involved in muscle repair responses in vitro. Furthermore, in vivo experiments, carried out in the MDX mouse model of muscular dystrophy, showed that these molecules were up-regulated in the dystrophic diaphragm muscle thus suggesting a role for CCR1 in inflammation and muscle healing. In this study, indeed, the role of CCR1 was investigated, with focus on inflammatory cell infiltration within the injured muscle using the freeze injury murine model. This study suggested that there is no significant difference in muscle regeneration or infiltration between CCR1-/- mice and their wild-type controls. There was also no difference in the muscle force between the knockout and their controls at 3, 7, and 14 days post injury. Investigation of individual infiltrating cell (macrophage, CD4 T-cells, CD8 T-cells) populations in the injured tissue yielded no significant difference. These data suggest that, although CCR1 has been found to play a role in myoblast proliferation and migration in vitro, it does not seem to have any apparent effect on muscle regeneration in vivo in the context of the freeze-injury model.In vitro, les myotubes diaphragmatiques expriment de façon constitutive CCR1, le récepteur de la famille des chemokines C-C. Il a été démontré que CCR1 et son ligand, CCL3 (MIP-1α), sont directement impliqués dans le processus de la réparation musculaire in vitro. De plus, des études in vivo dans la souris MDX ont démontré que l'expression de ces molécules augmente dans le diaphragme dystrophique. Ceci suggère un rôle pour CCR1 dans l'inflammation et la réparation musculaire. Dans cette étude, le rôle de CCR1 a été étudié avec un focus sur l'infiltration des cellules dans le muscle blessé suite à une blessure par congélation dans le modèle animal. Cette étude suggère qu'il n'y a aucune différence dans la réparation musculaire et l'infiltration cellulaire entre la souris CCR1 -/- et le contrôle. De plus, il n'y a aucune différence significative dans la force musculaire entre ces deux modèles à 3,7 et 14 jours suite à la blessure. L'étude individuelle des populations cellulaires (macrophages, cellules T CD4+ et CD8+) n'a montré aucune différence significative. Nos résultats suggèrent que malgré le rôle de CCR1 dans la prolifération et la migration de myoblastes in vitro, CCR1 n'est pas implique dans cette régénération post-traumatique in vivo
I Remember piece on the author\u27s failure to grow anything but basil on his Mai
No full textI Remember piece on the author\u27s failure to grow anything but basil on his Maine island
Architecture in tension: an examination of the position of the architect in the private and public sectors, focusing on the training and careers of Sir Basil Spence (1907-1976) and Sir Donald Gibson (1908-1991)
No full textIn the early 1900s tensions began to appear within the architectural profession,
as private practitioners struggled to deal with the implications of professional
colleagues moving into public sector employment. Sir Basil Spence and Sir
Donald Gibson began their architectural training in the mid-1920s and, as
tensions between the sectors intensified, Spence entered private practice and
Gibson chose to enter the public sector. Each became an exemplar of his
chosen sector of the profession and yet both have, until recently, escaped
critical attention. The tensions between the public and private sectors of the
profession have been acknowledged within the historiography, but not received
detailed analysis.
This thesis advances the current historiography by presenting an examination
of the division between the sectors, focusing on the relationship between the
RIBA and the public sector union AASTA and assessing the influence of
AASTA on Gibson's Coventry City Architect's Department.
Through an examination of archival material, contemporary published material,
and buildings, this thesis builds on the work of the Sir Basil Spence Archive
Project, adding detailed accounts of his early life, architectural training, and
RIBA presidency, presenting new information and correcting certain aspects of
the accepted historiography. It likewise presents new information on Gibson's
early life and training and his central role in achieving improved status and
representation for the public sector. An analysis of selected projects provides a
comparative study of their contrasting approaches to architecture: the
technically informed, collaborative team-work of Gibson and the individual
artistry of Spence.
Both men played pivotal roles in reforming the RIBA and in changing public and
professional perceptions of the architect, nevertheless, the long lineage and
complex nature of tensions within the profession meant that the public/private
division was never be bridged and issues of status and representation
remained essentially immutable
GOD AND BEINGIN BASIL OF CAESAREA
No full textThe article attempts to deepen our understanding of the problem of God’s essence in Saint Basil. Does Saint Basil identify God with being or does he exclusively wish to prove God’s total incomprehensibility? The author analyzes Saint Basil’s arguments concerning this matter and compares Basil’s statements with those defended by Eunomius with whom Basil polemicized. In defending his own position, Saint Basil defi ned several fundamental points of doctrine
Deep learning based protein stability prediction
No full textAuthor: Basil Ahmed Mohamed Abulellaangefertigt an der der Paris-Lodron-Universität Salzburg, Fachbereich Biowissenschaften und Medizinische BiologieMasterarbeit Johannes Kepler Universität Linz 2024Arbeit auf den öffentlichen PCs in den Bibliotheken der JKU+Medizin abrufba
Deep learning based protein stability prediction
No full textAuthor: Basil Ahmed Mohamed Abulellaangefertigt an der der Paris-Lodron-Universität Salzburg, Fachbereich Biowissenschaften und Medizinische BiologieMasterarbeit Johannes Kepler Universität Linz 2024Arbeit auf den öffentlichen PCs in den Bibliotheken der JKU+Medizin abrufba
Pilot Aquaponic Growing System of Carp (Cyprinus Carpio) and Basil (Ocimum Basilicum)
No full textAbstractThe aquaponic recirculating systems are integrated systems that combine fish and plant culture. These systems consist of two components: aquaculture and hydroponics components. In these systems the nutrients necessary for plant growth are resulted from the metabolism of food by the fish. This was obtained by recirculation of water, with a pump, from the fish tank to the hydroponic component and back to the fish tank. The experiment was conducted in the laboratory of Fisheries and Aquaculture of the Faculty of Animal Husbandry of University of Agronomic Sciences and Veterinary Medicine of Bucharest for 6 months. The system developed here, is a 1 m2 area of plant growth and 0.45 m3 of water in aquaculture component. In the hydroponic component river gravel was selected to support the plants and offer support for the growth and developing of nitrifying bacteria. The species cultivated were cultured carp (Cyprinus carpio) and basil (Ocimum basilicum). On average, there was obtained a quantity of about 1kg basil leaves in a period of 60 days of growth. It has been found that the species of plants grown in this system, namely basil (Ocimum basilicum) grown with carp (Cyprinus carpio), has a faster and better development compared to conventional growth. Use of basil as a purifying plant, resulted in the removal of nitrates, being not necessary to add additional water, as in classical recirculating systems, where is necessary to replace daily approx. 10% of the volume of the culture water being necessary to add into the system only water lost through evaporation. According to the results the basil is suitable for aquaponic system with carp culture. The basil was grown much better than the conventional cultivation
Supple Fig 1.tif
No full textBackground: Cystic fibrosis (CF) patients often suffer from skeletal
muscle atrophy, most often attributed to inactivity and nutritional factors. CF
is also characterized by abnormally elevated systemic inflammation. However, it
is unknown whether the lack of a functional CF transmembrane conductance
regulator (CFTR) gene predisposes to exaggerated inflammation-induced muscle
proteolysis.
Methods: CF mice (CFTR-/-) and their wild-type (WT=CFTR+/+) littermate controls
were systemically injected with Pseudomonas-derived
lipopolysaccharide (LPS). After 24 hours, the diaphragm and limb muscles (fast-twitch
tibialis anterior, slow-twitch soleus) were assessed
for induction of inflammatory cytokines (TNFa,
IL1b, IL6), oxidative stress, canonical muscle proteolysis
pathways (Calpain, Ubiquitin-Proteasome, Autophagy), muscle fiber histology, and diaphragm contractile function.
Results: At baseline, CF and WT muscles did not differ with
respect to indices of inflammation, proteolysis, or contractile function. After
LPS exposure, there was significantly greater induction of all proteolysis pathways
(Calpain activity; Ubiquitin-Proteasome: MuRF1 and Atrogin1; Autophagy: LC3B,
Gabarapl-1, BNIP3) in CF mice for the diaphragm and tibialis anterior, but not
the soleus. Proteolysis pathway upregulation and correlations with inflammatory
cytokine induction were most prominent in the tibialis anterior. Diaphragm
force normalized to muscle cross-sectional area was reduced by LPS to an
equivalent degree in CF and WT mice.
Conclusions: CF skeletal muscles containing
a high proportion of fast-twitch fibers (diaphragm, tibialis anterior) exhibit abnormal
upregulation of multiple muscle wasting pathways after exposure to an acute
inflammatory stimulus, but not under basal conditions. </p
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